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Peroksidasi Lipid dan Stress Oksidatif pada Preeklampsia Setiawan, Bambang; Insani, Dina Aulia
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 4, No 2 (2004)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v4i2.1747

Abstract

Preeclampsia is a pregnancy complication which idiopathic case. One of research topic about preeclampsia explains that preeclampsia caused by en¬dothelial dysfunction. In fact, endothelial dysfunction linked with lipid peroxidation. Lipid peroxidation happens in plasma and placenta. Lipid peroxidation consist of three steps, they are initiation, propagation, and termi¬nation. Lipid peroxidation can initiate by Reactive Oxygen Species and cata¬lyzed by metal. Beside that, lipid peroxidation can initiate oxidative stress.Preeklampsia merupakan komplikasi kehamilan dengan penyebab yang belum jelas. Salah satu kajian penelitian tentang penyebab preeklampsia menerangkan bahwa preeklamsi disebabkan oleh difungsi endotel. Disfungsi endotel ternyata berkaitan dengan peroksidasi lipid. Peroksidasi lipid terjadi di dalam plasma maupun plasenta. Peroksidasi lipid terdiri atas tiga tahap yakni inisiasi, propagasi dan terminasi. Peroksidasi lipid dapat diinisiasi oleh Senyawa Oksigen Reaktif serta dikatalisis oleh logam. Selain itu, peroksidasi lipid juga dapat mencetuskan stress oksidatif.
Implementation of Saliling Policy as Fulfillment of The Right to Health Services for People with Mental Disorders in Preventing Shackling in South Kalimantan Province Insani, Dina Aulia; Simandjutak, Marcella Elwina; Dhanardhono, Tuntas
Soepra Jurnal Hukum Kesehatan Vol 10, No 2: Desember 2024
Publisher : Universitas Katolik Soegijapranata Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24167/sjhk.v10i2.11780

Abstract

Mental health is a basic human right for every citizen without exception. In Indonesia, psychiatric hospitals are still uneven, as are the psychiatrists and health workers specialized in mental health. Mental health services and the rights of patients with mental illnesses are still not optimal, as a result, many patients with mental illnesses experience shackles. Sambang Lihum Psychiatric Hospital initiated the public service innovation program, namely Saliling (Sambang Lihum Keliling).  The purpose of this study is to determine the regulation and implementation of the Saliling policy as the fulfillment of mental health service rights in South Kalimantan Province, explore the implementation in preventing and reducing shackling, as well as inhibiting policy. The research method used is descriptive-analytic with a sociological juridical approach that examines Sailing policies.The study concludes that legal protection of patients mental illness right to health services and prevention of shackling through Saliling policies can be fulfilled. The legal basis for the right to mental health services and shackling prevention is the health law and the Minister of Health Regulation. The main inhibiting factor is the amount of budget, human resources, and program schedule.Abstrak: Kesehatan merupakan hak dasar bagi setiap warga negara tanpa terkecuali termasuk kesehatan jiwa. Jumlah fasilitas kesehatan tingkat lanjut terutama rumah sakit jiwa (RSJ) masih tidak merata di Indonesia, begitu pula dengan jumlah dokter spesialis kedokteran jiwa. Belum optimalnya pelayanan kesehatan jiwa dan belum terjaminnya hak ODGJ dapat mengakibatkan kasus Pasung. RSJ Sambang Lihum menggagas Program inovasi pelayanan publik yaitu Saliling. Program inovasi Saliling RSJ Sambang Lihum ditetapkan sebagai program untuk memberikan pelayanan kesehatan jiwa langsung pada masyarakat yang membutuhkan dan dilaksanakan untuk mencegah pasung.Tujuan penelitian ini untuk mengetahui pengaturan dan implementasi kebijakan Saliling sebagai pemenuhan hak pelayanan kesehatan bagi ODGJ di Provinsi Kalimantan Selatan, mengetahui dan mengeksplorasi implementasi kebijakan dalam mencegah dan mengurangi Pasung, serta mengetahui faktor-faktor penghambat maupun pendukung. Metode pendekatan yuridis sosiologis yang mengkaji implementasi Kebijakan Saliling.Hasil penelitian menunjukkan secara nasional pengaturan dan kebijakan pemenuhan hak pelayanan kesehatan bagi ODGJ telah ada. Perlindungan hukum terhadap pasien terutama ODGJ untuk mencegah pasung, RSJ Sambang Lihum secara khusus telah mengeluarkan Kebijakan Saliling. Kebijakan ini melibatkan lintas sektor sehingga dapat memenuhi jangkauan pelayanan kesehatan jiwa dalam rangka mencegah pasung. Kendala yang masih menjadi faktor penghambat utama adalah pada faktor teknis yaitu jumlah anggaran, SDM dan waktu pelaksanaan
Implementasi Komite Pengendalian dan Pencegahan Resistensi Antimikroba dalam Perspektif Hukum Kesehatan di RSUD Ulin Banjarmasin: Implementation of The Antimicrobial Stewardship Comittee to Prevent Antibiotic Resistance: A Health Law Perspective at Ulin Hospital Banjarmasin Pasaribu, Munawaroh; Noor Rahman, Aditya; Insani, Dina Aulia
Jurnal Hukum dan Etika Kesehatan VOLUME 5 NO 2
Publisher : Magister Ilmu Hukum - Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/jhek.v5i2.256

Abstract

This study emphasizes the relationship between legal aspects and health policy implementation, particularly the Antimicrobial Resistance Control and Prevention Program (PPRA) based on Ministry of Health Regulation No. 8 of 2015 and No. 28 of 2021. The program represents the hospital’s legal responsibility to ensure the right to safe, high-quality, and rational healthcare. Antimicrobial resistance, which increases patient morbidity and mortality, has become a global and national problem. This research employs a juridical-empirical method with a sociological approach, combining primary data from interviews with PPRA administrators and secondary data from legal documents and hospital policies. The results indicate that antibiotic use at Ulin Regional Hospital, Banjarmasin, has been regulated according to the PPRA guidelines established by the hospital director. However, implementation remains suboptimal, particularly in planning, supervision, and healthcare workers’ understanding of rational antibiotic use. The lack of management support and coordination serves as a major obstacle. Strengthening hospital information systems, managerial support, and active involvement of all health professionals are essential to ensure the sustainability of PPRA. From a health law perspective, PPRA implementation at Ulin Hospital has not fully met the principles of legal governance in healthcare. Strengthening internal regulations, enhancing managerial oversight, and conducting periodic evaluations based on the patient safety principle are required to improve compliance and service quality.