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All Journal JURNAL FARMASIMED (JFM) JIFI (Jurnal Ilmiah Farmasi Imelda)
Siagian, Hartika Samgryce
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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FORMULASI DAN EVALUASI PEMBUATAN PRODUK NUTRASETIKAL SIRUP DARI EKSTRAK BUAH JERUK KUKU HARIMAU (Citrus medica L.) SERTA UJI AKTIVITAS ANTIOKSIDANNYA DENGAN MENGGUNAKAN METODE DPPH (2,2-DIFENIL-1-PIKRILHIDRAZIL) Gultom, Roby; Gulo, Septi Kristina; Siagian, Hartika Samgryce
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 7 No. 1 (2023): Vol. 7 No. 1, September Tahun 2023
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v7i1.1501

Abstract

Syrup nutraceutical product has been made from the fresh extract of Tiger Nails fruit (Citrus Medica L). This research is a laboratory experimental. Fresh extracts were divided into FI (10%), FII (20%) and FIII (40%). The formulations were compounds of extracts, sugars and waters. Organoleptic’s test results were color is yellow, orange’s aroma, sweet taste and thick textures. Hedonic’s test showed the color of Formulations were not like by panelists (60%) and aroma test of FII showed panelists like it (60%). The texture test of formulations showed the panelists like it (70%) and the taste test of FI showed the panelists were very like it (70%). The pH values were ranged from 4-5. The fastest dissolving time test showed from FI (8 seconds). The highest viscosity test was showed by FII (6,08 poise). The determination of vitamin C levels using UV-Vis Spectrophotometry showed FIII the highest levels of vitamin C (0.828%). But all antioxidants activity had low activity. FIII has the highest IC50 value (454172,74 ppm). Anova test value showed 0,1505>0.05 that means the antioxidant activity were not significantly different. Tukey test showed the comparison of antioxidant properties between the formulations groups showed a significance value of 0,135 > 0.05.
PEMANFAATAN MORINGA OLIEFERA DAN ESSENTIAL OIL MENJADI MASKER PEEL OFF KESEHATAN KULIT WAJAH DENGAN KONSEP ECOFRIENDLY Samosir, Sri Rezeki; Elnovreny, Jane; Siagian, Hartika Samgryce; Mardiah, Ainun
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 8 No. 1 (2024): Vol. 8 No. 1, September Tahun 2024
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v8i1.1745

Abstract

A peel-off mask cosmetic product has been made from the ethanol extract of the leaves of the Moringa oliefera plant. The research method is experimental. Moringa leaf extract was obtained by the maceration method using 75% ethanol solvent. The extract is divided into six formulations, namely FI (0.5%), FII (1%), FIII (1.5%) and FIV (0.5%), FV (1%), FVI (1.5%) . The formulation for making peel off mask products uses a mixture of green tea essential oils (FIV, FV, FVI). Evaluation of Peel Off mask product preparations consists of organoleptic tests, homogeneity tests, pH tests, Hedonic tests, Irritation tests, spreadability tests. Based on the results of organoleptic tests, non-essential oil preparations in FI have a yellow color, FII has a brown color, and FIII has a brown color, where all three formulations have the aroma of Moringa leaves, while the formulation with the addition of essential oil in FIV has a white color, FV has a brown color, and FVI Brown in color, all three formulations have the aroma of green tea essential oil. The homogeneity test results of all formulations have a homogeneous texture and have a pH of 7. The hedonic test uses 10 panelists to determine the panelists' level of preference. The hedonic test results for color are 40% FI, 50% FII, 60% FIII, 100% FIV, 90% FV and 90% FVI. The hedonic test for texture is 50% FI, 60% FII, 50% FIII, 80% FIV, 100% FV, and 90% FVI. The hedonic test for aroma obtained 20% FI, 40% FII, 50% FIII, 80% FIV, 90% FV and 90% FVI. The Moringa leaf extract peel off mask does not cause irritation to the skin and has a spreadability of around 3.9 – 6.2 cm.
The Influence of Abdominal Circumference and Body Mass Index On Hypertension anggraeni, Ratih; Marbun, Romauli Anna Teresia; Siagian, Hartika Samgryce; Lubis, Amelia Hasana
Jurnal FARMASIMED (JFM) Vol 7 No 1 (2024): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v7i1.2358

Abstract

The Body Mass Index (BMI) value is used to determine the body composition value, calculated using a formula involving height and weight. Increasing body weight will affect the size of the stomach circumference. One indicator of BMI that can identify the risk of morbidity due to increased body weight is the measurement of the size of the abdominal circumference. If there is an increase in BMI, the risk of developing hypertension and other heart diseases also increases. Hypertension is when a person's blood pressure exceeds normal (120/80mmHg). This research was conducted to analyze the influence of BMI and abdominal circumference on hypertension symptoms using analytical observation. Random sampling was taken from the USU Faculty of Medicine student population with the criteria of having a history of heart disease, a history of metabolic disease, taking heart medication, and being an athlete. Respondents had their height and weight measured, their BMI values were calculated, then their abdominal circumference, and their blood pressure. The results showed that there was an influence between BMI and abdominal circumference on symptoms of hypertension. There was a significant correlation between BMI and systole (p=0.000) and diastole (p=0.014) as well as a moderate correlation coefficient for systole (r=0.466) and diastole (r=0.340). There is a correlation between abdominal circumference and systole (p=0.000) and diastole (p=0.038) and a moderate level correlation coefficient with systole (r=0.480) and diastole (r=0.289). It can be concluded that there was an influence of BMI and LP on hypertension.
Co-Authors Ainun Mardiah Elnovreny, Jane Gulo, Septi Kristina Gultom, Roby Lubis, Amelia Hasana Ratih Anggraeni Samosir, Sri Rezeki