Yunus, Fanny Thresia
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The Effect Of Sensory-Motor Virtual Reality on Balance in Children with Clinical Down Syndrome Yunus, Fanny Thresia; Widagda, I Made; Isma, Rahmi
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.42137

Abstract

Introduction: Down syndrome affects approximately one in every 800 live births and leads to musculoskeletal disorders and motor skill delays. Children with down syndrome experience persistent deficits in balance and coordination. Virtual reality (VR) offers an interactive and immersive approach to therapy and has gained popularity in rehabilitation. This study explores the effect of sensory-motor virtual reality (VR SenMor) on static and dynamic balance in children with clinical down syndrome. Methods: A randomized controlled trial with a pre and post-test control group design was conducted with 20 children diagnosed with down syndrome. Treatment group (n = 10) received VR SenMor therapy twice a week for four weeks, while the control group (n = 10) received no treatment. Balance assessments were conducted using the pediatric balance scale (PBS) and timed up and go (TUG) test before and after the intervention. Results: There were no significant differences in age, gender, or BMI between the intervention and control groups. The VR SenMor therapy resulted in significant improvements in the PBS and TUG test scores in the intervention group compared to the control group. Discussion: VR SenMor therapy enhanced balance in children with down syndrome, with no confounding effects from age and gender. The VR system's sensory integration feedback and neuroplasticity mechanisms contributed to the improvements. The treatment's positive outcomes make it a promising approach for balance training at home. Conclusion: Sensory-motor virtual reality therapy shows promise in enhancing static and dynamic balance in children with clinical down syndrome.
IDENTIFIKASI SENYAWA GARLISIN DAN KUERSETIN SEBAGAI SENYAWA ANTIMIKROBA PADA SEDIAAN BASAH DAN KERING BAWANG PUTIH (Allium sativum L.) Yunus, Fanny Thresia; Suwondo, Ari; Martini, Martini
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 8, No 2 (2020): EDITION JULY 2020
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.09 KB) | DOI: 10.33366/jc.v8i2.1693

Abstract

Indonesian people have long used garlic as traditional medicine because it contains various chemical compounds that are beneficial to the body. In this study identification of garlicin and kuersetin compounds in garlic as an antibacterial. This study requires 500 grams of garlic each in wet preparations consist of fine garlic and garlic extract, and dry preparation consists of garlic powder. In addition, this research requires 2,1 liters of 96% ethanol. Garlic is dried at 400C with TMI Vacuum Oven and extracted at 250C. Garlic powder is made using Krisbow dry cabinet with a temperature of 1000F and a pressure of 10 Pa. Garlisin content was identified by GCMS Shimadzu TQ8030 and FTIR Perkin Elmer Spectrum Two UATR, while identification of quercetin using Shimadzu HPLC type UFLC. The result shows that the compound garlicin (C6H10S2) was found in the three samples with identical similarity levels. In addition, the three samples showed differences in kuersetin content. The highest kuersetin content was 458.729 ppm garlic extract while the lowest kuersetin content was 81.181 ppm fresh garlic. Both of these compounds have potential as antimicrobial compounds.