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All Journal Media Gizi Kesmas Indonesian Journal of Perinatology
Darmawan, Ernawati
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Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences

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Faktor Risiko Hasil Janin/Bayi pada Wanita Hamil dengan Kanker di Jawa Timur Indonesia: Studi Epidemiologi Naoum, Nardeen Adel Mekhail; Darmawan, Ernawati
Media Gizi Kesmas Vol 12 No 1 (2023): MEDIA GIZI KESMAS (JUNI 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i1.2023.277-284

Abstract

Background: Cancer during pregnancy is a rare event, despite its rarity, its incidence nowadays keeps on increasing worldwide. Objective: This study aims to describe the available data on pregnant women with cancer in East Java- Indonesia, maternal outcomes and fetal outcomes, and knowing the risk factors of bad fetal outcomes in pregnant women with cancer from an epidemiological point of view. Method: This is a quantitative observational study of pregnant women with cancer in East Java Indonesia. Its design is a Cross-sectional study. Data collection was obtained from secondary data (the medical report in the Obgyn department at Dr. Seotomo Hospital from 2016 – 2020). Data were analyzed statistically by using SPSS program version 25. Result: The results showed that from 2016 to 2020, 54 cases of pregnant women with cancer had been extracted with an incident rate 0.8%. The incident rate of Non-Obgyn Cancer (55.6%) is higher than Obgyn Cancer (44.4%). The highest incident rates in non-Obgyn Cancer are Breast cancer (7.5%) and Leukemia (3.7%), while the highest incident rates in Obgyn Cancer are Cervical and Ovarian (8.4%). There was no relationship between cancer type and fetal outcomes, while there is a relationship between cancer stage and fetal outcomes. Conclusion: Cancer stage could be risk factor for fetal outcomes in Indonesian pregnant women with cancer.
Water Birth as Neuroendocrine Medicine: A Critical and Integrative Review of Hormonal and Psychophysiological Impacts on Maternal and Neonatal Outcomes Sanjaya, I Nyoman Hariyasa; Andonotopo, Wiku; Dewantiningrum, Julian; Pramono, Mochammad Besari Adi; Mulyana, Ryan Saktika; Pangkahila, Evert Solomon; Akbar, Muhammad Ilham Aldika; Yeni, Cut Meurah; Aldiansyah, Dudy; Bernolian, Nuswil; Wiradnyana, Anak Agung Gede Putra; Darmawan, Ernawati; Stanojevic, Milan; Kurjak, Asim
Indonesian Journal of Perinatology Vol. 6 No. 2 (2025): Available online : 1 December 2025
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v6i2.79

Abstract

Background: Water birth, defined as labor and/or delivery conducted in warm water, has gained increasing recognition as a patient-centered and physiologically supportive birth practice. Beyond analgesia, growing evidence indicates that water immersion during labor modulates maternal neuroendocrine regulation, psychological well-being, and neonatal physiological adaptation. Nevertheless, these hormonal and psychophysiological mechanisms remain insufficiently integrated into conventional perinatal research and clinical frameworks. This review aims to synthesize current evidence on the neuroendocrine, psychophysiological, obstetric, and neonatal effects of water birth and to evaluate its clinical effectiveness and safety in low-risk pregnancies. Methods: An integrative review was conducted using a PRISMA-guided approach to identify peer-reviewed studies published between 2000 and 2025. Literature searches retrieved 3,287 records from major biomedical databases, of which 44 studies (12 randomized controlled trials, 19 cohort studies, 6 case–control studies, and 7 systematic reviews) met inclusion criteria. Data were synthesized thematically, focusing on maternal hormonal responses (oxytocin, β-endorphins, cortisol, prolactin), labor outcomes, breastfeeding, postpartum mood, neonatal adaptation, and safety considerations. Results: Across study designs, water immersion during labor was associated with increased endogenous oxytocin and β-endorphin activity and reduced stress-related hormonal responses. Clinically, first-stage labor was shortened by approximately 42–78 minutes, and epidural analgesia use was reduced by 30–50% compared with conventional land birth. Episiotomy rates were generally below 5%, and maternal satisfaction scores were consistently higher. Early breastfeeding initiation occurred in 86–92% of water birth cases, with exclusive breastfeeding rates at six weeks ranging from 66–77%. Neonatal outcomes, including 5-minute Apgar scores and NICU admission rates, were comparable to or slightly better than conventional birth in low-risk populations, with no consistent increase in infection or respiratory complications when standardized protocols were applied. Conclusion: Water birth supports a hormonally optimized and psychologically protective labor environment, with measurable benefits for labor efficiency, maternal experience, breastfeeding success, and neonatal physiological transition. When implemented under evidence-based guidelines, it represents a credible non-pharmacological option within contemporary, physiology-informed maternity care.
Co-Authors Aldiansyah, Dudy Aldika Akbar, Muhammad Ilham Andonotopo, Wiku Cut Meurah Yeni Evert Solomon Pangkahila I Nyoman Hariyasa Sanjaya Julian Dewantiningrum Kurjak, Asim Naoum, Nardeen Adel Mekhail Nuswil Bernolian Pramono, Mochammad Besari Adi Ryan Saktika Mulyana Stanojevic, Milan Wiradnyana, Anak Agung Gede Putra