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All Journal International Journal of Scientific Multidisciplinary Research (IJSMR) Science Techno Health Journal
Muhamad Seto Sudirman
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Decision Sciences, Operations Research & Management Education Health Professions Law, Crime, Criminology & Criminal Justice Mechanical Engineering Nursing Public Health Social Sciences

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Uji Toksisitas Ekstrak Etanol Daun Rambai (Baccaurea motleyana Mull. Arg.) terhadap Larva Artemia salina Leach Muhamad Seto Sudirman; Syamsul Rizal Sinulingga; Amiruddin
Science Techno Health Journal Vol. 3 No. 1 (2025): Science Techno Health Journal
Publisher : Science Techno Health Journal

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Abstract

Latar Belakang: Daun Rambai (Baccaurea motleyana Mull. Arg.) merupakan salah satu tumbuhan yang digunakan sebagai obat radang mata, keputihan, sakit mata, dan mengobati luka. Daun Baccaurea motleyana Mull. Arg. mengandung senyawa flavonoid, kuinon, tanin, triterpenoid, steroid, dan glikosida. Senyawa flavonoid dan tanin mempunyai aktivitas sitotoksik.Tujuan: Untuk mengetahui toksisitas pada ekstrak etanol daun Baccaurea motleyana Mull. Arg. terhadap larva Artemia salina Leach. menurut metode Brine Shrimp lethality Test (BST).Metode: Penelitian merupakan penelitian eksperimental dengan Post Test Only Control Group Design. Sampel penelitian dibagi menjadi 6 kelompok yaitu kelompok kontrol (tanpa perlakuan), kelompok perlakuan dengan konsentrasi 5 ppm, 50 ppm, 100 ppm, 500 ppm, dan 1000 ppm dengan 3 kali pengulangan. Potensi toksisitas diketahui dengan cara menghitung jumlah kematian larva 24 jam setelah perlakuan. Data yang diperoleh dianalisis menggunakan analisis regresi linear dan analisis probit.Hasil: Hasil penelitian menunjukkan peningkatan konsentrasi ekstrak etanol daun Baccaurea motleyana Mull. Arg. mempengaruhi peningkatan rata-rata kematian larva Artemia salina Leach. dengan nilai R2 sebesar 0.877 (p-value = 0.05). Hasil analisis probit didapatkan nilai LC50 sebesar 86.662 ppm.Simpulan: ekstrak etanol daun Baccaurea motleyana Mull. Arg. mempunyai potensi toksisitas terhadap larva Artemia salina Leach. yang dikategorikan toksik.
The Effect of Gambir Leaves on Cholesterol Levels in Bangka Regency Muhamad Seto Sudirman; Eva Dewi R Purba; Auronita Puspa Pratiwi
International Journal of Scientific Multidisciplinary Research Vol. 1 No. 8 (2023): September 2023
Publisher : PT FORMOSA CENDEKIA GLOBAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55927/ijsmr.v1i8.6242

Abstract

People in the Province of Bangka Belitung Islands are still using medicinal plants inherited from their ancestors, especially in rural areas that are still far from the reach of health facilities organized by the government as a promotional, preventive and curative effort in overcoming health problems. Gambir leaves are a medicinal plant used to lower blood sugar levels which are used by ethnic Malays in the province of Bangka Belitung Islands. As to achieve the goal of the use of traditional medicine for public health, scientific evidence of quality, safety and efficacy is needed. How is the effectiveness of gambier leaves as a traditional medicine to lower blood sugar in ethnic Malays in the Province of Bangka Belitung Islands. Observe the clinical effectiveness (effectiveness) of the use of gambir leaf boiled water as a traditional medicine to lower blood sugar and determine the safety of the liver and kidneys of ethnic Malays in the Province of Bangka Belitung Islands.  Development of a study of traditional medicine formularies used in patients with hyperglycemia disorders and found natural medicinal ingredients to be the most effective and without side effects on the liver and kidneys
Co-Authors Amiruddin Auronita Puspa Pratiwi Eva Dewi R Purba Syamsul Rizal Sinulingga