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All Journal Media Kedokteran Hewan
Ajadi, Abdullateef Abiodun
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Medicine & Pharmacology Veterinary

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Comparative Evaluation of Hemato-biochemical and Oxidative Parameters of Racing Horses Atata, Jamila Abdulhamid; Ajadi, Abdullateef Abiodun; Adam, Muhammed; Olatunji, Aishat Omobolanle; Bisalla, Muhammed; Adamu, Sani
Media Kedokteran Hewan Vol. 36 No. 1 (2025): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v36i1.2025.1-12

Abstract

Racing horses are prone to alterations in hemato-biochemical and oxidative stress parameters. The aim of this study was to determine the effect of racing on hemato-biochemical, and oxidative stress parameters of racing horses. Blood samples were collected from 15 control and 15 racing horses at four intervals (before, immediately after, 30 minutes after, and 24 hours after) to assay for hematological, serum biochemical, and oxidative stress markers.  The result revealed significant changes (P < 0.05) in vital parameters such as erythrocyte count, hematocrit index, hemoglobin concentration, leucocyte count, lymphocyte, neutrophil, neutrophil: lymphocyte ratio, total protein, albumin, urea, creatinine, cortisol, lactate, lactate dehydrogenase, creatinine kinase, aspartate aminotransferase, while glucose, cholesterol, triglyceride, gamma-glutamyl transferase, malondialdehyde, glutathione peroxidase, and catalase remained unaltered (P > 0.05). The alteration in hemato-biochemical parameters reported in this study only lasted for about 30 minutes after racing, with all values returning to the baseline range by 24 hours post-race. Interestingly, the comparable activities of antioxidant stress markers reported suggests that the horses have developed adaptive mechanisms that have conferred them with increased resistance to oxidative stress and reduced oxidative damage. This study demonstrates the importance of schematic monitoring of racing horses peri-racing to prevent racing-induced pathophysiological alterations and promote their general wellbeing.
Ameliorative Effects of Borreria Verticillata Aqueous Extract on Adenium obesum Stem Bark Extract-Induced Histopathological Response of The Gill, Intestine, Liver, and Kidney in Clarias gariepinus (Burchell 1822) Juveniles Muyiwa, Benedict Olurotimi; Sambo, Sohnap James; Ajadi, Abdullateef Abiodun; Adekunle, Usman Abdulrauf
Media Kedokteran Hewan Vol. 36 No. 2 (2025): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v36i2.2025.189-202

Abstract

The study was carried out to determine the effect of Borreria verticillata aqueous extract on Adenium obesum stem bark aqueous extract induced histopathological responses in the gill, intestine, liver, and kidney of Clarias gariepinus juveniles. The study consisted of ten (10) groups of fifteen (15) fish each. Groups II - V received 25, 50, 100, and 200 mg/L of the BVAE, respectively. Group VI received 0.838 mg/L of AOAE only (10% of LC50), while groups VII - X received the combinations of the extracts (GII + GVI, GIII + GVI, GIV+GVI, and GV + GVI, respectively). The histopathology observed in Group VI included complete fusion of secondary lamellae and congested blood vessels, hepatic congestion, periportal inflammation, vacuolation, and hyperplasia of bile canaliculi, hypertrophy of the muscular layer and lamina propria and hyperplasia of the goblet cells, congestion of renal blood vessels, tubular degeneration, and swollen glomeruli. The histopathology induced by exposure in GVI in the gills, liver, and kidneys were ameliorated by the administration of Borreria verticillata extract in Clarias gariepinus juveniles in terms of severity which is more in the gill where there is complete club shaped gill in exposed fish compared to the Borreria verticillata extract treated groups.
Invitro Antimicrobial Activities of Mitracarpus scaber Against Some Common Bacteria of Aquatic Origin Ajadi, Abdullateef Abiodun; Emikpe, Benjamin; Akeem, Ahmed
Media Kedokteran Hewan Vol. 32 No. 3 (2021): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v32i3.2021.119-130

Abstract

Some plants have been reported to be of medicinal values and reserve some antimicrobial properties. One of such plants is Mitracarpus scaber and its effect on bacterial growth is evaluated. The study aimed at evaluating the phytochemical analyses and antimicrobial potentials of Mitracarpus scaber against aquatic bacteria including Aeromonas, Bacillus, Vibrio and Staphylococcus Spp. Leaves of Mitracarpus scaber were collected, washed and air dried and phytochemical analysis and antimicrobial investigation of ethanolic and aqueous extracts of the leaves were carried out against a panel of bacteria isolated from diseased catfish from various farms. The phytoconstituents detected include saponins, tannins, flavonoids, tarpenoids, steroids, anthraquinones and alkaloids in both aqueous and ethanolic extracts. Both aqueous and ethanolic extracts of M. scaber showed varying degree of antibacterial activities but ethanolic extract showed a higher activity against the pathogens tested. The ethanolic extract had zones of inhibition similar to that of standard antibiotics (enrofloxacin) across all tested microbes.  The lowest minimum inhibitory concentration of ethanolic extract of M. scaber was against Bacillus sp with 10mg/ml while the highest was 85mg/ml against Staphylococcus species. The results of the assays showed promising evidences that M. scaber is a potential antibacterial agent against aquatic microbes.  However, further studies are recommended to fractionate its constituents and determine the in vitro and in vivo anti-microbial activities and the exact mechanism of action of the constituents.
TRAUMATIC VENTRICULITIS IN AN AFRICAN OSTRICH: A CASE REPORT Adam, Mohammed; Ajadi, Abdullateef Abiodun; Atata, Jamila Abiodun; Akanbi, Olatunde Babatunde
Media Kedokteran Hewan Vol. 33 No. 1 (2022): Media Kedokteran Hewan
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mkh.v33i1.2022.48-52

Abstract

Traumatic ventriculitis or hardware disease is the gizzard perforation by sharp foreign bodies (metallic or sharp object) that leads to ulcerative lesions.The present Case Report was to investigate through post mortem examination the cause of African ostrich death. Necropsy was conducted on a dead male adult African Ostrich presented to the postmortem unit of the Department of Veterinary Pathology, University of Ilorin, Ilorin, Nigeria. The gross lesions showed multifocal ecchymotic and petechial haemorrhages and lacerations on the left shank and thigh as well as the cloaca and vent of the bird. A perforation of the proventriculus with adhesion of a pointed nail-like metallic sharp object of 9.4 cm in length was observed. Histopathological findings revealed obliteration of tubular and vascular congestion which predisposed the animal to metabolic disorder.
Co-Authors Adam, Mohammed Adam, Muhammed Adamu, Sani Adekunle, Usman Abdulrauf Akanbi, Olatunde Babatunde Akeem, Ahmed Atata, Jamila Abdulhamid Atata, Jamila Abiodun Bisalla, Muhammed Emikpe, Benjamin Muyiwa, Benedict Olurotimi Olatunji, Aishat Omobolanle Sambo, Sohnap James