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All Journal BALI MEDICAL JOURNAL (BMJ) Medicina E-Jurnal Medika Udayana E-Jurnal Udayana Medica WMJ (Warmadewa Medical Journal) JNKI (Jurnal Ners dan Kebidanan Indonesia) (Indonesian Journal of Nursing and Midwifery) Indonesian Journal of Obstetrics & Gynecology Science ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Ilmiah Sangkareang Mataram Indonesian Journal of Perinatology Public Health and Preventive Medicine Archive Journal Research of Social Science, Economics, and Management Journal of Global Pharma Technology
I Nyoman Hariyasa Sanjaya
Department Of Obstetrics And Gynecology, Faculty Of Medicine, Udayana University
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Economics, Econometrics & Finance Education Environmental Science Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Other

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GROUP-B STREPTOCOCCUS IN PREGNANT WOMEN: Prevalence of Colonization and Sensitivity Pattern in Denpasar during June 2007?May 2008 Sri-Budayanti,, N; Hariyasa-Sanjaya, and, N
BALI MEDICAL JOURNAL Volume 2 Number 1, January-April 2013
Publisher : BALI MEDICAL JOURNAL

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Abstract

Objective: Group-B Streptococci (GBS) are Gram-positive cocci that are the most common cause of early onset neonatal sepsis. The mortality rate of early onset neonatal sepsis has been reported up to 50%. One of the major risks of early onset neonatal sepsis is GBS colonization in birth canal of pregnant women that can infect the baby during process of vaginal delivery. Antibiotic chemoprophylaxis for pregnant women that is colonized by GBS can reduce the risk of early onset neonatal sepsis. The detection of GBS colonization needs Todd Hewitt (TH) enrichment medium to reduce false negative result. Until now, there is no report about either prevalence of colonization or sensitivity pattern of Group B Streptococcus among pregnant women in Denpasar. The aims of this research were to determine the prevalence of GBS colonization and sensitivity pattern of GBS among pregnant women with Todd Hewitt enrichment medium. Method: This research was a descriptive cross-sectional study. Vaginal swab specimens from 35-37 weeks gestation pregnant women were collected and 32 samples that met the inclusion criteria were cultured on Blood agar (BA) plates, Chromagar (CA) plates, and Todd Hewitt (TH) broth. The GBS colonization that grew in culture medium was followed by antibiotic sensitivity test. Results: In the present study, we found that the prevalence of GBS colonization in pregnant women detected with culture method using BA and CA without TH broth was 9.4%, whereas the prevalence with culture method using BA and CA enriched by TH broth was 31.3%. Moreover, GBS showed resistance to penicillin, erythromycin, and cefazolin. It is indicated that TH enrichment medium seems to be promising as a screening method for GBS colonization in pregnant women in Bali. Conclusion: There was an enrichment detection of GBS prevalence colonization in pregnant women detected the swab with culture method using BA and CA enriched by TH compare to BA and CA without TH broth. Moreover, GBS showed resistance to penicillin, erythromycin, and cefazolin. It is indicated that TH enrichment medium seems to be promising as a screening method for GBS colonization in pregnant women in Bali.
Lower Serum Catalase Level is Associated with Preterm Labor among Pregnant Women at Sanglah Hospital Denpasar, Bali-Indonesia Negara, I Ketut Surya; Surya, IGP; Sanjaya, Hariyasa; Anantasika, AAN; Mahardika, I Made
BALI MEDICAL JOURNAL Vol 5 No 3 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Preterm labor is still become a serious health problem in Obstetric and Perinatology with no sensitive biomarker currently approved. Several studies show that decrease antioxidant activity may play significant role in preterm labor. However, only few studies had been conducted to evaluate blood catalase level in preterm labor and assess its role in preterm labor. Objective: The aim this study was to identify the differences of maternal serum catalase level in preterm labor compared with preterm pregnancy. Methods: An observational analytic cross sectional study was conducted from February to December 2014 using pregnant women with 28-36 weeks’ gestational age. Blood catalase level was evaluated by colorimetric method and the data was analyzed by SPPS for Windows 17.0 program. Results: 12 subjects were enrolled and divided into preterm and control group. No significant differences between mean age, gestational age, and parity between preterm and control group. However, blood catalase level was significantly lower in preterm group compared with control group (81.82 ± 20.38 vs 159.38 ± 35.79; p=0.001). Conclusion: Serum maternal catalase level were significantly lower in preterm labor compared with preterm normal pregnancy.
Fetal Sex Determination Using Cell-Free Fetal Dna (cffDNA) in Maternal Blood Sanjaya, I Nyoman Hariyasa; Suwardewa, Tjok Gde Agung; Arijana, I G. Kamasan N.
BALI MEDICAL JOURNAL Vol 5 No 2 (2016)
Publisher : BALI MEDICAL JOURNAL

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Abstract

Background: Prenatal test has routinely performed in antenatal care and has become a part of the obstetric care feature in many countries. Prenatal test is divided into screening and diagnostic test. Recently, the early noninvasive method in order to found and lessen the risk factors of pregnancy loss, has been studied. One of the methods is molecular test using cffDNA which has many screening purpose such as sex determination, aneuploidy, paternal inherited genetic disorder, fetus rhesus, and performed early at 7 weeks of pregnancy. Objective: The purpose of this study is to measure diagnostic value of cffDNA in determining fetal sex prenatally. Methods: In a diagnostic test study, 18 randomized samples were selected and divided based on fetal gender confirmed at birth. The group consisted of 9 pregnant women with male babies and 9 pregnant women with female babies. CffDNA then isolated from maternal blood sample and specific region in Y chromosome termed SRY is detected by PCR and electrophoresis. The data obtained analyzed both descriptively for baseline characteristic and analytically to determine its diagnostic value. Results: This study found significant correlation between SRY detection in cffDNA with male fetal phenotype (p<0.05). The sensitivity of the method is 100% with 89% specificity. In addition, we found 9.09 values for positive likelihood ratio (LR+) and 0 for negative likelihood ratio (LR-). Moreover, the result yielded 100% positive predictive value (PPV+) and 88.8% of negative predictive value (PPV-). Conclusion: This study proofed that cffDNA have a great diagnostic value to determine fetal sex prenatally. However, further study with several group of gestational age mother and better matching is required to further confirm the diagnostic potential of cffDNA.
PERBANDINGAN EFEK OKSITOSIN BOLUS 3 IU, 5 IU, DAN 10 IU TERHADAP KONTRAKSI UTERUS DAN RESPON KARDIOVASKULAR PADA SEKSIO SESAREA DENGAN ANESTESI BLOK SUBARAKNOID Kusuma, Made Adi; Wiryana, Made; Hariyasa Sanjaya, I Nyoman; Gede Widnyana, I Made
Medicina Vol 44 No 3 (2013): September 2013
Publisher : Medicina

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Abstract

Oksitosin merupakan obat yang rutin diberikan setelah kelahiran bayi pada seksio sesarea untukmemulai dan mempertahankan kontraksi uterus adekuat tetapi efek samping kardiovaskulardiketahui muncul setelah pemberian intravena seperti takikardi, hipotensi dan disritmia. Hal iniakibat efek relaksasi otot polos vaskular yang menyebabkan penurunan resistensi vaskular sistemik,hipotensi, dan takikardia. Besarnya efek ini tergantung dosis dan cara pemberiannya. Tujuan penelitianini adalah membandingkan kontraksi uterus, tekanan arteri rerata (TAR), dan laju nadi setelahoksitosin bolus 3, 5, dan 10 IU pada seksio sesarea dengan anestesi blok subaraknoid. Penelitian iniadalah uji klinik acak terkontrol tersamar ganda. Enam puluh enam pasien yang memenuhi kriteriapenelitian dibagi 3 yaitu kelompok 3IU, 5IU, dan 10IU. Oksitosin bolus diberikan setelah kelahiranbayi dalam 30 detik dan dilanjutkan kontinyu 0,04 IU/menit. Kontraksi uterus dinilai oleh operatordan perubahan TAR serta laju nadi dicatat pada lembar penelitian. Tidak ditemukan perbedaanprevalensi kontraksi uterus adekuat antar kelompok penelitian. Penurunan rerata TAR danpeningkatan rerata laju nadi kelompok 3IU secara bermakna lebih kecil dibandingkan kelompok 5dan 10IU, dan kelompok 5IU secara bermakna lebih kecil dibandingkan kelompok 10IU. Simpulanpenelitian ini bahwa oksitosin bolus 3 IU menghasilkan keadekuatan kontraksi uterus yang sama,penurunan TAR dan peningkatan laju nadi lebih kecil dibandingkan oksitosin bolus 5 dan 10 IU padaseksio sesarea dengan anestesi blok subaraknoid.
Feasibility Study on the Implementation of Clinic SIM and ERM integrated Pcare as a BPJS Kesehatan Application at Udayana University Clinic luh sudiarmini; Fajar Manuaba Ida Bagus; Hariyasa Sanjaya I Nyoman
WMJ (Warmadewa Medical Journal) Vol 5 No 2 (2020): November 2020
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.5.2.1636.60-69

Abstract

The development of an information system and communication technology has an impact on the health service sector in the form of electronic-health or e-health. One of the e-health applications is a Clinic SIM and electronic medical records. Not only provides information for the academic communities, but Udayana University Clinic also serves BPJS Kesehatan patients since 2014. After occupying a new building, there have been various obstacles related to the implementation of the management information system. Which it is still being done manually and limited space to store medical record files. One of the efforts to overcome this problem is by implementing a Clinic SIM and ERM. Before the implementation of these activities, a feasibility study was proposed on the application of CSIM and ERM integrated BPJS Healthcare. The purpose of this study was to determine the feasibility of implementing Clinic SIM and ERM which are integrated with Pcare-BPJS at Udayana University Clinic. This study used a qualitative research design. Data collection was started between December 2019 and January 2020 using the in-depth interview method on 9 informants. This study informs that the application of Clinic SIM and ERM integrated BPJS Kesehatan meets the feasibility aspect based on acceptance, demand, integration, and practicality. Conclusion: the obstacles in this study are related to the implementation aspect due to lack of human resources, infrastructure, implementation methods, budget, and minimal application of Clinic SIM and ERM. Keywords: feasibility study, Clinic SIM, ERM, Pcare BPJS Kesehatan
KARAKTERISTIK PASIEN IBU HAMIL DENGAN PREEKLAMPSIA DI RSUP SANGLAH DENPASAR TAHUN 2015 Kadek Budi Juliantari; I Nyoman Hariyasa Sanjaya
E-Jurnal Medika Udayana Vol 6 No 4 (2017): E-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Latar belakang: Preeklampsia dan eklampsia merupakan kondisi spesifik dan komplikasi mayor kehamilan yang biasanya terjadi setelah usia 20 minggu kehamilan. Ibu dengan preeklampsia mempunyai risiko kematian janin perinatal 5 kali lipat lebih besar dibandingkan dengan ibu non-preeclampsia. Di Indonesia, preeklampsia dan eklampsia menjadi salah satu penyebab utama kematian ibu dan kematian perinatal yang tinggi setelah perdarahan. Penelitian ini dilakukan untuk mengetahui karakteristik pasien preeklampsia di RSUP Sanglah Denpasar. Metode: Penelitian ini menggunakan metode deskriptif retrospektif yaitu menggunakan data sekunder berupa rekam medis pasien preeklampsia di Instalasi Rekam Medik RSUP Sanglah Denpasar dari 1 Januari – 31 Desember 2015. Hasil: Dari 108 sampel, didapatkan pasien preeklampsia paling banyak pada usia 20-35 tahun (70,37%), nullipara (49,7%), kehamilan single (98,14%), tanpa riwayat preeklampsia (97,22%), tanpa riwayat diabetes mellitus (99,07%) dan obesitas (62,03%). Simpulan: Terdapat perbedaan hasil antara karakteristik pasien preeklampsia yang disebutkan oleh beberapa literatur dengan karakteristik pasien preeklampsia pada penelitian ini yang dilakukan di RSUP Sanglah Denpasar. Hasil penelitian ini diharapkan dapat dipakai sebagai dasar penelitian lebih lanjut untuk mengetahui karakteristik pasien ibu hamil yang menjadi faktor risiko terjadinya preeklampsia sehingga dapat dilakukan pencegahan dan pengobatan lebih dini.
PERBANDINGAN EFEKTIVITAS TERAPI ORAL DAN INTRAVENA PADA IBU HAMIL DENGAN ANEMIA DEFISIENSI BESI: SEBUAH SYSTEMATIC REVIEW Putu Pandu Eka Setiawan; Ida Bagus Putra Adnyana; I Gede Ngurah Harry Wijaya Surya; I Nyoman Hariyasa Sanjaya
E-Jurnal Medika Udayana Vol 10 No 8 (2021): Vol 10 No 08(2021): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2021.V10.i8.P03

Abstract

ABSTRAK PERBANDINGAN EFEKTIVITAS TERAPI ORAL DAN INTRAVENA PADA IBU HAMIL DENGAN ANEMIA DEFISIENSI BESI Anemia defisiensi besi (IDA) utamanya lebih banyak terjadi pada wanita salah satu faktornya adalah kehamilan. Pilihan pertama dalam pengobatan anemia defisiensi besi untuk hampir semua pasien adalah terapi besi oral. Tujuan dari systematic review ini untuk mengetahui efektifitas terapi intravena dan terapi oral sebagai pengobatan untuk IDA pada Ibu Hamil. Penulisan systematic review ini dilakukan berdasarkan pedoman PRISMA. Pencarian artikel dilakukan pada database Pubmed dan Sciencedirect dari tahun 2016-2020 dengan kriteria inkulsi wanita hamil dengan IDA dan hasil mean Hb untuk setiap intervensi. Judul dan abstrak ditinjau berdasarkan relevansi penelitian. Penilaian kualitas studi menggunakan Cochrane Systematic Review ROB Tools. Pada tahap akhir didapatkan sebanyak enam artikel. Secara umum kualitas studi cukup baik. Berdasarkann Systematic review yang telah dilakukan menunjukan bahwa terapi besi intravena lebih unggul dalam hal tolerabilitas dan koreksi anemia bila dibandingkan dengan terapi oral. Terapi IV juga menghasilkan peningkatan Hb yang lebih cepat. Kata kunci: Kehamilan, Terapi, Anemia Defisiensi Besi
RELATIONSHIP BETWEEN MATERNAL FIRST DAY POSTPARTUM BODY MASS INDEX AND LOW BIRTH WEIGHT NEONATE AT SANGLAH PUBLIC GENERAL HOSPITAL ON SEPTEMBER UNTIL NOVEMBER 2014 Tasa Riszkia; I Nyoman Hariyasa Sanjaya
Bali Journal of Medical and Health Sciences Vol 1 No 1 (2017): volume 1 no 1 Januari 2017
Publisher : Faculty of Medicine, Udayana University

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Abstract

Maternal nutritional status plays crucial role to ensure maternal and fetal well-being. The method that often used to determine someone’s nutritional status is by calculating the Body Mass Index (BMI). In developing countries, researches on the effects of body mass index on maternal and low birth weight neonate are still rare to be found, especially those using first day postpartum Body Mass Index. The aim of our study is to investigate the relationship between maternal first day postpartum body mass index and low birth weight neonate at Sanglah Public General Hospital on September until November 2014. This analytic observational study with cross sectional method used primary and secondary datas which have been taken from patient’s labor medical records in Sanglah Public General Hospital on September until November 2014. The samples are mothers who gave birth and were treated in Bakung Timur, Sanglah Public General Hospital who fulfilled the inclusion and the exclusion criteria. The data were described in the form of frequency tables and tested using a comparative test, Fisher Exact test. From 50 samples, there are 3 samples with low BMI (6%), 16 samples with normal BMI (32%), 12 samples with overweight BMI (24%), 14 samples with obesity I BMI (28%), 5 samples with obesity II BMI (10%). There are 6 neonates with LBW (12%), 42 neonates with NBW (84%), and 2 neonates with HBW (4%). On mothers with obesity II BMI, there are 5 neonates with NBW (100%). On mothers with obesity I BMI, there are 1 neonate with LBW (7.1%), 12 neonates with NBW (85.7%), and 1 neonate with HBW (7.1%). On mothers with overweight BMI, there are 1 neonate with LBW (8.3%), 10 neonates with NBW (83.3%), and 1 neonate with HBW (8.3%). On mothers with normal BMI, there are 2 neonates with LBW (12.5%) and 14 neonates with NBW (87.5%). On mothers with low BMI, there 2 neonates with LBW (66.7%) and 1 neonate with NBW (33.3%). By using Fisher exact test, the p value is less than the predetermined significance level (?= 0.05), it is 0.035. There is correlation between maternal first day postpartum BMI and low birth weight neonate. kaywords:body mass index, low birth weight, first day postpartum
FETAL THERAPYUNTUK KELAINAN BEDAH. JANIN SEBAGAI PASIEN I Nyoman Hariyasa Sanjaya
JURNAL SANGKAREANG MATARAM Vol. 3 No. 2 (2017): Juni 2017
Publisher : SANGKAREANG

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Abstract

Diagnosis prenatal secara dramatis merubah persepsi klinisi terhadap janin. Janin sekarang telah layak disebut sebagai pasien, dan terapi janin terhadap begitu banyaknya jenis kelainan yang terdiagnosis saat prenatal dapat ditawarkan untuk dilakukan. Pengobatan medis bagi janin kini merupakan penanganan standar untuk sejumlah kelainan dan memberikan manfaat terapi yang bermakna. Banyak manfaat didapat untuk berbagai penyakit medis dan terbukti dapat diterapi namun hasilnya masih belum sempurna dan masih diperlukan penelitian serta pengalaman klinis lebih lanjut. Semakin invasif manuver terapi semakin signifikan risikobagi ibu dan janin, serta memunculkan pertanyaan sulit tentang hak-hak yang dimiliki janin, risiko dan manfaatnya. Karena risiko yang tinggi pada pembedahan janin terbuka maka penting sekali untuk melakukan uji klinis terkontrol.
Torsion of ovarian cyst in the third trimester of pregnancy: case report I Nyoman Hariyasa Sanjaya; Cokorda Istri Mirayani Pemayun; Ni Putu Nining Gianni; Made Diah Vendita Sakuntari; Ni Wayan Dewi Purwanti; Ni Luh Made Diah Mas Cahyani Putri; Ni Luh Md Dwi Laxmi Satriani; Ni Komang Anik Pirgantari; Firsta Sesarina Mintariani; Anak Agung Wahyu Putri Agustini; Ketut Widyani Astuti
Indonesian Journal of Perinatology Vol. 3 No. 1 (2022): Available online : 1 June 2022
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v3i1.17

Abstract

Introduction: The entire or partial rotation of the adnexa around its vascular axis or pedicle is known as ovarian torsion. Predisposing factors include short length, unrestricted motion, and a long pedicle. It’s tough to pinpoint the exact cause. Dermoid and serous cyst adenomas are the most common. The complete torsion blocks the venous and lymphatic systems, resulting in stasis, venous congestion, bleeding, and necrosis. The cyst becomes irritable and may explode. A soft cystic mass separate from the uterus can be seen on examination of the affected person, who usually complains of abrupt severe discomfort in the stomach and pelvis. At some time during pregnancy, the risk of ovarian torsion increases by a factor of five. The incidence rate is five per 10,000 pregnancies. Torsion of ovarian tumors was more common among women in their reproductive years. The majority of the instances were seen in pregnant women (22.7%) rather than non-pregnant women (6.1%). Case Description: In this case, we report a 27-year-old primigravida with 36 weeks and 5 days of pregnancy. She presented to the hospital with acute pain abdomen in the lower right (lumbar). She has a history of pregnancy control at a private clinic and there are no abnormalities in her pregnancy. She was hospitalized at 35 weeks 3 days of pregnancy due to the same complaint and has collaborated with the surgeon. No abnormalities were found on the abdominal ultrasound and urology at that time. The baby was born at 36 weeks 6 days of gestation by cesarean section, a twisted ovarian cyst was found on the right ovary, a dextra salpingectomy was performed for oophorectomy and an appendicectomy was also performed at the same time in collaboration with the surgeon. A healthy baby with a weight of 2300 grams and full of breastfeeding. Conclusion: This example demonstrates the problem of manufacturing desirable excellent radiological ultrasound imaging of the pelvic organs in late pregnancy. ultrasound exam in early pregnancy has to also be geared toward the cervix and adnexa which ends up in early analysis and management of ovarian hundreds, thereby fending off future emergency conditions and possible preterm transport.
Co-Authors Adhi Pribadi Aldiansyah, Dudy Aldika Akbar, Muhammad Ilham Aloysius Suryawan Anak Agung Ngurah Anantasika Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Anak Agung Wahyu Putri Agustini Andonotopo, Wiku Bachnas, Muhammad Adrianes Bambang Rahardjo Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun Cokorda Istri Mirayani Pemayun Cut Meurah Yeni Daniel H. Susanto Denni Prasetyo Dyah Pradnyaparmita Duarsa Eka Setiawan, Putu Pandu Endang Sri Widiyanti Evert Solomon Pangkahila Firsta Sesarina Mintariani Firsta Sesarina Mintariani Firsta Sesarina Mintariani Hartanto Hartanto I G A A Novya Dewi I Gede Ngurah Harry Wijaya Surya I Gusti Kamasan Arijana I Ketut Surya Negara I Made Gede Widnyana I Made Mahardika I Nyoman Gede Budiana I Nyoman Wirata I Wayan Murdita Ida Bagus Gde Fajar Manuaba Ida Bagus Putra Adnyana Ida Bagus Putra Adnyana, Ida Bagus IGP Surya, IGP Julian Dewantiningrum Kadek Budi Juliantari Kamajaya, I Gusti Ngurah Agung Trisnu Ketut Widyani Astuti Kurjak, Asim Kusuma, Anak Agung Ngurah Jaya luh sudiarmini Made Adi Kusuma Made Diah Vendita Sakuntari Made Diah Vendita Sakuntari Made Diah Vendita Sakuntari Made Wiryana Marta, Kadek Fajar Murdita, I Wayan Ni Kadek Mulyantari Ni Komang Anik Pirgantari Ni Komang Anik Pirgantari Ni Komang Anik Pirgantari Ni Komang Erny Astiti Ni Luh Made Diah Mas Cahyani Putri Ni Luh Made Diah Mas Cahyani Putri Ni Luh Made Diah Mas Cahyani Putri Ni Luh Md Dwi Laxmi Satriani Ni Luh Md Dwi Laxmi Satriani Ni Luh Md Dwi Laxmi Satriani Ni Luh Putu Yulia Padmawati Ni Nyoman Dewi Purwanti Ni Nyoman Sri Budayanti Ni Putu Nining Gianni Ni Putu Nining Gianni Ni Putu Nining Gianni Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Ni Wayan Dewi Purwanti Nuswil Bernolian Pramono, Mochammad Besari Adi Putra, Wayan Artana Putu Doster Mahayasa Putu Pandu Eka Setiawan Rey Jauwerissa Ryan S. Mulyana Ryan Saktika Mulyana Sri Sulistyowati Stanojevic, Milan Sutandi, Chatrine Syauta, Fetrisya Tasa Riszkia Theresia Monica Rahardjo Tjokorda Gde Agung Suwardewa Utarini, Gusti Ayu Eka Widi, Made Yudha Ganesa Wikantyas Wijaya Surya, I Gede Ngurah Harry Wiradnyana, Anak Agung Gede Putra Wiradnyana, Anak Agung Putra