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All Journal Buletin Farmatera Medika Kartika : Jurnal Kedokteran dan Kesehatan JURNAL ILMIAH SIMANTEK Jurnal Pandu Husada
Mourisa, Cut
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Religion Agriculture, Biological Sciences & Forestry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : Buletin Farmatera

 1 
Effect Of Low Doses of Acetylsalicylic Acid (ASA) On the Histopathological Features of Fibroblasts in The Amniotic Membrane Mourisa, Cut; Suryani, Des
Buletin Farmatera Vol 9, No 3 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v9i3.19907

Abstract

Abstract: Acetylsalicylic acid (ASA) is a drug with several indications such as analgesic, antipyretic, and antithrombotic/antiplatelet. ASA is efficacious as antithrombotic at low doses and used for thrombosis therapy in stroke, antiphospholipid syndrome (APS), pre-eclampsia and eclampsia. However, the administration of ASA made pharmacokinetic interactions that cause a vitamin C deficiency condition. This study aims to determine the effect of low doses of Acetylsalicylic acid (ASA) on the histopathological appearance of fibroblasts on fetal membranes. This study used a cross-sectional design using 54 paraffin membrane blocks as samples processed into histopathological preparations. The case group received low-dose ASA and the control group did not receive low-dose ASA. Histopathological preparations were observed using a microscope to see images / count the number of fibroblast cells. The results showed that there were significant differences between the number of fibroblasts in the case group and the control group with p = 0.001 or p 0.05
Inhibition Test of Aloe Vera Extract (Aloe vera l.) Against the growth of Staphylococcus aureus Amin Lubis, Muhammad Rizqi; Mourisa, Cut
Buletin Farmatera Vol 11, No 1 (2026)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v11i1.26486

Abstract

Abstract: The use of antibacterial is a solution to treat various infectious diseases. However, the mismatch of the dose given can lead to bacterial resistance to these antibacterial substances. So, it is necessary to renew or develop natural medicines to kill bacteria and prevent resistance. One type of plant that can be used as a natural antibacterial is aloe vera (Aloe vera L.) because it contains several active substances including saponins, flavonoids, tannins and polyphenols which are thought to have antibacterial activity. This study used an experimental method with a laboratory observation approach. The technique used to measure the extra inhibition of aloe vera (Aloe vera L.) is the well diffusion method. The results showed that aloe vera extract (Aloe vera L.) in all concentration groups (20%, 40%, 60%, 80%, and 100%) had a significant difference. with a probability value (p) 0.05, which means that aloe vera extract is effective in inhibiting the growth of Staphylococcus aureus bacteria. Aloe vera extract ( Aloe Vera L) is effective in inhibiting the growth of Staphylococcus aureus.
Co-Authors AMIN LUBIS, M. RIZQI Amin Lubis, Muhammad Rizqi Des Suryani Sukatendel, Firya Nadine Chalishny Yulsyafrida, Astriani