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All Journal Jurnal Respirasi (JR) Jurnal Abdi Masyarakat Indonesia Folia Medica Indonesiana
Syafa'ah, Irmi
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Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Health Professions Medicine & Pharmacology Neuroscience Public Health

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The Effect of Vitamin D3 Supplementation on Interleukin-6 and PRESS Score in Children with Pneumonia and Vitamin D Deficiency Setyoningrum, Retno Asih; Kristianto, Wigit; Chafid, Arda Pratama Putra; Hapsari, Rika; Syafa'ah, Irmi
Jurnal Respirasi Vol. 11 No. 2 (2025): May 2025
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v11-I.2.2025.107-113

Abstract

Introduction: Pneumonia is a significant health issue in children under 5 years old. Vitamin D may help to reduce childhood mortality, morbidity, and interleukin-6 (IL-6) levels in children with pneumonia, but the evidence is still limited and controversial. This study aimed to evaluate the effect of vitamin D3 supplementation on IL-6 levels and clinical manifestations in children with pneumonia and vitamin D inadequacy. Methods: This was a randomized, placebo-controlled, and double-blinded trial study. Twenty-eight children diagnosed with pneumonia and vitamin D deficiency were enrolled and divided into a supplementation (n=15) or placebo group (n=13). Children were given a single dose (100,000 international units/IU) of vitamin D3 or placebo on the first day of hospitalization. Clinical manifestations were assessed by the Pediatric Respiratory Severity Score (PRESS). Results: The level of 25-hydroxyvitamin D (25-OH D3), IL-6, and PRESS score at baseline showed no significant difference between groups. Seven days post-supplementation, only the PRESS score showed a significant difference between groups (p=0.025). Analysis of the vitamin D3 group showed a significantly increased 25-OH D3 level and a reduced PRESS score (p=0.039 and p=0.02, respectively). Conclusion: A single high dose of vitamin D3 supplementation in children with pneumonia and inadequate vitamin D levels helps elevate 25-OH D3 levels and reduce clinical manifestations, as indicated by the PRESS score.
The Improvement of Community Knowledge, Attitudes and Practices After Covid-19 Socialization Khaerunnisa, Siti; Syafa'ah, Irmi; Wungu, Citrawati Dyah Kencono; Prabowo, Gwenny Ichsan; Handajani, Retno; Safitri, Indri; Notopuro, Harianto; Qurnianingsih, Ema; Lukitasari, Lina; Humairah, Ira; Bakhtiar, Arief; Suwandito, Suwandito; Asih, Susi Wahyuning; Anggraeni, Zuhrotul Eka Yulis; Adi, Ginanjar Sasmito; Nugrahani, Ely Rahmatika; Zulka, Ayesie Natasha; Soetjipto, Soetjipto
Folia Medica Indonesiana Vol. 57, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low attitude, very high practice, high practice, sufficient practice, and low practice were 58.33 ± 30.97, 77.70 ± 22.52, 62.5±21.7, 31±22.2, 6.5±17.1, 65±13.8, 32.3±13.8, 1.25±2.4, 1.25±1.8, respectively. Knowledge pre-test and post-test correlated 0.819 (p=0.001) and a t-test with p=0.003. Attitudes and practices correlated with p=0.001. Socialization of COVID-19 was useful to improve the community knowledge, attitudes, and practices in Rambipuji and Suci Village, Jember District, East Java, Indonesia that could prevent the transmission and inhibit the spread of the COVID-19 pandemic in Indonesia. Furthermore, continuous encouragement of COVID-19 socialization in wide areas was recommended.
Case Report: Survival of A Coronavirus Disease-2019 (Covid-19) Patient with Acute Respiratory Distress Syndrome (ARDS) in Dr. Soetomo Hospital, Surabaya, Indonesia Soedarsono, Soedarsono; Semedi, Bambang Pudjo; Setiawati, Rosy; Meliana, Resti Yudhawati; Kusmiati, Tutik; Permatasari, Ariani; Bakhtiar, Arief; Syafa'ah, Irmi; Indrawanto, Dwi Wahyu
Folia Medica Indonesiana Vol. 56, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China has spread rapidly in multiple countries of the world and has become a pandemic. Currently, there is no vaccine or specific antiviral for COVID-19. A study reported 7.3% of critical patients admitted to ICU, 71% of them required mechanical ventilation, and 38.5% of them were survived. Herein, we reported a 54 year old man with Acute Respiratory Distress Syndrome (ARDS) of COVID-19 who survived the disease. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay of nasopharyngeal and oropharingeal swabs were positive for SARS-CoV-2. Diagnosis of ARDS was also according to clinical symptoms, laboratory, chest radiograph, and chest CT scan. Alcaligenes faecalis and Candida albicans were also identified from sputum culture. Treatment for this patient was causal and supportive therapy, including antibiotic, antiviral, and antifungal therapy according to the culture results, fluid resuscitation, and oxygen supply from the mechanical ventilator. This patient was survived and discharged on hospital day-29. A fibrosis in parenchyma pulmonary and sensory peripheral neuropathy occurred after survived from ARDS. Monitoring of clinical, laboratory, and chest radiograph were continued after the patient discharged from the hospital. This case highlights the importance of early diagnosis and effective treatment to the care of COVID-19 patient.
Pengabdian Masyarakat melalui Penyuluhan dan Pemberian Modul Tuberkulosis (TB) Paru sebagai Upaya Peningkatan Pengetahuan dan Kinerja Kader TB di Pondok Pesantren Annuqoyah, Kabupaten Sumenep, Jawa Timur Bakhtiar, Arief; Kusmiati, Tutik; Syafa'ah, Irmi; Tanoto, Julius; Aulia Rahman, Nuha; Rahmawati Hariputri, Wulan; Najich Riza Firmansyah, Achmad; Maulaningtyas, Hamidia; Firdausi Rafidah, Salsabila
Jurnal Abdi Masyarakat Indonesia Vol 6 No 1 (2026): JAMSI - Januari 2026
Publisher : CV Firmos

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54082/jamsi.2464

Abstract

Eliminasi tuberkulosis (TB) masih menjadi tantangan kesehatan masyarakat di Indonesia, termasuk di Kabupaten Sumenep, yang pada tahun 2021 belum mencapai target penemuan dan pengobatan kasus TB. Tingginya jumlah pondok pesantren di wilayah ini menjadikan pesantren sebagai sasaran strategis dalam upaya eliminasi TB. Pondok pesantren dengan kepadatan hunian dan intensitas kontak antar santri yang tinggi berpotensi meningkatkan risiko penularan. Kegiatan pengabdian masyarakat ini bertujuan meningkatkan pengetahuan dan peran kader TB pesantren yang telah ditunjuk dalam mendukung upaya eliminasi TB. Kegiatan dilaksanakan di Pondok Pesantren Annuqayah, Kecamatan Guluk-Guluk, Kabupaten Sumenep, yang sebelumnya belum memiliki kader TB pesantren. Pengabdian masyarakat dilakukan melalui penyuluhan dengan metode ceramah, diskusi, dan simulasi, disertai pemberian modul TB paru dan lembar balik sebagai media edukasi. Evaluasi dilakukan menggunakan pretest dan posttest, kemudian dianalisis dengan uji t berpasangan. Hasil menunjukkan peningkatan pengetahuan kader yang signifikan, dengan nilai rata-rata pretest sebesar 36,87 meningkat menjadi 71,96 pada posttest (p=0,000). Selain itu, kader menunjukkan peningkatan peran aktif melalui penemuan santri terduga TB dalam tiga bulan setelah kegiatan. Kegiatan ini efektif dalam meningkatkan kapasitas kader TB pesantren dan diharapkan dapat memperkuat peran kader dalam mendukung eliminasi TB di lingkungan pesantren.
Co-Authors Adi, Ginanjar Sasmito Anggraeni, Zuhrotul Eka Yulis Aulia Rahman, Nuha Bakhtiar, Arief Chafid, Arda Pratama Putra Ely Rahmatika Nugrahani, Ely Rahmatika Firdausi Rafidah, Salsabila Harianto Notopuro Humairah, Ira Indrawanto, Dwi Wahyu Indri Safitri, Indri Khaerunnisa, Siti Kristianto, Wigit Kusmiati, Tutik Lukitasari, Lina Maulaningtyas, Hamidia Najich Riza Firmansyah, Achmad Permatasari, Ariani Prabowo, Gwenny Ichsan Qurnianingsih, Ema Rahmawati Hariputri, Wulan Resti Yudhawati Retno Asih Setyoningrum Retno Handajani Rika Hapsari Semedi, Bambang Pudjo Setiawati, Rosy Soedarsono Soedarsono SOETJIPTO . Susi Wahyuning Asih, Susi Wahyuning Suwandito, Suwandito Tanoto, Julius Wungu, Citrawati Dyah Kencono Zulka, Ayesie Natasha