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Puspita, Sunny
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Pengaruh senam terhadap skala insomnia pada lansia di Panti Jompo Karya Kasih Kota Medan Lubis, Adnan Akbar; Puspita, Sunny; Meldawati, Meldawati
Jurnal Prima Medika Sains Vol. 2 No. 2 (2020): Desember
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v2i2.1256

Abstract

Pada lansia, kualitas tidur pada malam hari mengalami penurunan menjadi sekitar 70-80% sedikit efektif dari usia dewasa. Insomnia adalah ketidakmampuan untuk tidur walaupun ada keinginan untuk melakukannya. Lansia rentan terhadap insomnia karena adanya perubahan pola tidur. Keluhan insomnia mencakup ketidakmampuan untuk tertidur, sering terbangun, ketidakmampuan untuk kembali tidur, dan terbangun pada dini hari. Tujuan penelitian ini adalah untuk mengetahui pengaruh senam terhadap skala insomnia pada lansia di Panti Jompo Karya Kasih Kota Medan. Penelitian ini merupakan penelitian quasi eksperimental. pretest-posttest without control group. Hasil penelitian ini menunjukkan bahwa usia bahwa paling banyak responden berusia 61-70 tahun di Panti Jompo Karya Kasih Medan. Berdasarkan jenis kelamin paling banyak perempuan di Panti Jompo Karya Kasih Medan. Hasil uji analisis dijumpai nilai p 0,001 yang artinya signifikan adanya perbedaan yang signifikan tingka insomnia Sebelum dan Sesudah dilakukan Senam Lansia di Panti Jompo Karya Kasih Medan.
Hypolipidemic and Hypoglycemic Potentials of Garlic Extract in High-Fat Diet and Streptozotocin-Induced Wistar Rats Lie, Veronica; Girsang, Ermi; Chiuman, Linda; Puspita, Sunny
Jurnal Kesehatan Vol 16 No 2 (2025): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v16i2.5003

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels and often associated with hypercholesterolemia. Garlic (Allium sativum Linn.), rich in bioactive compounds such as allicin, saponins, and flavonoids, has been widely reported to possess lipid- and glucose-lowering properties. This study aimed to evaluate the hypolipidemic and hypoglycemic effects of garlic extract in Wistar rats subjected to a high-fat diet and streptozotocin (STZ) induction. A laboratory experimental design with a post-test-only control group was employed. For cholesterol assessment, hypercholesterolemic rats were administered garlic extract at doses of 0.05, 0.10, and 0.20g/head/day, while diabetic rats induced with STZ received doses of 100, 250, and 500 mg/kg body weight per day, with corresponding control groups. Garlic extract significantly reduced mean cholesterol levels in a dose-dependent manner (130.60mg/dL, 121.80mg/dL, and 112.00mg/dL for 0.05, 0.10, and 0.20g/head/day, respectively). In contrast, mean blood glucose levels showed a marginal decrease with increasing doses (282.80 mg/dL, 271.20mg/dL, and 269.27mg/dL at 100, 250, and 500mg/kgBW/day, respectively). However, no statistically significant differences were observed among groups (p=0.706, one-way ANOVA). These findings suggest that garlic extract exhibits a potent cholesterol-lowering effect in hypercholesterolemic rats but has a limited impact on blood glucose reduction under the tested conditions. Further studies are warranted to determine the optimal dosage and underlying mechanisms of action. 
Effect of Garlic Extract on Cholesterol and Glucose in High-Fat Diet STZ Induced Rats Veronica, Veronica; Girsang, Ermi; Chiuman, Linda; Puspita, Sunny
Eduvest - Journal of Universal Studies Vol. 6 No. 1 (2026): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v6i1.52663

Abstract

Diabetes Mellitus (DM) is a chronic metabolic disease characterized by elevated blood glucose levels and is linked to an increased risk of hypercholesterolemia. Garlic (Allium sativum Linn), which contains bioactive compounds such as saponins and flavonoids, has potential for managing these conditions. This study aimed to evaluate the effects of garlic extract on two parameters: blood cholesterol levels in Wistar rats fed a high-fat diet and blood glucose levels in rats induced with streptozotocin (STZ). A laboratory experimental post-test-only control group design was used. For cholesterol assessment, hypercholesterolemic rats were treated with garlic extract at doses of 0.05, 0.10, or 0.20 g/head/day, alongside negative and positive control groups. For glucose assessment, STZ-induced diabetic rats received garlic extract at 100, 250, or 500 mg/kgBW/day, with corresponding control groups. Garlic extract significantly reduced mean cholesterol levels in a dose-dependent manner (130.60 mg/dL, 121.80 mg/dL, and 112.00 mg/dL for 0.05, 0.10, and 0.20 g/head/day, respectively). In contrast, mean blood glucose levels showed a marginal decrease with higher doses (282.80 mg/dL, 271.20 mg/dL, and 269.27 mg/dL for 100, 250, and 500 mg/kgBW/day), but no statistically significant differences were observed among groups (P = 0.706, one-way ANOVA). These findings suggest that garlic extract exhibits a significant cholesterol-lowering effect in hypercholesterolemic rats but does not markedly reduce blood glucose levels in STZ-induced diabetic rats at the tested dosages.
Co-Authors Chiuman, Linda Girsang, Ermi Lie, Veronica Lubis, Adnan Akbar Meldawati Meldawati VERONICA VERONICA