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All Journal Indian Journal of Forensic Medicine & Toxicology
Khalil H. Aljeboori 1 , Khalil Gzar2
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Study the Histopathogic Effects of Arsenic Trioxide on Some Parenchymatous Organs of Male Rats and Under Alphalipoic Acid Khalil H. Aljeboori 1 , Khalil Gzar2
Indian Journal of Forensic Medicine & Toxicology Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v14i4.11833

Abstract

This study was designed to evaluate the histopathogical effects of arsenic trioxide (ATO) on the some organsof rats , for this reason group of rats (15) were I/P inoculated with 1.5 mg /Kg .B.wt . daily for 30 days othergroup( 15 rat) treated with 100 mg/kg.B.wt of alphalipoic acid and ATO ( 1.5 mg/ kg.B.wt) for 30 .Theresults was revealed that the extensive pathological lesions in the liver , kidney , spleen and testes in all ratsexposed to arscenci trioxide due to the pathotoxic effect of ATO and decreased lesions were in the grouptreated with the alpha lipoic acid .100 mg / kg .B.wt) for 30 days as ameliorative or protective effect againstpathotoxicity of ATO .
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