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Humaidi, Fauzan
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Biochemistry, Genetics & Molecular Biology Chemistry Medicine & Pharmacology

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Patterns of Use of Antihypertensive Drugs in Hypertensive Patients in the Outpatient Unit of the Kowel Health Center, Pamekasan Regency Alrosyidi, Ach Faruk; Humaidi, Fauzan; Ayu Lokahita, Dyah
Berkala Ilmiah Kimia Farmasi Vol. 9 No. 1 (2022): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v9i1.40898

Abstract

Inappropriate use of drugs had a large and detrimental impact on the unit or healthcare institution for patients and the community. Therefore, it was necessary to select and use drugs appropriately, so that drug interventions could achieve their goals (patient healing) with minimal drug side effects. This study aimed to determine the pattern of use of antihypertensive drugs in patients with hypertension in the outpatient unit of Kowel Health Center, Pamekasan Regency. Samples were taken from medical records of hypertensive patients from January to May 2022, with a total sample of 75 patients. The research variables included the type of drug, dose, frequency, duration of use, side effects, drug interactions, and patient control routines. The most widely used single dose drug was the calcium antagonist amlodipine, in 46 patients (61.33%). The highest combination dose was found in calcium antagonist + ACE inhibitor, namely amlodipine and captopril, in 3 patients (4%).Keywords: Antihypertensive Drugs, Kowel Health Center, the Pattern of Use of Drugs
Analysis of Cyclamate Content in Unbranded Instant Herbal Medicinal Drink on Market in the City of Pamekasan Jamila, Nur; Rahman, Alief Putriana; Humaidi, Fauzan
Berkala Ilmiah Kimia Farmasi Vol. 10 No. 2 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v10i2.51955

Abstract

Jamu was one of the traditional medicines because most herbal medicine used natural ingredients or plants. One of the safety of herbal medicine was the absence of abuse such as the addition of artificial sweeteners in the form of cyclamate. Cyclamate was one of the artificial sweeteners that had a sweetness level 30 times higher than natural sweeteners. Excessive use of cyclamate could cause cancer and tumors. The purpose of this study was to determine the presence or absence of cyclamate content and levels in ready-to-drink herbal medicine without a brand sold in the Pamekasan City market. This research was conducted qualitatively with precipitation methods and quantitative with gravimetric methods. From qualitative research, the results of sample A found a white precipitate which indicated a positive sample containing cyclamate. While samples B and C found no deposits indicating that the sample was negative cyclamate. Furthermore, a positive sample was carried out quantitative testing. In determining cyclamate levels, sodium cyclamate levels in sample A were obtained at 4,8047 g/kg, so that the serving rate or per 1 bottle of herbal medicine contains 115,312 g/0,6 kg. This exceeded the threshold determined by BPOM Regulations which is 1,25 g/kg. The conclusion of this study was that 1 out of 3 positive samples contains cyclamate with levels that exceeded the threshold determined by BPOM RI No. 32 of 2019. Keywords:  Jamu, Cyclamat, Gravimetry
Detection of Aflatoxin Content in Candlenut (Aleurites moluccana) Simplicia at Karang Penang Market using PDA (Potato Dextrose Agar) Method Indriyani, Nova; Rahman, Alief Putriana; Humaidi, Fauzan
Berkala Ilmiah Kimia Farmasi Vol. 11 No. 1 (2024): June
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikfar.v11i1.51957

Abstract

Candlenut (Aleurites moluccana) was a food ingredient widely used as a cooking spice. Candlenuts that were stored for too long rotted more easily and grew fungi, especially Aspergillus niger and Aspergillus flavus. These types of fungi could produce mycotoxin compounds which were dangerous when consumed by humans. The purpose of this study was to determine the presence of aflatoxin content in candlenut (Aleurites moluccana) in the Karang Penang Sampang market. This research used total sampling. Candlenuts chosen as samples were all the candlenuts sold unwrapped by sellers in the Karang Penang market. This method used PDA media with the Pour Plate technique and an incubation time of 7 days. The results of the study showed 8 samples of candlenut with positive packaging containing the fungus Aspergillus niger with blackish-brown colonies and 1 sample of candlenut without positive packaging containing the fungus Aspergillus flavus with round yellowish-green colonies. In this study, it was concluded that the candlenuts circulating in the Karang Penang Sampang Market were positive for Aspergillus niger and Aspergillus flavus. Keywords:  Soft Capsule, Increase Effectiveness, α-tocopherol, Vitamin E, Antioxidant
Co-Authors Alief Putriana Rahman Alrosyidi, ach Faruk Ayu Lokahita, Dyah Indriyani, Nova jamila, Nur