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All Journal Medical Journal of Indonesia The International Journal of Medical Science and Health Research
Leo, Henry
Unknown Affiliation
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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The Analysis Study of Risk Factor, Management and Outcome of Obesity in Children: A Comprehensive Systematic Review Saleh, Hendra; Pasambo, Trisnawanta Asih; Leo, Henry
The International Journal of Medical Science and Health Research Vol. 3 No. 2 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/65938343

Abstract

Background: Overweight and obesity under 18 years of age has been linked to an increased risk of premature mortality from middle adulthood onward. The aim: The aim of this study to show about risk factor, management and outcome of obesity in children. Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: the broad principle of treatment is to adjust the chronically positive energy balance. While lifestyle and behavior modifications with dietary changes and increased physical activity are the integral part of obesity management, the efficacy and sustainability are limited, especially for those with severe obesity. With emerging evidence on new pharmacological agents, it is hoped that obesity management in children could be improved in the future.
Central line-associated bloodstream infection related with umbilical vein catheterization and peripherally inserted central catheter in preterm infants: a meta-analysis and systematic review Sandinirwan, Indra; Leo, Henry; Muslim, Bani; Hasanah; Karina, Permata Putri
Medical Journal of Indonesia Vol. 32 No. 4 (2023): December
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.237071

Abstract

BACKGROUND Central line-associated bloodstream infection (CLABSI) is a serious complication in preterm infants undergoing catheterization, including umbilical vein catheterization (UVC) and peripherally inserted central catheter (PICC) placement. This study aimed to compare the occurrence rate of CLABSI in preterm infants associated with UVC and PICC. METHODS We conducted a systematic review and meta-analysis of studies published from 2000 to 2023 using a random effects model from 3 databases (PubMed, ScienceDirect, and Google Scholar). This study was registered with PROSPERO (CRD42023416471). RESULTS Of 10 articles included in the systematic review, 2 were randomized controlled trials, 3 were prospective studies, and the rest were retrospective. A total of 3,962 UVCs and 2,922 PICCs were incorporated in the meta-analysis. The incidence rate of CLABSI in the UVC group was lower than that in the PICC group (1.23 versus 3.03 per 1,000 catheter days). However, the odds of developing CLABSI for infants with a UVC compared to those with a PICC were not statistically significant (odds ratio: 0.88, 95% confidence interval: 0.54–1.42). CONCLUSIONS UVCs had a lower incidence rate of CLABSI than PICCs. Therefore, additional prospective studies are required to confirm these results.
Co-Authors Hasanah Karina, Permata Putri Muslim, Bani Pasambo, Trisnawanta Asih Saleh, Hendra Sandinirwan, Indra