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All Journal Jurnal Kimia Mulawarman PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Jurnal Aisyah : Jurnal Ilmu Kesehatan Jurnal Farmagazine Binawan Student Journal COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Indonesian Health Journal Journal Prima Health Science Journal of Natural Product for Degenerative Diseases
Zahara, Indah
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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FORMULASI SEDIAAN DEODORAN ROLL ON DENGAN MINYAK SIRIH (Piper betle Linn.) SEBAGAI ANTISEPTIK Indah Zahara
Jurnal Farmagazine Vol 5, No 1 (2018): Jurnal Farmagazine
Publisher : STF Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47653/farm.v5i1.89

Abstract

Minyak sirih (Piper betle Linn) dengan kandungan utama kavikol yang berfungsi sebagai antiseptik diformulasi menjadi sediaan deodoran roll on dengan basis etanol 96%. Sifat antiseptik ditentukan oleh zat-zat yang berfungsi sebagai antibakteri yang terkandung dalam minyak atsiri yang terdapat pada tumbuhan. Deodoran roll on dibuat dengan kandungan minyak sirih dengan konsentrasi 0; 0,5; 1,0; 1,5 %. Prinsip pembuatan deodoran roll on adalah dengan melarutkan komponen yang larut dalam air dan yang larut dalam etanol 96%. Evaluasi yang dilakukan pada sediaan deodoran roll on meliputi homogenitas, organoleptik, pH, viskositas, sifat alir, uji iritasi, dan daya hambat terhadap minyak sirih serta sediaannya, yang kemudian dibandingkan dengan deodoran roll on pembanding yang ada di pasaran. Hasil evaluasi daya hambat minyak sirih dan sediaannya serta pH dianalisis secara statistik dengan metode anva satu arah dan dua arah. Hasil penelitian menunjukkan bahwa semakin tinggi konsentrasi minyak sirih maka semakin besar pula kemampuan menghambat bakteri. Daya hambat paling besar pada kosentrasi 1,5% yaitu pada formula IV dengan karkteristik sebagai berikut: Homogenitas baik, berwarna putih susu, bau khas sirih, pH antara 3,97-3,98, viskositas berkisar antara 230-300 cPs, memiliki sifat alir tiksotropik, tidak mengiritasi kulit, dan diameter hambat bakteri Staphylococcus epidermidis 0,80-1,00 cm. Kata kunci :Minyak sirih, Antiseptik, Deodoran roll on
Hubungan Tingkat Pengetahuan Pasien Dengan Perilaku Swamedikasi Terhadap Penggunaan Obat Metampiron Secara Rasional Di Apotek Guardian Summarecon Mall Bekasi Kecamatan Bekasi Utara Indah Zahara; Prita Ardianti; Widayanti
Journal Prima Health Science Vol 1 No 1 (2019): Oktober
Publisher : LPPM STIKes Prima Indonesia

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Abstract

Self medication is the act of selecting and using drugs by someone totreat a disease or symptom that can be recognized by themselves. Thatpractice is based on the thought that self medication is sufficient totreat minor ailments without involving medical staff. But in itsimplementation there are still medication error, because of that,monitoring is needed from pharmacist. Society needs appropriateknowledge to get the right behavior in self medication. Methampyronis one of the analgetic drug from nonsteroidal antiinflammatory grups(NSAID) that are included in the apothecary medicine (OWA) no. 1.This research aims to determine the correlation between knowledgewith self medication behavior towards methampyron use inpharmacies. This research is an observational analytic study withcros sectional method approach and using a purpose samplingtechnique with 88 respondents conducted in Apr – June 2019. Theresult of this research indicate that 83% of respondents have goodknowledge and 17% of respondents have sufficient knowledge. In selfmedication behavior, the use of methampyron shows 86% ofrespondents have good rationality and 14% of respondents havesufficient rationality. Where knowledge and rationality selfmedication behavior there is a significant relationship with asignificance value of 0,016 (< 0,050). From these results, it can beconcluded that the rationality behavior is closely related to theknowledge of self medication.
Hubungan Antara Tingkat Pengetahuan Orang Tua Terhadap Pola Pengobatan Pasien Pediatri Penderita Infeksi Saluran Pernapasan Akut (Ispa) Di Puskesmas Sriamur Kabupaten Bekasi Bulan Oktober 2019 Indah Zahara; Dodi Efendi
Journal Prima Health Science Vol 1 No 4 (2020): Agustus
Publisher : LPPM STIKes Prima Indonesia

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Abstract

Acute Respiratory Infection (ARI) is a disease that often occurs in children because at the age of 3-6 months there are missing maternal antibodies and the production of antibodies themselves, infections caused by viruses and bacteria, in Indonesia the child morbidity due to ARI is 4.4%. The incidence of ARI in children can be influenced by parents' knowledge of ARI treatment patterns. Good parent’s knowledge is expected to reduce the incidence of ARI in children, as well as the correct treatment pattern can reduce the incidence of ARI in children. The purpose of this study was to determine the relationship between the level of parent’s knowledge on treatment patterns in pediatric patients suffering from ARI in Sriamur Public Health Center in Bekasi District in October 2019. The design of this study is quantitative analytic with cross-sectional approach. The sample of this study were 48 parents who had children in the working area of the Sriamur Public Health Center in Bekasi. This study uses a validated questionnaire to retrieve data from pediatric patients diagnosed with ARI, In the case of ARI, male sex is higher in ARI, which is around 26 (54.2%) with a child age <5 years of age of 32 (66.7%). From the ARI treatment pattern, the child's parents gave supporting drugs in the form of paracetamol 45 (93.8%), ibuprofen 3 (6.3%), whereas parents know 100% amoxilin type antibiotics. From the research obtained P value = 1, so there is no relationship between the level of knowledge of the treatment patterns of pediatric patients suffering from ARI. Separation of the sample is needed to get a better value.
UJI TOKSISITAS AKUT SENYAWA ASAM p-METOKSISINAMAT YANG DISINTESIS DARI ETIL p-METOKSISINAMAT Sara Nurmala; Indah Zahara
JURNAL KIMIA MULAWARMAN Vol 19 No 2 (2022)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30872/jkm.v19i2.901

Abstract

Kencur (Kaempferia galanga L.) is a plant that grows in Indonesia and is often used as a traditional spice. The main content of Kencur is ethyl p-methoxycinamic has a mild level of toxicity. Hydrolysis results from Ethyl p-methoxycinamic namely p-methoxycinamic acid have been widely studied as having antibacterial activity against S. aureus with MIC of 125 ppm. P-methoxycinamic acid has anti-inflammatory activity, topical anti-inflammatory power of 8.7% p-methoxycinamic acid based on molar equality with 1% Na-diclofenac. Cinnamic acid compounds have greater potential as an inhibitor of cervical cancer cells compared to methyl cinnamon because they have more hydrogen bonds. Hydrolysis of ethyl p-methoxycinamic to p-methoxycinamic acid has been carried out, then identification tests have been carried out covering the melting distance obtained values ​​of 172–173ºC. The results of TLC analysis with the mobile phase of methanol: acetone (2: 1) p-methoxycinamic acid compound gave an Rf value of: 0.67. The results of infrared spectrum analysis of hydrolysis compounds provide information on the presence of specific functional groups, namely carbonyl groups of acids (C = O) which are shown by the absorption band at wave number 1690.49 cm-1. Hydrogen bonding in carboxylic acid dimers weakens the C = O bond, resulting in absorption at lower wave numbers. In this spectrum CO groups of acids are shown at absorption of 1029.92 cm-1, aromatic C = C groups are shown by uptake at wave numbers 1602.74 cm-1 and 1627.81 cm-1, while bands at wave number 828.37 cm-1 indicates the presence of para-substituted aromatic nuclei. Acute toxicity test of p-methoxycinamic acid compound which was carried out in a span of 24 hours showed that p-methoxycinamic acid had a moderate level of toxicity.
The Effect of Hand Washing Soap with Soursop Leaf and Guava Leaf Extract on Staphylococcus aureus Bacteria Indah Zahara; Agustina Nina
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 8, No 2: June 2023
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30604/jika.v8i3.1969

Abstract

This study tested a handwash formulation containing a combination of soursop leaf extract and guava leaf extract as active ingredients. These two extracts are known to have antibacterial properties, and the study results show that the formulated handwash has physical and chemical properties according to SNI standards. The formulated handwash has a brown color with a distinctive aroma of extract, homogeneous, pH 10.00, foam height of 100 mm, and viscosity ranging from 700-20,000 cPs with pseudoplastic flow properties. In addition, handwashing with a combination of soursop and guava leaf extract also showed significant antibacterial activity against Staphylococcus aureus bacteria. The average diameter of the inhibition zone for handwash with different formulas showed powerful results. Thus, combining soursop leaf extract and guava leaf extract can be an effective alternative in maintaining hand hygiene and preventing disease transmission through contact with microorganisms on the hands. Further research needs to be done to optimize the use of natural ingredients such as soursop leaf extract and guava leaf extract in health care products to provide more comprehensive benefits to maintain the health and cleanliness of the body. Abstrak: Penelitian ini menguji formulasi handwash yang mengandung kombinasi ekstrak daun sirsak dan ekstrak daun jambu biji sebagai bahan aktif. Kedua ekstrak ini diketahui memiliki sifat antibakteri, dan hasil penelitian menunjukkan bahwa handwash yang diformulasikan memiliki sifat fisik dan kimia yang sesuai dengan standar SNI. Handwash yang diformulasikan memiliki sediaan berwarna cokelat dengan aroma khas ekstrak, homogen, pH 10,00, tinggi busa 100 mm, dan viskositas berkisar antara 700-20.000 cPs dengan sifat alir pseudoplastis. Selain itu, handwash dengan kombinasi ekstrak daun sirsak dan ekstrak daun jambu biji juga menunjukkan aktivitas antibakteri yang signifikan terhadap bakteri Staphylococcus aureus. Diameter rata-rata zona hambat untuk handwash dengan formula yang berbeda menunjukkan hasil yang sangat kuat. Dengan demikian, kombinasi ekstrak daun sirsak dan ekstrak daun jambu biji dapat menjadi alternatif efektif dalam menjaga kebersihan tangan dan mencegah penularan penyakit melalui kontak mikroorganisme pada tangan. Penelitian lebih lanjut perlu dilakukan untuk mengoptimalkan penggunaan bahan alami seperti ekstrak daun sirsak dan ekstrak daun jambu biji dalam produk perawatan kesehatan, guna memberikan manfaat yang lebih luas dalam upaya menjaga kesehatan dan kebersihan tubuh.
KARAKTERISASI KOMPREHENSIF NANO PARTIKEL EKSTRAK DAUN SIRSAK Indah Zahara; Effionora Anwar; Dian Ratih Laksmitawati; Deni Rahmat
Binawan Student Journal Vol. 5 No. 1 (2023)
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Binawan (LPPM Universitas Binawan)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54771/bsj.v5i1.874

Abstract

Nanoteknologi telah merevolusi berbagai bidang, termasuk kedokteran, dengan memberikan peluang baru untuk penelitian dan aplikasi. Penelitian ini berfokus pada karakterisasi nanopartikel yang berasal dari ekstrak daun sirsak. Nanopartikel disintesis menggunakan polimer kitosan dan ekstrak daun sirsak, dan sifat-sifatnya dianalisis. Hasil penelitian menunjukkan rentang ukuran partikel yang luas, dengan ukuran rata-rata 210,9 nm dan modus 161,4 nm. Nanopartikel menunjukkan potensial zeta negatif sebesar -31,5 mV, yang menunjukkan stabilitasnya dalam larutan. Efisiensi penyerapan ditemukan sebesar 87,90%, dan kapasitas muatan obat mencapai 37,92%. Mikroskop elektron pemindaian mengonfirmasi morfologi nanopartikel yang berbentuk bulat. Temuan ini menyoroti potensi nanopartikel dari ekstrak daun sirsak untuk pengiriman obat dan menekankan pentingnya karakterisasi komprehensif untuk aplikasi di masa depan.
Edukasi Masyarakat Terkait Diabetes Mellitus, Pencegahan, dan Terapi Komplementer dengan Teh Putih (Camellia sinensis L.) dan Probiotik (Lactiplantibacillus plantarum) di Desa Babelan Kota Kabupaten Bekasi: The Health Education Regarding Diabetic Mellitus, Prevention, and Complementer Therapy with White Tea (Camellia sinensis L.) and Probiotic (Lactiplantibacillus plantarum) at Desa Babelan Kota, Bekasi District Zahara, Indah; Ekayanti, Meiliza; Setiadi, Feri; Alfianna, Wiwin; Rizki, Yulia Rafitri
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 10 No. 4 (2025): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v10i4.8169

Abstract

The prevalence of Diabetes Mellitus (DM) has consistently increased and is one of the main death issues in the world due to complications. The increase in Diabetes cases in Bekasi Regency was 38% since 2020. Educational programs aim to increase awareness and reduce DM cases in Bekasi Regency. The method was direct (seminar) and indirect (media) and questionnaires to determine knowledge. The total of participants was 22 (male 55% and female 45%), and the largest age group was 46-55 years (54.5%). The average knowledge pre-education (77,3%) and post-education (81,3%) are categorized as “good”. The result of the analysis using T-test sig. value (2-tailed) obtained 0.000 (α<0,005). It was concluded there was an influence on the level of knowledge of participants pre- and post-education.
Formulasi Dan Uji Efektivitas Deodoran Roll-On Perasan Jeruk Lemon (Citrus Limon (L.)) Dalam Menghambat Bakteri Staphylococcus Epidermidis Untuk Mengurangi Bau Badan Zahara, Indah
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 5 No. 2 (2025): COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v5i2.3197

Abstract

Antioxidant Activity Cultivated of Soursop (Annona muricata L.) Leaves Extract in Jayasari Village, Pangandaran District, West Java Zahara, Indah; Anwar, Effionora; Laksmitawati, Dian Ratih; Rahmat, Deni
Journal of Natural Product for Degenerative Diseases Vol. 1 No. 1 (2023): JNPDD September
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/jnpdd.v1i1.5317

Abstract

Indonesia is a source of raw materials for tropical medicines that treat various diseases. One of the places to plant soursop leaves in West Java is Jayasari Village, Pangandaran District. Annona muricata Linn (Soursop) leaves is a medicinal plant widely used as an anti-diabetic, anti-inflammatory, insecticide, antimalarial, anticancer, antibacterial, and antioxidant. Soursop leaves have many benefits because they contain phytochemical compounds. This study aims to determine the phytochemical content, total flavonoid content, and antioxidant activity of A. muricata leaves. This research was carried out in several steps, including extraction, evaporation, phytochemical testing, total flavonoid content, and antioxidant activity. Phytochemicals were extracted with 96% ethanol by maceration. Measurement of flavonoids in extracts was determined using standard quercetin and UV-Vis spectrophotometry method. Antioxidant activity was carried out through a 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical removal test. The results showed that the ethanol extract of soursop leaves contained alkaloids, flavonoids, phenolics, saponins, and tannins. The results of measurements of flavonoids from the ethanol extract of soursop leaves showed that 1 g of the extract contained 8.32 mg of quercetin equivalent. The ethanol extract of soursop leaves has antioxidant activity, as indicated by the scavenging of DPPH radicals with an IC50 of 56.73 ppm.
Penyuluhan dan Analisis Pengetahuan Wanita Terkait Infeksi Staphylococcus aureus di Desa Babelan Kota Kabupaten Bekasi: The Health Education and Knowledge Analysis Against Staphylococcus aureus Infection of Women at Desa Babelan Kota, Bekasi District Zahara, Indah; Ekayanti, Meiliza; Amalia, Putri; Umamah, Siti
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 2 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i2.5861

Abstract

Staphylococcus aureus is a pathogen that causes various clinical manifestations; it couldn't cause skin infections in healthy people, but if it enters the bloodstream or internal tissues, it might cause serious infections. Desa Babelan Kota, Bekasi District, is a densely populated location with secondary education backgrounds. The aim of this study is to increase awareness and would impact the quality of life. The method was health education, analysis of the characteristics, and knowledge before and after education. The characteristic results of participant (n) 25 females are 17-25 years (44%) with the majority's highest education in Junior High School (52%) and High School, 19.2%. The average knowledge based on the pretest results is 74.1% (adequate), and the posttest is 85.2% (good). The Non-Parametric analysis of 2 paired samples and the Wilcoxon test obtained a significance value of 0.550 (p >0.05). It concluded that there was no significant difference in the average knowledge of respondents before and after health education.
Co-Authors Adelia Putri Agustina Nina Deni Rahmat Dian Ratih Laksmitawati Dodi Efendi Effionora Anwar Effionora Anwar Ekayanti, Meiliza Nabila Octavianti Prita Ardianti Putri Amalia RAHMAT, DENI Rizki, Yulia Rafitri Sara Nurmala Setiadi, Feri Sherly Novitasari Umamah, Siti Vani Aprilia Lestari Widayanti Wiwin Alfianna