Indrawati, A.
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IMPROVING SOCIAL MEDIA LITERACY TO COLLEGE STUDENTS ABOUT COVID-19 HEALTH PROTOCOLS THROUGH VIRTUAL CLASSROOMS Haris, Risma; Suriati, Suriati; Rahmawati, Rahmawati; Indrawati, A.; Warda, Warda; Rizal, Faisal
JMM (Jurnal Masyarakat Mandiri) Vol 5, No 2 (2021): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3573.92 KB) | DOI: 10.31764/jmm.v5i2.4178

Abstract

Abstract:  This community service (PKM) focuses on improving students' social media literacy skills through virtual classroom-based learning at PPs UIT Public Health. This determination of increasing social media literacy skills is motivated by the low level of social media literacy skills and information media design among students. In addition, the massive spread of Covid-19 protocol information in the community as well as the new phenomenon of social media users that increased during the pandemic. The goals achieved by this PKM: 1) improve social media literacy skills and information media design among students through virtual classroom-based learning activities 2) invite social media design practitioners as guest lecturers to share knowledge, 3) provide work experience for lecturers and students, 4) design the covid-19 health protocol information media. The method used is through lectures and demonstrations. Demonstration related materials were delivered through interactive dialogue. Furthermore, it is carried out with media design practices and uploaded to social media. This PKM produces health promotion product outcomes. Some of the components that have been achieved include: 1) achievement of the goals of PKM activities, 2) achieving the target material that has been compiled, 3) producing a media design for the Covid-19 health protocol information which is then shared on social media.Abstrak: Pengabdian kepada masyarakat (PKM) ini berfokus pada peningkatan keterampilan literasi media sosial mahasiswa melalui pembelajaran berbasis virtual classroom di Kesehatan Masyarakat PPs UIT. Penentuan peningkatan kemampuan literasi media sosial ini dilatarbelakangi oleh masih rendahnya kemampuan literasi media sosial dan desain media informasi di kalangan Mahasiswa. Selain itu, penyebaran informasi protokol covid-19 dimasyarakat yang masif serta fenomena baru pengguna media sosial yang meningkat di masa pandemi. Tujuan yang dicapai PKM ini : 1) meningkatkan kemampuan literasi media sosial dan desain media informasi di kalangan mahasiswa melalui kegiatan pembelajaran berbasis virtual classroom 2) mendatangkan praktisi desain media sosial sebagai dosen tamu untuk sharing ilmu, 3) memberikan pengalaman kerja untuk dosen dan mahasiswa, 4) membuat desain media informasi protokol kesehatan covid-19. Metode yang digunakan adalah melalui ceramah dan demonstrasi. Materi-materi terkait demonstrasi disampaikan melalui dialog interaktif. Selanjutnya dilaksanakan dengan praktik desain media dan diupload ke media sosial. PKM ini menghasilkan outcome media promosi kesehatan. Beberapa komponen yang berhasil dicapai diantaranya: 1) ketecapaian tujuan kegiatan PKM berdasarkan evaluasi terlaksana 70%, 2) tercapainya target materi yang telah susun berdasarkan evaluasi terlaksana 75%, 3) menghasilkan desain media informasi protokol kesehatan Covid-19 yang selanjutnya dishare ke media social berdasarkan evaluasi terlaksana 90%.
Potential of Neuraminidase from Pasteurella multocida for Inhibiting Avian Influenza Virus Subtype H9N2 Replication In Ovo Poetri, O. N.; Nugroho, C. M. H.; Silaen, O. S. M.; Kurnia, R. S.; Krisnamurti, D. G. B.; Indrawati, A.; Hikmah, N.; Hariyadi, I. P. P. K.; Putra, M. A.; Soebandrio, A.
Tropical Animal Science Journal Vol. 46 No. 4 (2023): Tropical Animal Science Journal
Publisher : Faculty of Animal Science, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5398/tasj.2023.46.4.487

Abstract

In recent decades, neuraminidase/sialidase-based antivirals have been produced to suppress respiratory viral infections, including avian influenza, which relies on sialic acid as the entry point for viruses into cells. While neuraminidase has been extensively studied as an antiviral agent, numerous neuraminidases still have not been evaluated for their antiviral activities. Among these is NanB neuraminidase derived from Pasteurella multocida, which has received limited research attention. This study aimed to assess the potential of NanB neuraminidase in inhibiting H9N2 avian influenza virus infection in ovo. The research commenced with the molecular re-identification of the H9N2 A/Layer/Indonesia/WestJava-04/17 virus isolate, followed by determining the EID50 through Rapid HA test results. The toxicity of NanB neuraminidase was assessed by administering various doses to embryonated chicken eggs (ECE). The antiviral activity of NanB neuraminidase on ECE was evaluated through challenge tests, including treatment before, during, and after the challenge. The assessment involved monitoring the time of embryo death, virus titer through HA test, and viral copy number via RT-qPCR. The results indicated that the H9N2 virus titers capable of infecting 50% of ECE amounted to 108.83 EID50/mL. A dose of 0.258 U/mL of NanB neuraminidase was found to be toxic, leading to embryo mortality after 48 hours of incubation at 37 ℃, while a non-toxic dose was determined to be 0.129 U/mL. The post-challenge treatment group exhibited the most significant reduction in virus titer in ECE. Notably, NanB neuraminidase derived from P. multocida demonstrated the ability to inhibit H9N2 avian influenza virus infection in the ovo model, with the optimal dosage of 0.129 U/mL. The observed decrease in virus titers in the hemagglutination assay and viral copy number assays suggests that NanB neuraminidase holds promise as a potential antiviral candidate for therapeutic approach.