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The Anti-Bacterial Potency of Tamarind (Tamarindus Indica L.) Seed Coat Extract Against the Growth of Staphylococcus aureus ATCC® 29213TM (In Vitro) Nasution, Minasari; Hasibuan, Mirzan; M. Rizki Kurniawan Syahputra
Dentika: Dental Journal Vol. 26 No. 1 (2023): Dentika Dental Journal
Publisher : TALENTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/dentika.v26i1.9411

Abstract

The prevalence of oral bacterial infections, such periodontitis caused by Staphylococcus aureus is a global issue affecting several countries, including Indonesia. However, the use of Tamarind (Tamarindus indica L.), a multifunctional plant with antibacterial, antidiabetic, anticholesterol, antioxidant, and analgesic effects, has proven to be effective overcome this issue. The antimicrobial compounds of tamarind such as polyphenols, tannins, and anthocyanins, which damage cell walls, inactivate enzymes, and interfere with protein transport, involve bacteria lysis. Therefore, this study aims to determine the antibacterial effect of tamarind seed coat extract against Staphylococcus aureus ATCC® 29213TM. The design of this study is experimental laboratory, with a post-test-only control group design, which was analyzed using ANOVA and Least Significant Difference (LSD) tests. The parameters measured included the zone of inhibition, Minimum Inhibitory Concentration (MIC), and Minimum Bactericidal Concentration (MBC) at various extract concentrations of 15%, 10%, 5%, and 2.5%. The inhibition zone was determined using the blank disk method with a digital caliper, while the MIC and MBC were measured using the dilution method. Tamarind seed coat was extracted using a maceration method with 70% ethanol, divided into four group concentrations. The results showed average inhibition zones of 15 mm, 12.7 mm, 10.6 mm, and 0 mm at concentrations of 15%, 10%, 5%, and 2.5%, respectively. The MIC and MBC obtained through the dilution method in the tube were clearer at 5% and turbid at 15%. Furthermore, the value of both parameters at 5% and 10% were determined by subculturing the solution onto Mueller Hinton Agar (MHA) media. Based on the results, higher concentrations of the extract were more effective against Staphylococcus aureus ATCC® 29213TM.
Training On Improving Training On Improving Health Cadres Capacity In Eradication of Tuberculosis Disease In Communities Kusumawati, R Lia; Hasibuan, Mirzan; Lubis, Inke Nadia Diniyanti
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2020): ABDIMAS TALENTA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.553 KB) | DOI: 10.32734/abdimastalenta.v5i2.4315

Abstract

Tuberculosis (TB) is an important issue in public health, where Indonesia ranks second in the world after India and China. The discovery of TB suspects and cases through health facilities is very important, this makes the role of health cadres in the community in the discovery of TB suspects in their area. The purpose of this community service activity is to train health cadres in an effort to increase the capacity of knowledge about tuberculosis (TB). Health cadres in the PKK area of ​​Medan Tuntung District have not been exposed to special training in tuberculosis infectious diseases. The results of the training show that there is a significant difference between the knowledge of tuberculosis infectious disease before training (pre-test) compared to after training (post-test) (p value <0.05). The results of the pre-test scores showed that cadre knowledge before training was categorized as good as 12/30 (40%) and cadre knowledge increased after receiving special training on Tuberculosis which was categorized as good at 26/30 (87%).
Detection of SARS-CoV-2 Post COVID-19 Vaccination in Health Workers in the COVID-19 Isolation Room Kusumawati, R Lia; Hasibuan, Mirzan; Joli, Jelita Siregar
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 8 No. 1 (2023): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/abdimastalenta.v8i1.10273

Abstract

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a type of virus that causes COVID-19 and is a global health problem that has a significant impact on the health of people around the world, including Indonesia. Health workers (nakes) as the frontline have a higher risk of exposure, especially health workers who work in the COVID-19 isolation room in hospitals. Health workers are the main priority for COVID-19 vaccine recipients, but post-vaccine infection does not rule out the possibility of COVID-19 infection due to health workers as health service providers who interact with other health workers or patients, or in patients who are not on transmission-based alert. Detection of SARS-CoV-2 should continue to be investigated and further action to reduce the risk of infection to health workers. This community service activity was carried out to help facilitate health workers during the post-vaccination SARS-CoV-2 examination (I, II and booster III). Of the 73 health workers, nurses are the health workers who mostly work in the COVID-19 isolation room 56 (77%), doctors 11 (15%), midwives 4 (5%) and laboratory assistants 2 (3%). Based on the results of the COVID-19 examination using the RT-PCR method from the nasopharyngeal swab sample, it showed that there were 19 health workers who were infected with COVID-19 before vaccination, namely 1 (1.3%) doctors and 18 (24.6%) nurses. The decrease in infection with health workers decreased after health workers received the first vaccination, where only 1 (1.3%) doctors and 2 (2.7) nurses were reinfected, the increase in the number of health workers infected with SARS-CoV-2 after vaccination II was 3 (4.1%) doctors, 12 (16.4%) and 2 (2.7%) midwives. The results of the detection of SARS-CoV-2 in 73 health workers who had been vaccinated with booster III (moderna) did not find any SARS-CoV-2 infection, indicating that vaccine III increases self-protection against SARS-CoV-2 infection.