Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Paediatrica Indonesiana Jurnal Biomedika dan Kesehatan
Witarto, Andro Pramana
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Efficacy of lactose-free formula in acute diarrheal management for children under 5 years: a systematic review and meta-analysis Putri, Ayu Maghfira Nida; Witarto, Andro Pramana; Yofi, Fadhil Abiyyu; Suasti, Ni Made Adnya; Alawiyah, Kania
Paediatrica Indonesiana Vol. 64 No. 3 (2024): May 2024
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi64.3.2024.233-43

Abstract

Background Acute diarrhea is the most common gastrointestinal disease in children under five years of age with high morbidity and mortality risk. The use of lactose-free formula in the management of children with acute diarrhea was said to accelerate the diarrheal resolution time. Objective To determine the efficacy of lactose-free formula in managing acute diarrhea in pediatric patients by systematic review and meta-analysis. Methods A comprehensive literature search was conducted on PubMed, Proquest, Web of Science, and CINAHL Plus Database from November 1971 to July 11th, 2021. The study selection process was carried out under PRISMA 2020 guidelines based on several eligibility criteria. The quality of the included studies were further assessed using Modified Jadad Scores. Results Fifteen randomized controlled trials (RCTs) were included, involving a total of 1,390 children with acute diarrhea. Shorter recovery time (MD -0.21; 95%CI -0.50 to 0.08; P=0.16) was observed in patients receiving lactose-free formula than the control group. However, this finding was not statistically significant. The subgroup analysis showed that lactose-free formula significantly shortened the recovery time compared to oral rehydration solution (ORS) group (MD -0.70; 95%CI -0.98 to -0.41; P=0.00001). Furthermore, lactose-free formula also significantly reduced the amount of stool output (MD -0.61; 95%CI -0.86 to -0.36; P=0.00001) and the incidence of persistent diarrhea more than seven days (OR 0.22; 95%CI 0.10 to 0.51; P=0.0004) compared to the control group. Conclusion Lactose-free formula as dietary management for acute diarrhea in children can reduce stool output and the incidence of persistent diarrhea for more than seven days. It also may shorten the recovery time compared to the administration of ORS alone.
Mengungkap Potensi Platelet-Rich Plasma untuk Meningkatkan Kualitas Hidup Pasien dengan Nyeri Punggung Bawah: Sebuah Tinjauan Literatur Sasongko, Muhammad Gagas; Ramadhan, Dwiky Ananda; Luwito, Jeffry; Latumahina, Jonathan; Widyatmiko, Himawan; Witarto, Andro Pramana
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Low back pain (LBP) is a widespread issue that affects many people globally, causing significant limitations in daily activities and work. LBP imposes a considerable economic burden due to healthcare costs and lost productivity. This review explores platelet-rich plasma (PRP) therapy, a promising treatment because of its ability to regenerate tissues. PRP contains growth factors that stimulate cell activity and collagen production, which can significantly reduce pain and enhance mobility and quality of life for LBP sufferers. PRP's capacity to aid in tissue repair and decrease inflammation suggests it could be beneficial for these various causes. Compelling clinical studies have demonstrated that PRP can dramatically reduce pain and disability, offering patients renewed hope and improved outcomes. Additionally, PRP therapy is minimally invasive with rare and mild side effects, underscoring its safety and efficacy. This review underscores the urgent need for further research to refine PRP treatment protocols and confirm long-term benefits. Large-scale randomized controlled trials are essential to develop standardized guidelines and ensure consistent, positive results across diverse patient populations. PRP therapy represents a revolutionary approach to managing LBP, promising to address the root causes and deliver lasting relief rather than merely masking symptoms. The future of LBP treatment could be significantly improved through the widespread adoption of PRP therapy.
Co-Authors Alawiyah, Kania Latumahina, Jonathan Luwito, Jeffry Putri, Ayu Maghfira Nida Ramadhan, Dwiky Ananda Sasongko, Muhammad Gagas Suasti, Ni Made Adnya Widyatmiko, Himawan Yofi, Fadhil Abiyyu