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All Journal Indonesian Chimica Letters Journal of Innovative and Creativity
Fauziah, Dina Trianggaluh
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Chemistry Education Languange, Linguistic, Communication & Media Mathematics Social Sciences Other

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The Volatile Compound Profiles of Fire-Cured and Fermented Na-Oogst Tobacco Leaves (Nicotiana tabacum L.) and Its In-Silico Study Oktavianawati, Ika; Wulandari, Ulfa; Winata, I Nyoman Adi; Ridho, Atok Ainur; Kedang, Yohana Ivana; Fauziah, Dina Trianggaluh; Yusro, Fatimah
Indonesian Chimica Letters Vol. 4 No. 1 (2025)
Publisher : Department of Chemistry, Faculty of Mathematics and Natural Sciences, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/icl.v4i1.5995

Abstract

Na-Oogst tobacco is one of the local commodities of Jember, which has been widely used as a raw material for making cigarettes. Product diversification in processing tobacco leaves is very necessary to reduce the danger caused by cigarette consumption. It is also an effort to empower and save the economy of tobacco farmers. Tobacco leaf’ essential oil could be an alternative in maintaining tobacco production. The purpose of this study is to determine the profile (yield and chemical compounds) of Na-Oogst tobacco leaf essential oil content in pre- and post-fermentation. Extraction of essential oils is carried out by two methods, i.e., steam distillation and maceration. The results showed that the extraction from the maceration method produced higher yields than from steam distillation, while the extract from tobacco leaves before fermentation was lower than that after fermentation. The major identified compounds found in tobacco leaves from GC-MS analysis are neophytadiene, nicotine, ledol, phytol, and solanone. Neophytadiene is suggested as a marker compound in tobacco leaf since it is present in all extracts and essential oils in significant amounts, about 23.72-67.37% of the total identified compounds. Further molecular docking of neophytadiene against the D2 dopamine receptor is also investigated in this study.
Uji Stabilitas Siklik Hair Growth Tonic Seledri (Apium Graveolens L.) Celery (Apium Graveolens L.) Hair Growth Tonic Cycling Test Soleh, Ayu Angger Putri M.; Frissanty, Mery Dian; Isnawati, Nafisah; Fauziah, Dina Trianggaluh
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.6967

Abstract

Kerusakan rambut akibat kebiasaan harian, lingkungan, dan kondisi kesehatan mendorong permintaan tonik penumbuh rambut yang aman, namun bahan sintetis seperti minoxidil berisiko menyebabkan alergi dan sakit kepala. Apigenin dari seledri (Apium graveolens L.) menjadi alternatif alami. Penelitian ini bertujuan menganalisis perbedaan stabilitas siklik hair growth tonic ekstrak daun seledri konsentrasi 4%, 9%, dan 14%. Penelitian eksperimental kuantitatif pra-post test menggunakan tiga formula tonik 100 ml sebagai sampel purposif. Instrumen meliputi pH meter, viskometer, piknometer, dan SPSS 25 untuk uji normalitas Shapiro-Wilk diikuti uji Wilcoxon/T-paired (Sig >0,05). Hasil menunjukkan tidak ada perubahan signifikan parameter fisikokimia (karakteristik fisik, ketersebaran zat aktif, pH 3-7, densitas <1 g/ml) selama 6 siklus pada semua formula, meskipun konsentrasi 14% melebihi batas viskositas (7,7 cPs >5 cPs) siklus ke-3. Konsentrasi lebih tinggi menurunkan pH, meningkatkan densitas dan viskositas. Kesimpulannya, konsentrasi 4% dan 9% menunjukkan stabilitas siklik sangat baik, mendukung pengembangan kosmetik herbal.
Co-Authors Frissanty, Mery Dian I Nyoman Adi Winata Ika Oktavianawati Kedang, Yohana Ivana nafisah isnawati Ridho, Atok Ainur Soleh, Ayu angger Putri M. Wulandari, Ulfa Yusro, Fatimah