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Sindrom Serotonin Raisha Rahmani Rizal; Dewi Nur Fiana
Medula Vol 11 No 2 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i2.186

Abstract

Serotonin (SS) syndrome (also referred to as serotonin toxicity) is a potentially life-threatening drug-induced toxidrome associated with increased serotonergic activity in the peripheral (PNS) and central nervous system (CNS). It is characterized by a dose-relevant spectrum of clinical findings associated with levels of free serotonin (5-hydroxytryptamine [5-HT]), or activation of 5-HT receptors (especially the 5-HT1A and 5-HT2A subtypes), which include neuromuscular disorders, autonomic hyperactivity, and altered mental states. Serotonin toxicity begins within a few hours of taking a drug that causes an increase in serotonin. The three classic sets of clinical features are neuromuscular excitation (eg, clonus, hyperreflexia, myoclonus, rigidity), autonomic nervous system excitation (eg, hyperthermia, tachycardia), and altered mental state (eg, agitation, confusion). Although serotonin syndrome rarely causes death, severe cases are medical emergencies that can rapidly lead to multisystem organ failure. Although many drugs have been implicated in serotonin syndrome, life-threatening cases generally occur only when a monoamine oxidase inhibitor is combined with a selective serotonin re-uptake inhibitor. or non-selective. Awareness of Serotonin Syndrome is critical not only in avoiding inadvertently harmful combinations of therapeutic drugs but also in recognizing the clinical picture when it occurs so that treatment can be started immediately. Doctors and nurses should be aware of serotonin syndrome because drugs that can cause it are often used, and intentional overdoses with drugs that can cause serotonin syndrome are seen with increasing frequency. This makes it difficult to detect and doctors can easily mistake serotonin syndrome for antoher diagnose. In this review, the pathophysiology, clinical features, drugs involved and diagnosis of serotonin syndrome are discussed.
Home Based Programs on Promoting Return to Work in The Phase II of Cardiac Rehabilitation After Coronary Artery Bypass Graft Dewi Nur Fiana; Sunaryo B. Sastradimaja; Dian Marta Sari
Indonesian Journal of Physical Medicine & Rehabilitation Vol 5 No 02 (2016): Indonesian Journal Of Physical Medicine and Rehabilitation
Publisher : Indonesian Journal of Physical Medicine & Rehabilitation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (213.487 KB) | DOI: 10.36803/ijpmr.v5i02.209

Abstract

Background.:The purpose of this case report is to present the benefit of additional home based inteventionprogram given in cardiac rehabilitation phase II of a 50 year old male vetenarian post coronary artery bypassgraft surgery.Methods: A functional approach with the aim of maximising the potency of return to work was adopted. Homeprograms given in this patient is an additional prescribing of overground walking exercise alongside withsupervised exercise with treadmill.Results: Due to his role, he should handle 14 farm. His work required him to move arround in 500 meters eachfarm and he made significant progress from MET 3.2 to 6.29 within 6 weeks and able return to work 4 weeksafter surgery.Conclusion:This finding indicate that additional home based programs was an effective program to promotepatient’s return to work faster.Keywords: CABG, exercise, home program, return to work.
Home Based Programs on Promoting Return to Work in The Phase II of Cardiac Rehabilitation After Coronary Artery Bypass Graft Dewi Nur Fiana; Sunaryo B. Sastradimaja; Dian Marta Sari
Indonesian Journal of Physical Medicine & Rehabilitation Vol 5 No 02 (2016): Indonesian Journal Of Physical Medicine and Rehabilitation
Publisher : Indonesian Journal of Physical Medicine & Rehabilitation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (213.487 KB) | DOI: 10.36803/ijpmr.v5i02.209

Abstract

Background.:The purpose of this case report is to present the benefit of additional home based inteventionprogram given in cardiac rehabilitation phase II of a 50 year old male vetenarian post coronary artery bypassgraft surgery.Methods: A functional approach with the aim of maximising the potency of return to work was adopted. Homeprograms given in this patient is an additional prescribing of overground walking exercise alongside withsupervised exercise with treadmill.Results: Due to his role, he should handle 14 farm. His work required him to move arround in 500 meters eachfarm and he made significant progress from MET 3.2 to 6.29 within 6 weeks and able return to work 4 weeksafter surgery.Conclusion:This finding indicate that additional home based programs was an effective program to promotepatient’s return to work faster.Keywords: CABG, exercise, home program, return to work.