Sunaka, I Wayan
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Chronic Pulmonary Aspergillosis with Tracheobronchial Involvement Hermawan, Yosua Kevin; Pranata, Anak Agung Ngurah Satya; Putra, Wayan Wahyu Semara; Sunaka, I Wayan; Novitasari, Novitasari; Angelina, Cokorda Rio
Jurnal Respirasi Vol. 10 No. 3 (2024): September 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.3.2024.249-256

Abstract

Introduction: Aspergillosis is a fungal infection commonly found in human lungs and takes several forms. Chronic pulmonary aspergillosis (CPA) commonly affects individuals with underlying disease, most usually lung tuberculosis (TB). Aspergillosis can cause the formation of a fungus ball in the lung cavity and can also manifest in the tracheobronchial area, although this is rarely seen in immunocompetent patients. Case: A 23-year-old woman came with persistent cough, hemoptysis, and shortness of breath for 4 months. The patient also had a significant weight loss and a history of lung TB 3 years ago. She had completed her lung TB medication. Physical examination showed increased respiratory rate and rhonchi on the left lung. GeneXpert showed no Mycobacterium tuberculosis (MTB) detected. The chest X-ray showed a cavity on the left superior lobe of the lung. Bronchoscopy showed multiple plaques along the trachea, carina, and left main bronchus. A chest computed tomography (CT) scan with contrast enhancement was performed, and a fungus ball was found inside the cavity in the left upper lobe of the lung. The patient was given intravenous fluconazole as therapy and continued with oral fluconazole when discharged. A second bronchoscopy was performed, and improvement was shown. Conclusion: Early detection and treatment should be applied to CPA patients since some studies showed poor prognosis and low five-year survival rates.
Neoplasia Limfoid yang Menyerupai Mesotelioma: Laporan Kasus Irianto; Puteri, Made Widya Wirayanti; Sunaka, I Wayan; Novitasari
Cermin Dunia Kedokteran Vol 52 No 6 (2025): Kesehatan Jiwa
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i6.1366

Abstract

Introduction: Lymphoid neoplasms are abnormalities of the hematopoiesis process of the lymphoid line, which can lead to lymphoma or leukemia. Mesothelioma is an abnormal mesothelial cell growth strongly associated with asbestos exposure. In radiology, mesothelioma is usually described as a tissue-dense lesion with well-defined, spiculated borders attached to the thoracic wall. The picture actually only depicts a tissue attached to the thorax, which can be suspected as mesothelioma, but can also be due to other disease processes, such as leukemia, lymphoma, and tuberculosis. Case: A 58-year-old man presented to the emergency room with complaints of shortness of breath. The patient was initially suspected of mesothelioma with suspicion of blood malignancy, but it turned out that the biopsy results were more likely to lead to infiltration of lymphoid neoplasms. Conclusion: In this patient, a lymphatic neoplasm infiltrated the mesothelial tissue and produced a well-demarcated and spiculated tissue picture resembling mesothelioma. Biopsy examination as the gold standard cannot be replaced by radiologic imaging at this time, as many other disease processes can mimic a malignancy.