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All Journal Jurnal Ilmu Kedokteran dan Kesehatan
Choerunnisa, Nida
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Challenges In Managing HIV-Associated Co-Infection With Tuberculosis And Suspected Pneumocystis jirovecii pneumonia (PCP): A Case Report. Sinaga, Fransisca T Y; Saputra, Tetra Arya; Choerunnisa, Nida
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 7 (2025): Volume 12 Nomor 7
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i7.21866

Abstract

HIV-positive individuals are highly vulnerable to opportunistic infections such as tuberculosis (TB) and Pneumocystis jirovecii pneumonia (PCP), particularly in low-resource, TB-endemic regions. We report a 30-year-old male patient with a history of unprotected multipartner sexual activity, diagnosed with clinical pulmonary TB and HIV infection, who developed progressive dyspnea, hypoxemia, and systemic symptoms over a four-month period. Physical examination revealed signs of pulmonary consolidation and neurologic abnormalities. Laboratory tests showed leukocytosis, hypoalbuminemia, and electrolyte imbalances. Imaging demonstrated bilateral lung infiltrates. The patient received antimicrobial therapy, electrolyte correction, and supportive care. Co-infection of TB and HIV with suspected PCP complicates diagnosis and necessitates an integrated approach. Clinicians must maintain high suspicion for overlapping infections in HIV-positive patients with deteriorating respiratory symptoms. Prompt clinical assessment, empiric therapy, and multidisciplinary management are essential in improving outcomes in resource-limited settings.
Keberhasilan Pleurodesis Bleomisin Pada Pneumotoraks Spontan Sekunder Berulang Akibat Tuberkulosis Paru: Laporan Kasus Mustofa, Syazili; Fitri, Reggina Annisa; Choerunnisa, Nida; Soemarwoto, Retno Ariza; Putri, Giska Tri; Busman, Hendri
Jurnal Ilmu Kedokteran dan Kesehatan Vol 13, No 3 (2026): Volume 13 Nomor 3
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v13i3.23187

Abstract

Pneumotoraks spontan sekunder merupakan komplikasi serius tuberkulosis paru dengan risiko kekambuhan yang tinggi. Dilaporkan seorang perempuan 17 tahun dengan tuberkulosis paru yang mengalami pneumotoraks berulang meskipun telah dilakukan pemasangan chest tube. Pasien kemudian menjalani pleurodesis menggunakan bleomisin, dengan hasil resolusi klinis dan radiologis lengkap tanpa kekambuhan selama 2 bulan follow-up. Temuan ini menunjukkan bahwa pleurodesis bleomisin berpotensi menjadi pilihan terapi yang efektif pada pneumotoraks spontan sekunder berulang terkait tuberkulosis, terutama pada kasus yang tidak responsif terhadap chest tube. Secara klinis, pendekatan ini dapat dipertimbangkan sebagai alternatif minimal invasif pada pasien dengan kontraindikasi tindakan bedah atau risiko kekambuhan yang tinggi.
Co-Authors Fitri, Reggina Annisa Giska Tri Putri Hendri Busman Saputra, Tetra Arya Sinaga, Fransisca T Y Soemarwoto, Retno Ariza Syazili Mustofa