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All Journal Medula Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi
Ayu Agustira
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Engineering Health Professions Industrial & Manufacturing Engineering Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Transportation Veterinary

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Tanaman Sambung Nyawa (Gynura procumbens) sebagai Antihiperglikemi Ayu Agustira; Iswandi Darwis; Dian Isti angraini
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.265

Abstract

Diabetes mellitus is a disease with impaired carbohydrate metabolism identified by high blood glucose levels (hyperglycemia) and the presence of glucose in urine (glycosuria) that occurs due to abnormal insulin secretion, insulin activity or both. Diabetes mellitus is one of the biggest cause of deaths in Indonesia, which is proven by the Data of Sample Registration Survey in 2014 where diabetes became the third cause of death in Indonesia after stroke and coronary heart disease. If not handled properly, it will affect the decrease in productivity, increase disability, premature death, etc. Sambung Nyawa Plants (Grynura Procumbens) has been widely used as a traditional medicine as antihyperglycemic. Sambung Nyawa Plants contains saponin compounds, flavonoids, and alkaloids, which can reduce blood glucose levels. The mechanism of reducing glucose by Sambung Nyawa Plants is by secreting insulin in β-pancreatic cells and regenerating β-pancreatic cell damage, as an antioxidant that can bind free radicals, there by reducing insulin resistance, and inhibiting alpha amylase and alpha glucosidase which can break carbohydrates into monosaccharides that can be absorbed by the intestine
Hubungan Derajat Preeklampsia terhadap Kadar Ldh di RSUD Abdul Moeloek Provinsi Lampung Periode Januari-Desember 2018 Ayu Agustira; Putu Ristyaning Ayu S; Ety Apriliana
ABDIKAN: Jurnal Pengabdian Masyarakat Bidang Sains dan Teknologi Vol. 1 No. 2 (2022): Mei 2022
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (275.81 KB) | DOI: 10.55123/abdikan.v1i2.277

Abstract

In preeclampsia, there is a proof that endothelial cells and changes in endothelial cell function hold an important role in the pathogenesis of preeclampsia. LDH serum is an important part of the evaluation of tissue damage associated with endothelial damage. Endothelial dysfunction contributes to inappropriate vasoconstriction and platelet aggregation which is an early sign of hypertension. LDH serum was found to be increased in mild and severe preeclampsia women compared to normal pregnant women in the third trimester but LDH serum values were significantly increased in women with severe preeclampsia. This study was aimed to find the relation between LDH levels and the degree of preeclampsia in RSUD Dr. H. Abdul Moeloek Lampung Province. This study used the data that is collected from medical records of patients with mild preeclampsia and severe preeclampsia who were treated in RSUD Dr. H. Abdul Moeloek on January to December, 2018. The sampling method used was Simple Random Sampling. The results showed that the average LDH level in pregnant women who had mild preeclampsia was 518.88 IU / L, whereas in pregnant women who had severe preeclampsia was 695.02 IU / L. The relation of the degree of preeclampsia to LDH levels using Mann-Withney test with the p value obtained was 0.032, which means p <0.05.
Co-Authors Dian Isti Angraini Ety Apriliana Iswandi Darwis Putu Ristyaning Ayu S