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Assessment of one-year overall survival among stage III breast cancer patients Darwito; Sari, Ika Puspita; Wijayana, Singgih; Mahardinata, Nur Azid; Anwar, Sumadi Lukman; Ridhayani, Firda
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 2, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss2.art6

Background: The results of a comprehensive diagnosis, combined with the individual's general state, establish the appropriate therapeutic care for breast cancer patients. These management disparities have an impact on clinical outcomes, which may influence patient survival. The evaluation process of breast cancer management is essential as a strategy to boost the therapy's effectiveness in the future year. Objectives: Assessing survival rate, one-year overall survival, among stage III breast cancer patients.Methods: An observational study was conducted comprising a retrospective cross-sectional study. Data collected retrospectively from the medical record followed a total sampling technique. This study included patients with breast cancer as a main diagnosis with or without comorbidities and aged ≥ 18 years when undergoing their first diagnosis. Moreover, the exclusion criteria were patients who had incomplete medical record data, undergoing breast cancer treatment at other healthcare facilities, unspecified clinical stage, and patients who had been diagnosed with non-stage III breast cancer. The survival time of the participants is defined as the number of months from initial diagnosis to their last status (alive, died, or loss of follow-up). One-year overall survival was projected using the Kaplan-Meier curve and presented as a percentage with a 95% confidence interval. Results: Of the 23 patients with stage III breast cancer and the mean age was 57.39 ± 10.417 years. The one-year overall survival for stage III breast cancer was 78.3%. In addition, metastases conditions were associated with worse one-year overall survival compared to patients without metastases (40.0% vs 88.9%, p=0.028).Conclusion: The survival rate of breast cancer patients remains lower than in another recent study from Indonesia. This indicates the requirement of treatment strategies evaluation.

The Effect of the Covid-19 Pandemic on Increased Anxiety of Cancer Survivors of Wijayakusuma Group Prima, Ian Oscar; Darwito
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 4 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i4.488

Background. Corona Virus Disease-19 (COVID-19) is an infectious disease caused by the SARS-CoV2 virus. The increasing number of COVID-19 cases have caused anxiety problems in several countries. Breast cancer patients already have anxiety about their own disease. During the COVID-19 pandemic, this anxiety might be increased due to the fear of getting infected both in the environment where they live or in the hospital. Methods. This is a descriptive observative study, on females with history of cancer in the Wijayakusuma group, Dr. Kariadi Hospital, Semarang, Central Java during February – March 2021. Data collected using questionnaire based on Generalized Anxiety Disorder 7-item (GAD-7) that the question was modified for evaluating anxiety about COVID-19 pandemic in breast cancer patients. Data analyzed using SPSS 23rd version Results. In this study, the breast cancer patient who not anxious were 19.1%, slightly anxious 35.5%, moderate anxious 23.6%, and severe anxious 21.8%. 74,5% patients feel they must wash their hands more often. 60,9% were worried about possibility of contracting COVID-19 of their members, 49,1% afraid of COVID-19, 50,9% were not afraid about COVID-19, 44,5% feel uncomfortable when think about COVID-19, and 40,9% Feel that COVID-19 is life-threatening. Conclusion. There was increase of anxiety level. There was a behavioral change in patients where patients wash their hands more often due to the COVID-19 pandemic.

The Effect of the Covid-19 Pandemic on Increased Anxiety of Cancer Survivors of Wijayakusuma Group Prima, Ian Oscar; Darwito
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 6 No. 4 (2022): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v6i4.488

Background. Corona Virus Disease-19 (COVID-19) is an infectious disease caused by the SARS-CoV2 virus. The increasing number of COVID-19 cases have caused anxiety problems in several countries. Breast cancer patients already have anxiety about their own disease. During the COVID-19 pandemic, this anxiety might be increased due to the fear of getting infected both in the environment where they live or in the hospital. Methods. This is a descriptive observative study, on females with history of cancer in the Wijayakusuma group, Dr. Kariadi Hospital, Semarang, Central Java during February – March 2021. Data collected using questionnaire based on Generalized Anxiety Disorder 7-item (GAD-7) that the question was modified for evaluating anxiety about COVID-19 pandemic in breast cancer patients. Data analyzed using SPSS 23rd version Results. In this study, the breast cancer patient who not anxious were 19.1%, slightly anxious 35.5%, moderate anxious 23.6%, and severe anxious 21.8%. 74,5% patients feel they must wash their hands more often. 60,9% were worried about possibility of contracting COVID-19 of their members, 49,1% afraid of COVID-19, 50,9% were not afraid about COVID-19, 44,5% feel uncomfortable when think about COVID-19, and 40,9% Feel that COVID-19 is life-threatening. Conclusion. There was increase of anxiety level. There was a behavioral change in patients where patients wash their hands more often due to the COVID-19 pandemic.

Papillary thyroid carcinoma post total thyroidectomy: a case report Darwito; Ardha, Doglas Rama Bayu; Sari, Ika Puspita; Ridhayani, Firda
Indonesian Journal of Pharmacology and Therapy Vol 4 No 2 (2023)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.6980

Thyroid malignancies are considered rare but it is the most common type of endocrine malignancy that increase rapidly over the past decades. Specifically, papillary thyroid carcinoma (PTC) in the pyramidal lobe is extremely rare. Herein, we described a case of recurrence case of PTC in the pyramidal lobe post total thyroidectomy with category VI T2N1M1 (Bethesda classification) with right neck lymph nodes metastasis at once and attempt to determine both clinical presentation and therapeutical strategies to overcome this case to diminish the possibility of tumor recurrence and optimize therapeutic outcomes for PTC recurrence. It was reported a 28 yo female with a diagnosis of PTC from the pyramidal lobe post-total thyroidectomy procedure. A definite diagnosis of PTC is important to understand the patient's condition and as a consideration to decide the appropriate procedure to cure it. The management of PTC with total thyroidectomy followed by removing the possible root source of recurrent PTC, such as the pyramidal lobe, is mandatory to minimize the residual thyroid tissue that dan influenced PTC recurrent. Even though almost all PTC has an excellent prognosis, periodic follow-up after surgery, and patients’ adherence to their medication are still required.

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