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All Journal Indian Journal of Forensic Medicine & Toxicology
RaadM.Muhiebes
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Public Health

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Synthesis and Characterization of New Oxo-Aztedine ,Imidazoldine and Thiazolidine Rings on Creatinine and Evaluation of their Biological Activity RaadM.Muhiebes; Entesar O. AL-Tamimi
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 4 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i4.16904

Abstract

This work included preparation of new imine from the reaction of creatinine with aldehydes (4-nitrobenzaldehyde, 4- amino benzaldehyde, cinnamaldehyde) and ketone ( acetophenone ) in ethanol and thepresence of few drops glacial CH3COOH to obtain Schiff bases (1a,1b,1c,1d) Schiff bases were treatedwith monochloroacetyl chloride to produced (2a,2b,2c,2d), with glycine to synthesis (3a,3b,3c,3d) andwith 2-mercaptoacetic acid to prepare (4a,4b,4c,4d). The Prepared compounds had beenmeasured by (FTIR,and1HNMR ) spectroscopic techniques. Some of the derivatives were studied activity against antibacterial,antifungal and antioxidant.
Co-Authors Entesar O. AL-Tamimi