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All Journal Jurnal Kedokteran Jurnal Syntax Fusion : Jurnal Nasional Indonesia KESANS : International Journal of Health and Science
Didar Haq, Abiyyu
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Chemistry Education Engineering Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Physics Public Health Social Sciences

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Potensi Sirih Gading (Epipremnum aureum) dan Lili Paris (Chlorophytum comosum) Sebagai Sarana Fitoremediasi PM2.5 di Dalam Ruangan Didar Haq, Abiyyu; Rahim, Aulia Riezka; Rahayu, Luh Ade Dita
Jurnal Kedokteran Vol 10 No 1 (2021): volume 10 nomor 1 2021
Publisher : Faculty of Medicine Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jku.v10i1.425

Abstract

92% of world population breathe dirty air because of high concentration of air pollutant. Air pollutant contributed in 43% of all Chronic Obstructive Pulmonary Disease (COPD). Particulate Matter 2.5 (PM2.5), the most dangerous component of air pollutant, has caused 4,2 million death in 2017. PM2.5 is classified into indoor PM2.5 and outdoor PM2.5. Outdoor PM2.5 has a higher average concentration than indoor PM2.5 therefore it is possible that outdoor PM2.5 influence the indoor PM2.5. Remediation is an effort to restore the air from any pollutant. Remediation technique that often used is using chemical to absorp, filtrate, ozonise, and photolyse. Phytoremediation is a remediation that utilize the surface characteristic of plants part and microorganism in the plant phyllosphere. Sirih gading (Epipremnum aureum) and lili paris (Chlorophytum comosum) has been proven to have a surface characteristic that are very effective in accumulating PM2.5. Beside that, microorganism in both of the plant’s phyllosphere are known to be able to detoxify PM2.5. Microorganism that have the ability to detoxify PM2.5 in Epipremnum aureum’s phyllosphere is Aspergillus niger, Aspergillus fumigatus, and Firmicutes bacteria. In other hands, microorganism in Chlorophytum comosum that has that ability to detoxify is Proteobacteria phyla.
Efek Neuroprotektif Ceftriaxone Dengan Meningkatkan Ekspresi GLT-1 Pada Cidera Kepala: Sebuah Kajian Sistematis Anggia Azzahra Halba, Baiq; Didar Haq, Abiyyu; Firdiansari, Alifia; Sagita Novendi, Harie
Jurnal Syntax Fusion Vol 2 No 01 (2022): Jurnal Syntax Fusion: Jurnal Nasional Indonesia
Publisher : CV RIFAINSTITUT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/fusion.v2i01.129

Abstract

Cidera otak atau cidera kepala merupakan kasus trauma ketiga paling sering ditemukan di indonesia dengan prevalensi sebesar 11,9% pada tahun 2018. Kerentanan terhadap infeksi yang meningkat pada kebanyakan kasus cidera otak membuat penggunaan antibiotik menjadi sangat masuk akal pada kasus – kasus tersebut. Salah satu antibiotik yang memiliki kemampuan penetrasi sawar darah-otak yang terbukti sangat baik adalah ceftriaxone. Baru – baru ini, mulai dilakukan penelitian yang membahas tentang efek neuroprotektif dari ceftriaxone terhadap cidera otak yaitu meningkatkan ekspresi GLT-1 yang menguatkan rasional pemberian ceftriaxone pada kasus cidera otak. Namun, belum ada kajian mengenai efektivitasnya belum ditemui. Tujuan dari penulisan artikel ini adalah untuk mengevaluasi efektivitas pemberian ceftriaxone terhadap peningkatan kadar GLT-1 pada kasus cidera otak. Metode penulisan dilakukan dengan kajian sistematik menelusuri berbagai pusat data daring mengikuti alur dan kaidah pencarian PRISMA guna mencari studi-studi yang menguji kemampuan dari ceftriaxone dalam meningkatkan kadar GLT-1 pada kasus cidera otak. Kajian ini melibatkan 5 studi inklusi dari total 722 studi dengan total subjek sebanyak 362 sampel. Berdasarkan studi inklusi tersebut, didapatkan bahwa Pemberian ceftriaxone (200mg/kgBB) terbukti efektif dalam meningkatkan kadar GLT-1 1-7 hari post-trauma jika dibandingkan dengan kelompok kontrol. Edema serebral juga mengalami perbaikan pada kelompok yang diberikan ceftriaxone jika dibandingkan dengan kelompok kontrol. Selain itu, didapatkan juga peningkatan kemampuan pembelajaran dan daya ingat post-trauma pada kelompok intervensi. Tidak ada efek samping signifikan yang dilaporkan
Poteng Local Food Potential with isolate Lactobacillus Plantarum in Preventing Depression Nurhayati, Putri; Sulthan Ardhi P.F, Muhammad; Didar Haq, Abiyyu
Jurnal KESANS : Kesehatan dan Sains Vol 1 No 3 (2021): KESANS : International Journal of Health and Science
Publisher : Rifa'Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54543/kesans.v1i3.31

Abstract

Depression is a global problem whose symptoms are easier to observe than cure. With a fairly high prevalence in Indonesia, which is up to 6.1% in 2018, this problem practically does not only affect the sufferer but also has an impact on the people around him which in turn will further reduce the quality of life of the sufferer. Lombok Island has a local food called poteng which is the result of fermented sticky rice. Poteng is able to act as a probiotic because it contains Lactobacillus plantarum. Probiotics can play a role in helping people with depression with the Gut Brain Axis mechanism by reducing Interleukin-6, increasing gamma-Aminobutyric Acid, and influencing Vitamin D and its receptors. In a depressed state, Interleukin-6 was observed to increase whereas GABA was observed to decrease. The Gut Brain Axis mechanism affects depression through neuroanatomical pathways, regulation of microbial metabolites (Short-Chain Fatty Acid), Tryptophan metabolism, and Immune Regulation.
Co-Authors Anggia Azzahra Halba, Baiq Firdiansari, Alifia Nurhayati, Putri Rahayu, Luh ade dita Rahim, Aulia Riezka Sagita Novendi, Harie Sulthan Ardhi P.F, Muhammad