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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Promotif: Jurnal Kesehatan Masyarakat JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH
Luke, Kevin
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Health Professions Medicine & Pharmacology Public Health

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Traditional herbal medicine for hyperuricemia: A review of randomized clinical trials Darmanto, Arief Gunawan; Pribadi, Florence; Sucahyo, Yoselyn; Wiraputri, Arini; Mardhika, Della; Tambuang, Christ; Setiawan, Adinda; Habibah, Ummu; Luke, Kevin
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 2 (2023): December 2023
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v14i2.23678

Abstract

In the last decades, traditional herbal medicine for gout has been rapidly advanced. Numerous herbs have been identified for their hypouricidal effect. This review aims to explain the potential and mechanisms of traditional herbal medicine in reducing serum uric acid (sUA). This review included five RCTs and four traditional herbal medicine formulas from a previous systematic review. Articles published in non-English language were excluded for further analysis. Despite limited RCTs design, the formula of Chuanhu; Tufu, and ZinutriK® were beneficial for hyperuricemic individuals. While Yellow-dragon Wonderful-seed mixture showed limited hypouricemic feature. Based on these findings, traditional herbal medicine holds promising potential in treating hyperuricemia and gout. However, further studies are required.
Review of Modifiable Risk Factors for Gout in Asia Dino Tandoyo, Eric; Pribadi, Florence; Mufti Yuana, Hindri; Citra Videla, Ardelia; Nendra Ateja, Kerta; Syahida, Nawira; Wahid, Ridzal; Luke, Kevin
Promotif : Jurnal Kesehatan Masyarakat Vol. 12 No. 2: DECEMBER 2022
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/promotif.v12i2.2575

Abstract

Gout is the most common inflammatory arthritis in the world, including in the Asia region. Gout is a debilitating, yet preventable disease. The general principle of gout prevention is to regulate circulating UA concentration and other related comorbidities. Identifying gout modifiable risk factors is paramount in gout prevention. This review aims to explain modifiable risk factors for gout, especially in the Asia region. Apart from urate-lowering therapy, modifying gout risk factors consisted of a low-purine diet, mild to moderate exercise, adequate sleep, elimination of smoking exposure, and regulation of comorbidities such as hypertension, obesity, metabolic syndrome, and kidney diseases, lowered the risk of hyperuricemia and gout in Asian population.
THE EFFECT OF RAMADAN FASTING TO BLOOD PRESSURE IN HYPERTENSIVE PATIENTS: A META-ANALYSIS Luke, Kevin; Ferona, Nur Avina; Putri, Hana Letitia Anjani Suwardi; Harelina, Tia; Jeffri, Jeffri; Prastyo, Beny; Priandhini, Sekar Afifah; Atika, Atika
Journal of Community Medicine and Public Health Research Vol. 2 No. 2 (2021): Journal of Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (610.817 KB) | DOI: 10.20473/jcmphr.v2i2.26821

Abstract

Ramadan fasting is a type of time-restricted eating and drinking. Previously, a systematic review drew inconclusive effect of Ramadan fasting on blood pressure in hypertensive individuals. Therefore, this meta-analysis aims to evaluate Ramadan fasting effects on blood pressure in hypertensive individuals. This literature search was conducted in PubMed and Google Scholar. All studies assessing the effect of Ramadan fasting on blood pressure in hypertensive patients were included. Statistical analysis was performed in Review Manager 5.4. A total of 7 studies with 260 patients were analyzed. The male proportion and mean age varied from 41% to 88% and 37.5 years to 60 years, accordingly. Four studies measured blood pressure using the ambulatory method. Ramadan fasting significantly reduces systolic blood pressure (SMD=-0.77, 95%CI [-1.18”-0.36], p=0.0002) and diastolic blood pressure (SMD=-0.79, 95%CI [-1.35”-0.24], p=0.005) in hypertensive patients. Both analyses demonstrated high heterogeneity, yet the results persisted after sensitivity analysis. Publication bias was detected. Ramadan fasting reduces blood pressure among hypertensive patients. However, further and larger studies are required to justify this result.
Co-Authors Atika Atika Citra Videla, Ardelia Darmanto, Arief Gunawan Eric Dino Tandoyo Ferona, Nur Avina Florence Pribadi Harelina, Tia Jeffri, Jeffri Mardhika, Della Mufti Yuana, Hindri Nendra Ateja, Kerta Prastyo, Beny Priandhini, Sekar Afifah Putri, Hana Letitia Anjani Suwardi Setiawan, Adinda Sucahyo, Yoselyn Syahida, Nawira Tambuang, Christ Ummu Habibah, Ummu Wahid, Ridzal Wiraputri, Arini