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Relationship between Vascular Cell Adhesion Molecule-1 (Vcam-1) Level with Severity Degree of COVID-19 Patients at General Hospital H. Adam Malik Medan Elvira; Siregar, Jelita; Lubis, Inke Nadia Diniyanti; Herman Hariman
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 4 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i4.14410

Abstract

Background: The mechanism and pathogenesis of COVID-19 that distinguishes asymptomatic, mild, moderate, severe to critical symptoms is not yet known with certainty. Endothelial dysfunction and immune thrombosis serve as a profound pathogenic mechanism in COVID-19. Vascular Cell Adhesion Molecule-1 (VCAM-1) is a major regulator of leukocyte adhesion that contributes to the formation of thrombosis. The purpose of the study determine the relationship between VCAM-1 level with the severity degree in COVID-19 patients. Methods: An analytical study with a cross-sectional design was conducted from September – March 2022. This study was followed by 50 patients aged over 18 years with moderate, severe, and critical degrees of COVID-19 admitted to Haji Adam Malik General Hospital Medan by excluding malignancy and pregnancy patients. Serum VCAM-1 levels were measured using Chemwell Analyzer.  Results: Among 50 patients, 33 patients (66%) were male and 17 patients (34%) were female. The mean age was 57 years with the youngest 19 years old and the oldest 81 years old. The median level of VCAM-1 was 23,02 ng/mL (10.96 ng/mL - 50.63 ng/mL). The median concentration of VCAM-1 was 37.85 ng/mL (15,59 – 50.63), 36.68 ng/mL (19.58 – 49.71), and 18.83 ng/mL (10.96 – 46.32) for critical, severe, and moderate degree respectively (p = 0.001). The cut-off value of VCAM-1 levels to predict the severity of COVID-19 is 32.01 ng/mL. Conclusions: There is a significant relationship between VCAM-1 levels and the severity of COVID-19.
Training On Improving Training On Improving Health Cadres Capacity In Eradication of Tuberculosis Disease In Communities Kusumawati, R Lia; Hasibuan, Mirzan; Lubis, Inke Nadia Diniyanti
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2020): ABDIMAS TALENTA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (146.553 KB) | DOI: 10.32734/abdimastalenta.v5i2.4315

Abstract

Tuberculosis (TB) is an important issue in public health, where Indonesia ranks second in the world after India and China. The discovery of TB suspects and cases through health facilities is very important, this makes the role of health cadres in the community in the discovery of TB suspects in their area. The purpose of this community service activity is to train health cadres in an effort to increase the capacity of knowledge about tuberculosis (TB). Health cadres in the PKK area of ​​Medan Tuntung District have not been exposed to special training in tuberculosis infectious diseases. The results of the training show that there is a significant difference between the knowledge of tuberculosis infectious disease before training (pre-test) compared to after training (post-test) (p value <0.05). The results of the pre-test scores showed that cadre knowledge before training was categorized as good as 12/30 (40%) and cadre knowledge increased after receiving special training on Tuberculosis which was categorized as good at 26/30 (87%).
The impact of pig ownership, history of exposure to worms, and personal hygiene on taeniasis infection in Silou Kahean District Sitanggang, Ismail Juli Rico; Darlan, Dewi Masyithah; Ramayani, Oke Rina; Lubis, Inke Nadia Diniyanti; Hutagalung, Sunna Vyatra
TROPHICO Vol. 5 No. 2 (2025): TROPHICO: Tropical Public Health Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/trophico.v5i2.23187

Abstract

Taeniasis remains a zoonotic public health concern in communities with traditional pig farming systems. Silou Kahean District, Simalungun Regency, is an endemic area where free-range pig husbandry increases exposure risk and may sustain persistent local transmission. This study aims to analyze the relationship between pig ownership status, the number of pigs owned, and pig husbandry practices with the incidence of taeniasis in Silou Kahean District, Simalungun Regency. This cross-sectional quantitative study (October 2024–June 2025, Silou Kahean, Simalungun) analyzed 270 cluster-randomized respondents from a population of 21,149 using structured questionnaires and Kato-Katz fecal examination. Associations between pig ownership, pig density, husbandry method, and taeniasis infection were tested using chi-square (95% CI). The findings revealed a significant relationship between pig ownership and the occurrence of taeniasis (p-value = 0.002; PR = 5.513; 95% CI: 1.953–15.560), indicating that respondents who owned pigs had a higher risk of infection than those who did not. The number of pigs owned also showed a significant association with infection (p-value = 0.035). Furthermore, husbandry methods significantly influenced the occurrence of taeniasis (p-value = 0.0001), with a higher prevalence observed among respondents practicing free-range pig rearing compared to those using pen systems. Pig ownership, higher pig density, and free-range husbandry are significant risk factors for taeniasis in Silou Kahean District. Community education, sanitation improvement, and stronger livestock supervision are critical to interrupt transmission in endemic areas.
Prevalence and Risk Factors of Trichuris trichiura Infection among Elementary School Students in Palipi District, Samosir Regency, North Sumatera, Indonesia Sembiring, Elly Susanti Br.; Siahaan, Lambok; Lubis, Inke Nadia Diniyanti; Carolina, Yoan; Adriztina, Indri
Jurnal Epidemiologi Kesehatan Komunitas Vol 11, No 1: Februari 2026
Publisher : Master of Epidemiology, Faculty of Public Health, Diponegoro University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jekk.v11i1.31287

Abstract

Background: Infection with Trichuris trichiura continues to affect populations in tropical and subtropical regions, particularly school-aged children living in environments with inadequate sanitation. This study was conducted to estimate the prevalence of T. trichiura infection and to identify associated risk factors among elementary school students in Palipi District, Samosir Regency, North Sumatra, Indonesia.Methods: This cross-sectional study was conducted from January to March 2025 in five elementary schools in Palipi District, Samosir Regency. A total of 109 students who met the inclusion and exclusion criteria and agreed to participate were recruited through school-based screening. Stool samples were examined using the Kato–Katz method at the Parasitology Laboratory, Universitas Sumatera Utara. Data on handwashing habits, diarrhea history, stunting status, and nail hygiene were collected using structured assessments. Anthropometric measurements and hematological parameters were also recorded. The data analysis involved descriptive statistical methods and chi-square testing, with statistical significance set at p < 0.05.Result: The prevalence of trichuris trichiura infection was 14.7%. Diarrhea was significantly associated with infection (p = 0.010), while stunting, handwashing with soap, and nail hygiene were not significantly associated (p > 0.05). Infected children showed slightly lower mean height, BMI, and hemoglobin levels; however, these differences were not statistically significant..Conclusion : Trichuris trichiura infection remains a public health concern among elementary school students in Palipi District. Diarrhea was significantly associated with infection. Strengthening hygiene promotion and sanitation programs at the school and community levels may help reduce transmission.