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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal Dunia Farmasi Jurnal Kefarmasian Indonesia
Putri, Noni Rahayu
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Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Formulasi dan Uji Kelembaban Sediaan Lip Balm Ekstrak Kulit Buah Naga (Hylocereus costaricensis (F.A.C Weber) Britton & Rose) Putri, Noni Rahayu
Jurnal Dunia Farmasi Vol 8, No 1 (2023): Edisi Desember
Publisher : LPPM Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdf.v8i1.5480

Abstract

Pendahuluan: Lip balm merupakan sediaan kosmetik yang berguna untuk melembabkan dan mengkilatkan bibir. Kulit buah naga merupakan salah satu sumber antioksidan yang dapat melindungi sel kulit dari kerusakan oksidasi dan radikal bebas, sehingga dapat mempertahankan kelembaban bibir. Tujuan: untuk memformulasi sediaan lip balm dengan menggunakan ekstrak etanol kulit buah naga dan melihat stabilitas fisiknya serta menguji efektivitasnya sebagai pelembab bibir. Metode: Kulit buah naga diekstraksi dengan cara maserasi menggunakan pelarut etanol 96% dan dipekatkan dengan rotary evaporator. Lip balm diformulasi dalam 4 formula dengan variasi konsentrasi ekstrak etanol kulit buah naga 0%, 3%, 5%, dan 7%. Pengujian terhadap sediaan lip balm meliputi uji organoleptis, uji homogenitas, uji oles, pengukuran pH, uji iritasi dan uji stabilitas dengan metode freeze and thaw. Pengujian kemampuan sediaan untuk melembabkan menggunakan alat skin analyzer yang diukur setiap minggu selama 2 minggu. Hasil: semua sediaan lip balm homogen, memiliki pH 4,1-5,6 dan stabil selama 4 minggu penyimpanan. Semua sediaan lip balm ekstrak etanol kulit buah naga tidak mengiritasi kulit. Uji kelembaban untuk F0, F1, F2 dan F3 berturut-turut adalah 47,88%; 65,56%; 71,26%; 95,58%. Kesimpulan: Sediaan lip balm ekstrak etanol kulit buah naga stabil secara fisik dan Uji kelembapan menunjukkan bahwa sediaan lip balm dengan konsentrasi 7% dapat memberikan efek melembabkan kulit bibir paling baik dengan persen pemulihan 95,58%.
Formulasi dan Uji Aktivitas Antioksidan Krim Biji dan Ekstrak Etanol Daun Jambu Biji (Psidium guajava L.) sebagai Body Scrub Putri, Noni Rahayu; Agustin, Diana; Nisa, Khairatun
Jurnal Kefarmasian Indonesia VOLUME 12, NOMOR 1, FEBRUARI 2022
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v0i0.4673

Abstract

Ethanol extract of guava leaf (Psidium guajava L.) contains flavonoids and tannins that are potentially as an antioxidant that may inhibit the activity of free radicals.The aim of this study is to formulate a body scrub cream from ethanol extract of guava leaf (Psidium guajava L.) and test their antioxidant activity.This study used three variations of concentration of ethanol extract 70% of guava leaf (Psidium guajava L.) i.e 1,5%, 2% and 2,5%.Body scrub creams are formulated into O/W type of creams by using guava seeds as a scrub.Evaluation of preparations included organoleptic examination, homogeneity, pH, cream type, stability test, particle size distribution, dispersion test and antioxidant activity test using DPPH method. The evaluation results showed that the physical properties of cream preparations provided good results and meet the requirements of cream preparations.The results of the antioxidant activity test found that the values of IC50 for each formula was F0 (without extract) 379,58 µg / mL, F1 (1,5%) 150,78 µg/mL, F2 (2%) 137,26 µg/mL and F3 (2,5%) 125,84 µg/mL.It can be concluded that body scrub creams of ethanol extract 70% of guava leaves (Psidium guajava L.) has the potential to be developed as a cosmetic preparation that can inhibit free radicals.
Formulation of Body Lotion Ethanol Extract of Kepundung Bark (Baccaurea Macrocarpa (Miq.) Mull Arg.) and Antioxidant Activity Test Putri, Noni Rahayu; Sari, Tisa Mandala; Rahma Z, Sri
Media Farmasi: Jurnal Ilmu Farmasi Vol. 22 No. 1: March 2025
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v22i1.25872

Abstract

The bark of kepundung (Baccaurea macrocarpa (Miq.) Mull Arg.) contains secondary metabolite compounds from polyphenols such as flavonoids, phenolic, terpenoids, and alkaloids, which have the potential for natural antioxidants. This research aims to evaluate of ethanol extract from kepundung bark and formulate the body lotion to test its antioxidant activity using the DPPH method. Body lotion formulas were made with variations in the concentration 0.4, 1.0, and 1.6% of ethanol extract of kepundung bark as active ingredients. The evaluation of body lotion included organoleptic, pH, homogeneity, type of body lotion, stability, viscosity, irritation, and antioxidant activity tests. The results of the physical evaluation of the body lotion meet the requirements. Namely, all formulas are homogeneous, according to skin pH, the viscosity of the preparation ranges from 2500 cP, stable, and does not irritate. The value IC50 antioxidant activity of ethanol extract of kepundung bark was 4.04 ppm. The value IC50 antioxidant activity body lotion at F1, F2, and F3 respect 41.91, 36.98, and 33.13 ppm. The result showed the best formula is F3 with a value IC50 33.13 ppm. Based on the study, the ethanol extract of depending bark and the body lotion has very strong antioxidant activity.
Co-Authors Agustin, Diana Khairatun Nisa Rahma Z, Sri Tisa Mandala Sari