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All Journal Indian Journal of Forensic Medicine & Toxicology
Arti D. Shah1 , Anchal Jain2 , Apoorva3 , Kusum V. Shah4 , Yash Rana5 , Saket kumar6
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Isoniazid Mono Resistance: Changing Trends in Drug Resistant Pulmonary Tuberculosis. – A Case Series of 3 Patients Arti D. Shah1 , Anchal Jain2 , Apoorva3 , Kusum V. Shah4 , Yash Rana5 , Saket kumar6
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 1 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i1.13368

Abstract

Drug resistant tuberculosis is a major public health concern in many countries including India, Isoniazidresistance (INH) accounts for 7.2 % of new cases globally.1In our case series 3 patients had INH monoresistance out of which 2 patients had no previous history anti tuberculosis therapy (ATT). All 3 patientsreceived 6 months of standard regimen under National Tuberculosis Elimination Programme (NTEP).All patients showed clinical improvement. INH mono resistance diagnosis is often delayed due to lack ofinfrastructure of 1st line probe assay (LPA) at various centres. INH mono resistance if diagnosed early canalso help in prevention of Multi drug resistant tuberculosis (MDR TB)
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