Articles
<![CDATA[Oral Short-course Antibiotics Compliance Survey at Several Public Health Centres in Surabaya ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Widya Handayani]]>
<![CDATA[ Jurnal Farmasi Indonesia Vol 17 No 2 (2020): Jurnal Farmasi Indonesia ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Setia Budi ]]>
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DOI: 10.31001/jfi.v17i2.911
<![CDATA[Patients compliance is commonly occured in short-course antibiotics therapy. Patients compliance not only contributed to the therapeutics effect but also to prevent antibiotics resistance. Qualitatively, uncompliance in using antibiotics is affected by patients knowledge about antibiotics, improving symptomps, false in interpretating drug labels, activities, the lack of family suppor, and the lack of information given by healthcare provider. This study was aimed to observe patients compliance in using antibiotics assessed in how and howmany times they take their dosage, how they give interval between the doses, and whether they complete their course or not. The reasons behind their behaviour also investigated in this study. The survey was conducted at three public health centres in Surabaya. Patients who received short-course (3-5 days) antibiotics therapy were asked to participate in this study. The compliance was assessed using online developed self-assessment questionnaire containing 17 questions asking how they use their antibiotics and how many pills left sent in the last dosage day. The antibiotics prescription data was recorded as a refference in evaluating patients compliance. During research periods, a total of 100 patients were enrolled in this study. Of that, there were only 12.0% categoryzed as compliant. Most of patients did not give the same time interval between their doses (63,0%) and did not finished or prolonged their course (46,0%). The majority reasons behind their behaviour was feelings better or improving symptomps and simply forgot to take their antibiotics. A strengtnen in counselling and monitoring during their antibiotics course is needed in order to increase their compliance.]]>
<![CDATA[Potensi Interaksi Antar Obat dalam Peresepan Rawat Jalan Pasien Penyakit Jantung Akibat Hipertensi ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Yessy Asli Rahmawati]]>;
<![CDATA[Putri Febri Anggraini]]>
<![CDATA[ Jurnal Farmasi Indonesia Vol 19 No 1 (2022): Jurnal Farmasi Indonesia ]]>
Publisher : <![CDATA[Fakultas Farmasi Universitas Setia Budi ]]>
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DOI: 10.31001/jfi.v19i1.1253
<![CDATA[Hypertension or high blood pressure have contributed to the occurrence of cardiovascular disease. One of its complication is the development of Hypertensive Heart Disease (HHD). HHD pharmacological treatments usually combine antihypertensive and other agents that lead to polypharmacy. The use of multiple medications or polypharmacy will increase the potential of drug-drug interactions (PDDIs) that affect the therapeutic effect and increase adverse events. This study was aimed to analyze the prevalence and predictor of the PDDIs among HHD patients prescriptions in order to prevent the adverse effects and optimalize the therapy management. A retrospective observational study was conducted on HHD outpatients prescriptions. Medscape Drug Interaction Checker application was used to identify PDDIs. The mechanism, severity, number of interaction per prescription and most common interaction pairs of PDDIs were documented. In addition, age, gender, and the number of drug prescribed were analyzed as predictors of PDDIs using logistic regression binomial test. A total of 100 HHD outpatients prescriptions was analyzed and 94 of them had PDDIs. Majority of prescriptions had 3-4 and >4 PDDIs (33.00% each). Total of PDDIs observed were 397 cases. Most of PDDIs happened in the pharmacodynamic phase (86.40%) and need to monitored closely (93.20%). The concomitant use of Candesartan and Bisoprolol was found to be the most commpon interaction pair (11,08%) that can lead to the raise of potassium serum levels. The result of predictors analysis showed that the higher number of drug prescribed the higher the risk of the occurrence of PDDIs respectively (p-value 0,005) which addition 1 drug item will increase the PDDIs 7,232 time higher. In conclusion, the higher number of drug prescribed the closer monitoring need for PDDIs. In addition, closely monitoring in the elevating of potassium serum levels and the symptoms of hyperkalemia are needed in the treatment of HHD outpatients]]>
<![CDATA[Evaluasi Penggunaan Antibiotika Profilaksis Operasi Digestif Laparatomi ]]>
<![CDATA[Selly Septi Fandinata]]>;
<![CDATA[Eziah Ika Lubada]]>;
<![CDATA[Ilil Maidatuz Zulfa]]>
<![CDATA[ Journal Syifa Sciences and Clinical Research Vol 4, No 1 (2022): Volume 4 Edisi 1 2022 ]]>
Publisher : <![CDATA[State University of Gorontalo ]]>
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DOI: 10.37311/jsscr.v4i1.13496
<![CDATA[Laparotomy is a major operation and causes a lot of injuries, so the risk of infection of the laparotomy surgery wound is quite high. Surgical Site Infection (ILO) or Surgical Site Infection (ITP). Prevention of postoperative infection in patients with clean-contaminated surgery, and some clean operations with the use of prophylactic antibiotics. The purpose of this study was to evaluate the use of prophylactic antibiotics in patients with laparotomy surgery in a hospital in Surabaya. The research method is descriptive operational with retrospective data. The results of this study obtained as many as 160 patients aged 46-55 years at 20.6%, the sex of the respondents were dominated by male sex 66.3%, and the diagnosis of generalized peritonitis was 46.9%. The use of prophylactic antibiotics is class I cephalosporin antibiotics (cefazolin) with a dose of 1000-2000 mg, which is by the 2011 Ministry of Health guidelines.]]>
<![CDATA[The Qualitative Evaluation Of Antibiotics Used In Pediatric Respiratory Tract Infection Treatments At A Primary Hospital In Surabaya ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>
<![CDATA[ PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 15 No. 02 Desember 2018 ]]>
Publisher : <![CDATA[Pharmacy Faculty, Universitas Muhammadiyah Purwokerto ]]>
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DOI: 10.30595/pharmacy.v15i2.3636
<![CDATA[Respiratory Tract Infections (RTIs) commonly occur as an infection in children. A considerable amount of antibiotics consumption is used to treat RTIs in many hospitals. Unwise antibiotic treatments in RTIs will increase bacterial resistance and treatment cost. This study aimed to investigate the quality or appropriateness of antibiotics use in RTI treatments in pediatric inpatients. A retrospective analysis of antibiotics consumption data was conducted through inpatient medical records for three months in 2017 at a primary hospital in Surabaya, Indonesia. The qualitative assessment was performed using a modified Gyssens algorithm based on the National Guideline and other relevant international standards of antibiotics applications in RTI treatment. The medical records of a total of 87 pediatric inpatients aged 0-14 y.o. were included in this study. The most common diagnosis was tonsillopharyngitis (32.18%), and the average length of hospital stay was 4.84 days. Antibiotics used in the treatments were from the class of -lactams and cephalosporins, all of which were applied in empirical therapy. According to the analysis, the antibiotic treatments were not appropriate. The most inappropriate use of antibiotics was in the form of wrong choice of drug choice (95.40%), followed by the sub-optimal duration of antibiotics (4.60%). The RTI treatment in pediatrics has to avoid any inappropriate uses of antibiotics, which can be achieved through the evaluation of institutional policy against the local guideline, antibiogram, or any relevant international guidelines.]]>
<![CDATA[HUBUNGAN TINGKAT PENDIDIKAN DAN PENGETAHUAN PETUGAS APOTEK TERHADAP PELAYANAN ANTIBIOTIK ORAL DI KABUPATEN SIDOARJO, INDONESIA ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Fitria Dewi Yunitasari]]>
<![CDATA[ Majalah Farmasi dan Farmakologi Vol. 25 No. 2 (2021): MFF ]]>
Publisher : <![CDATA[Faculty of Pharmacy, Hasanuddin University ]]>
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DOI: 10.20956/mff.v25i2.13151
<![CDATA[Salah satu faktor yang berkontribusi pada resistensi bakteri adalah penggunaan antibiotik yang tidak rasional seperti pada fenomena penggunaan antibiotik tanpa resep. Fenomena penggunaan antibiotik tanpa resep yang terjadi tidak lepas dari pola pikir masyarakat maupun petugas apotek. Kurangnya pengetahuan petugas apotek tentang antibiotik, resistensi bakteri, dan aspek legal dari dispensing antibiotik berkontribusi pada pemberian layanan antibiotik di komunitas di beberapa negara dengan pendapatan rendah. Penelitian ini bertujuan untuk menganalisis hubungan tingkat pendidikan dan pengetahuan petugas apotek tentang antibiotik terhadap pelayanan antibiotik oral yang mereka berikan di Kabupaten Sidoarjo. Studi observasional dengan pendekatan secara cross sectional dilakukan kepada petugas apotek dengan membagikan kuisioner secara daring. Sebanyak 233 petugas apotek dari 56 apotek di Kabupaten Sidoarjo telah dilibatkan dalam penelitian. Sebagian besar dari responden memiliki pengetahuan baik tentang antibiotik (48,93%) serta hanya melayani antibiotik oral hanya berdasarkan atas resep (68,00%) walaupun masih sekitar 30,00% yang melayani berdasar resep dan non resep. Terdapat hubungan yang signifikan antara tingkat pengetahuan petugas apotek tentang antibiotik terhadap bentuk pelayanan antibiotik oral yang diberikan (p-value 0,001). Peningkatan pengetahuan petugas apotek tentang antibiotik akan berkontribusi pada bagaimana mereka melayani anitibiotik berdasarkan aturan yang berlaku sehingga peningkatan pengetahuan tentang antibiotik ditengah petugas apotek yang bertugas di layanan sangat penting untuk dilakukan.]]>
<![CDATA[PENINGKATAN KEPATUHAN PENGGUNAAN ANTIBIOTIK ORAL MELALUI KALENDERISASI KEMASAN OBAT ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Widya Handayani]]>
<![CDATA[ Majalah Farmasi dan Farmakologi Vol. 26 No. 1 (2022): MFF ]]>
Publisher : <![CDATA[Faculty of Pharmacy, Hasanuddin University ]]>
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DOI: 10.20956/mff.v26i1.14109
<![CDATA[Ketidakpatuhan dalam penggunaan antibiotik dapat meningkatkan resistensi bakteri. Faktor-faktor yang mempengaruhi kepatuhan pasien dalam menggunakan antibiotik adalah lupa, sibuk, dan kurangya pengetahuan. Beberapa penelitian pengembangan upaya peningkatan kepatuhan telah dilakukan seperti pemberian informasi, edukasi, dan konseling yang terbukti dapat meningkatkan kepatuhan penggunaan antibiotik. Namun, hal tersebut terkadang sulit dilakukan terlebih pada fasilitas kefarmasian dengan workload yang tinggi. Sebuah inovasi kalenderisasi kemasan obat telah diterapkan pada pasien hipertensi dan terbukti meningkatkan kepatuhan penggunaan obatnya. Penelitian ini bertujuan untuk menganalisis pengaruh kalenderisasi kemasan antibiotik pada kepatuhan pasien dalam menuntaskan terapi antibiotiknya. Studi dilakukan pada pasien usia 19-55 tahun yang menebus resep antibiotik oral tunggal jangka pendek (<7 hari), tidak mengkonsumsi lebih dari 5 obat per hari, dan bersedia bergabung dalam penelitian. Pasien dibagi kedalam dua kelompok yaitu kelompok kontrol dan kelompok dengan kalenderisasi pada kemasan antibiotiknya. Kepatuhan penggunaan antibiotik diukur dengan metode pill count pada hari seharusnya antibiotik habis. Jumlah pasien yang patuh akan dibandingkan dari kedua kelompok tersebut. Hasil menunjukkan sebanyak 23(92,00%) pasien patuh dalam menggunakan antibiotiknya dalam kelompok kalenderisasi sementara dalam kelompok kontrol hanya sebanyak 6 pasien (24,00%). Perbedaan jumlah tersebut menunjukkan hasil yang signifikan secara statistik sehingga dapat disimpulkan kalenderisasi kemasan obat dapat mempengaruhi kepatuhan penggunaan antibiotik jangka pendek. Namun, studi lebih lanjut dengan jumlah sampel lebih besar, randomisasi, dan perhitungan sisa obat secara langsung perlu dilakukan untuk mengkonfirmasi hasil penelitian ini.]]>
<![CDATA[EDUKASI GENERASI MUDA SIAP VAKSINASI COVID-19 ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Fitria Dewi Yunitasari]]>
<![CDATA[ Jurnal Abdi Masyarakat Kita Vol 1 No 2 (2021): Jurnal Abdi Masyarakat Kita ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/asta.v1i2.149
<![CDATA[Vaccination program for Covid-19 in Indonesia has been conducted since 13th of January 2021. However, the vaccination process has been accompanied by an increase false information that can lead to the decrease of public acceptance. Therefore, public education strengthening is a key concerns to succed the vaccination program. This was a report of public education strengthening activity conducted in April 2021 aimed to increase public awareness about Covid-19 vaccination program. There were 34 highschool students joined in the event. The result showed after joining the events 14,7% of students who refuse to support vaccinated program claim thet they are ready for vaccination. In conclusion, continuity in public education strengthening is essential to increase public acceptance about Covid-19 vaccination.]]>
<![CDATA[Keamanan Obat Untuk Ibu Hamil Dan Menyusui ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Widya Handayani]]>
<![CDATA[ Jurnal Abdi Masyarakat Kita Vol 2 No 1 (2022): Jurnal Abdi Masyarakat Kita ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/asta.v2i1.205
<![CDATA[Pregnancy and breastfeeding are special conditions that need to be considered when taking drugs because not all drugs are safe for pregnant and breastfeeding mother. Mistakes in drug consumption can harm the fetus and baby. In the community, pregnant women and breastfeeding mothers often have difficulty in choosing symptomatic drugs available at pharmacies and drug stores due to the lack of knowledge about the safety of drugs for these conditions. Related to this, it is very important to increase public knowledge through the provision of information and tips so that people no longer have difficulty in choosing safe medicines for these conditions.]]>
<![CDATA[Edukasi Masyarakat Mengenai Suplemen dan Vitamin untuk Tumbuh Kembang Remaja dan Covid-19 ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Fitria Dewi Yunitasari]]>
<![CDATA[ Jurnal Abdi Masyarakat Kita Vol 2 No 2 (2022): Jurnal Abdi Masyarakat Kita ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/asta.v2i2.284
<![CDATA[Covid-19 pandemic has hit worldwide for three years. During the pandemic, a proper diet and optimum consumption of vitamins and suplements will help to maintain the immune system. However, there is still lack of public awareness in fulfillness the nutrition need during pandemic. Hence, it is essentials to increase public knowledge and awareness through the through the provision of information in order to make people easier in choosing the best diet, vitamins and suplement to combat the pandemic.]]>
<![CDATA[A SURVEY OF PHARMACY STAFF KNOWLEDGE RELATED TO ANTIBIOTICS IN SIDOARJO, INDONESIA ]]>
<![CDATA[Ilil Maidatuz Zulfa]]>;
<![CDATA[Fitria Dewi Yunitasari]]>
<![CDATA[ Jurnal Farmasi Sains dan Praktis Vol 6 No 2 (2020) ]]>
Publisher : <![CDATA[Universitas Muhammadiyah Magelang ]]>
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DOI: 10.31603/pharmacy.v6i2.3795
<![CDATA[Antibiotics resistance still remains the problem in treating infection disease both in developing and developed country. One of the factor contribute to the increase of antibiotics resistance is irrational antibiotics use without prescriptions. There is still lack of information about factors related to the antibiotics dispense by pharmacy staff. This study was aimed to observe pharmacy staff knowledge about the pharmacology and the regulation of antibiotics. A cross sectional online survey using questionnaire was conducted to pharmacy staff who work for service in Sidoarjo from February to April 2020. The knowledge of antibiotics was classified into lack, enough, and good knowledge. A total of 233 respondents from 56 pharmacy recruited in this study. Of them, 17,17% were pharmacist; 10,73% were pharmacy technician; 52,36% were pharmacy assistant and 19,74% non pharmacy worker. Overall the majority of respondents had a good knowledge about antibiotics (48,93%). However, most of them did not know that only pharmacist who had responsible to dispense antibiotics based on prescriptions (58,37%), fail to describe antibiotics indications (46,35%) and had poor knowledge about the minimum length of antibiotics course (58,37%). Educating and upskilling pharmacy personel about antibiotics will minimize the irrational use of antibiotics which lead to the increase of antibiotics resistance caused by the lack information received by patients.]]>
