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All Journal Indonesian Journal of Pharmaceutical Education
Andy Suryadi, A. Mu’thi
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Biochemistry, Genetics & Molecular Biology Chemistry Materials Science & Nanotechnology Medicine & Pharmacology

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Karakterisasi Senyawa Minyak Atsiri Ekstrak Etil Asetat Bawang Putih (allium sativum l.) Taupik, Muhammad; Andy Suryadi, A. Mu’thi; Hiola, Faramita; Rannu, Jumriani
Indonesian Journal of Pharmaceutical Education Vol 1, No 2 (2021): Mei-Agustus 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i2.11767

Abstract

Garlic (Allium sativum L.) is one of tuber vegetable crops that is widely grown in various countries in the word and is often used as food spices and medicines. The purpose of this study was to characterize the volatile oil compound ethyl acetate extract of garlic (Allium sativum L.) using Uv-Vis and IR spectrophotometric metods. Several methods used in this research included extraction, identification of compounds, fractionation, thin layer chromatography, prepative thin layer chromatography, and characterization of compounds using Uv-Vis spectrophotometry and IR spectrophotometry. A total of 3000 grams od garlic was macerated using 70% ethanol, then evaporated and obtained a thick extract of 421.5 grams. The results of thin layer chromatography used an eluent ratio of Methanol : Ethyl Acetate (4:2) obtained stains with an Rf value of 0,55. The optimizion result of maximum wavelength of garlic isolated (Allium sativum L.) is 232 nm wich indicated  the presence of an electron transition  n→σ*.The results of IR  spectrophotometry had fuctional groups at wave numbers 3231.530 cm-1 (N-H), 1637.48 cm-1 (C=O), 1014.65 cm-1(C-N). 
Interaksi Obat Pada Pasien Diabetes Melitus Tipe 2 Dengan Penyakit Penyerta Di Rumah Sakit Otanaha Kota Gorontalo Rasdianah, Nur; Hiola, Faramita; Andy Suryadi, A. Mu’thi; Gani, Athira Sri Wahyuni
Indonesian Journal of Pharmaceutical Education Vol 1, No 1 (2021): Januari-April 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i1.9953

Abstract

As the numbers of cases continue to soar, diabetes mellitus or DM is one the most common disease in Indonesia. The WHO predicts that in 2030, numbers of diabetics in Indonesia will rise up to 21.3 million people, compared to 8.4 million people in 2000. Regarding the treatment, most of diabetes cases are commonly treated with pharmacological therapy. In this regard, polypharmacy and medications-related problems might occur during the treatment to control blood glucose level that is concurrent with the treatment of other diseases. Drug Interaction is a common medication-related problem. The present study is aimed to investigate the cases of drug interaction in patients with type-2 DM with comorbid diseases during the period of January-December 2019 in Otanaha Hospital, Gorontalo. As based on the inclusion criteria, the study involved 92 patients with type-2 DM and comorbid disease involved combination of metformin-glimepiride (47%), insulin (19%), metformin (14%), and glimepiride (9%). Moreover, based on the observation, minor interaction occurred the most (47%), followed by moderat interaction (31%) and major interaction. To sum up, the cases of drug interaction in patients with type-2 DM and comorbid disease in Otanaha Hospital, Gorontalo are relatively high. It is further concluded that the pharmacist's role is influential to supervise and monitor the patients medication intake.
Co-Authors Gani, Athira Sri Wahyuni Hiola, Faramita Muhammad Taupik Nur Rasdianah Rannu, Jumriani