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All Journal E-Jurnal Medika Udayana Jurnal Kesehatan Andalas
Driansha, Cindy Liora
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Health Professions Medicine & Pharmacology

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HUBUNGAN DERAJAT DYSMENORRHEA DENGAN KONSISTENSI FECES PADA MAHASISWI KEDOKTERAN UNIVERSITAS UDAYANA Driansha, Cindy Liora; Adiatmika, I Putu Gede; Dinata, I Made Krisna; Purnawati, Susy
E-Jurnal Medika Udayana Vol 11 No 4 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i04.P02

Abstract

Gastrointestinal symptoms such as fecal consistency change commonly found in menstrual women. Women who have dysmenorrhea are likely to experience it than women without dysmenorrhea. This study aims to identify relationship between dysmenorrhea intensity with fecal consistency change among medical students of Udayana University. The hypothesis of this study is there is relationship between dysmenorrhea intensity with fecal consistency change among medical students of Udayana University. This study used analytic cross-sectional design. Questionnaires given to all medical students of Udayana University consists of questions about respondents’ identity, exclusion criteria, dysmenorrhea intensity in last menstruation based on Verbal Multi-dimensional Scoring System, and fecal consistency category based on Bristol Stool Scale. A total of 389 questionnaires collected and selected to rule out ineligible data. Eligible data were analyzed using descriptive test and Fisher Exact Test. Respondents involved in this study were female students aged 18-25 years. A number of 22.6% of respondents did not experience dysmenorrhea, while 59.1% had grade 1 dysmenorrhea, 16.5% grade 2, and 1.7% grade 3. A number of 14.8% of respondents had abnormal hard fecal consistency, 84.3 % normal, and 0.9% abnormal soft. There was no significant relationship between dysmenorrhea intensity and fecal consistency with P value equals to 0.238. This can caused by various factors such as diet, physical activity, sleep quality, stress, and different defecation habits of each respondents. Based on the results, it is concluded that there is no significant relationship between the dysmenorrhea intensity and the fecal consistency among medical students at Udayana University.
Potensi Ekstrak Kunyit (Curcuma longa) Terhadap Kadar Ischemia Modified Albumin (IMA) pada Tikus Model Penyakit Jantung Koroner Dharmaputra, Gde Arisetyawan; Veronica, Elvina; Driansha, Cindy Liora; Satyarsa, Agung Bagus Sista; Dewi, Ni Wayan Sucindra
Jurnal Kesehatan Andalas Vol. 9 No. 3 (2020): Online September 2020
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jka.v9i3.1392

Abstract

Penyakit Jantung Koroner (PJK) adalah penyakit kardiovaskuler akibat penyempitan pembuluh darah koroner yang menyebabkan iskemia miokard, sehingga mengakibatkan apoptosis sel. Kunyit mengandung senyawa yang berperan sebagai anti inflamasi, seperti kurkumin.  Tujuan: Menentukan pengaruh kandungan kurkumin pada kunyit (Curcuma longa) terhadap kadar Ischemia Modified Albumin (IMA). Metode: Desain penelitian ini adalah rancangan post-test only control group dengan menggunakan tikus wistar jantan sebanyak 30 ekor yang terbagi ke dalam 5 kelompok yaitu, kelompok 1 kontrol negatif, kelompok 2 kontrol positif, kelompok perlakuan 1, 2, dan 3. Kelompok perlakuan masing-masing mendapatkan ekstrak kunyit dengan variasi dosis 50, 100, dan 200 mg/kgBB. Pemeriksaan kadar IMA dalam serum darah menggunakan teknik ELISA. Data dianalisis dengan uji One-Way Anova. Hasil: Kadar IMA pada masing masing kelompok adalah kelompok 1 kontrol negative = 300,471 ng/mL, kelompok 2 kontrol positif = 333,357 ng/mL, kelompok perlakukan 1 dosis 50mg/kg = 232,317 ng/mL, kelompok perlakukan 2 dosis 100 mg/kgBB = 173,385 ng/mL, dan kelompok perlakuan 3 dosis 200 mg/kgBB =  217,358 ng/mL. Hasil analisis statistik menunjukkan tidak terdapat perbedaan yang bermakna kadar IMA antara semua kelompok penelitian, yakni kelompok kontrol positif, kontrol negatif, maupun kelompok perlakuan (p>0,05). Berdasarkan Independent  t-test menunjukkan terdapat perbedaan yang bermakna kadar IMA antara kelompok perlakuan ekstrak kunyit 100 mg/kgBB, 200 mg/kgBB dengan kelompok kontrol positif. Simpulan: Ekstrak kunyit berpengaruh terhadap kadar IMA.Kata kunci: IMA, kunyit, kurkumin
Co-Authors Agung Bagus S. Satyarsa Dewi, Ni Wayan Sucindra Dharmaputra, Gde Arisetyawan I Made Krisna Dinata I Putu Gede Adiatmika Susy Purnawati Veronica, Elvina