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All Journal Jurnal Laboratorium Khatulistiwa
Hardianto, Nova
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology

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Perbedaan Proporsi Sputum Bakteri Tahan Asam Positif pada Pasien Diabetes Melitus Terkendali dan Tidak Terkendali Harahap, Elga Citra Lylyanti; Purwanti, Angki; Hardianto, Nova
Jurnal Laboratorium Khatulistiwa Vol 8, No 1 (2024): November 2024
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i1.1590

Abstract

Currently, when the prevalence of diabetes mellitus (DM) is high and predicted to continue to increase, the elimination of tuberculosis (TB) in Indonesia has not been successful. The challenge is greater due to the comorbidity of both diseases and the complexity of the relationship between the two that is not yet well understood. Therefore, studies on DM-TB comorbidity in various populations are still needed. This study aims to determine the difference in the proportion of positive acid-fast bacillus (AFB) sputum between groups of controlled DM patients (HbA1c <6.5%) and uncontrolled (HbA1c ≥6.5%). The design of this study is cross-sectional, using secondary data (medical records) of 126 DM patients at the Persahabatan Hospital, Jakarta, who underwent examinations in January-June 2024. The results showed that the proportion of positive AFB sputum in the uncontrolled DM patient group was 41.3 percent and in the controlled group was 11.1 percent (based on the Chi-Square test, p-value <0.0001). In addition, the uncontrolled DM patient group had a median (youngest-oldest) age of 55 (37-74) years, while the controlled DM group was 50 (32-70) years (based on the Mann-Whitney test, p-value 0.036). This study shows that the uncontrolled DM patient group had a higher proportion of positive BTA sputum and was significantly older than the controlled DM patient group.
Analisis Korelasi HbA1c dengan Mean Platelet Volume dan Platelet Distribution Width pada Pasien Diabetes Melitus Tipe 2 Azzahra, Andi Dinda; Anhar, Citra Amaniah; Hardianto, Nova
Jurnal Laboratorium Khatulistiwa Vol 9, No 1 (2025): November 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v9i1.2169

Abstract

Controlling blood glucose levels is the main key in treating and preventing diabetic vascular complications. However, routine monitoring of glycemic status using standard HbA1c markers is still hampered by limited costs and health facilities. The platelet index is considered to have potential as a predictor of vascular complications in DM patients. This study aims to examine the correlation of HbA1c with mean platelet volume (MPV) and platelet distribution width (PDW) in type 2 DM patients. This cross-sectional study used medical record data. The sample consisted of 60 patients with type 2 diabetes who received treatment at Pasar Rebo Regional General Hospital, Jakarta, in 2024. All patients had HbA1c levels above 6.5%. The proportion of patients with high MPV and PDW was 5% and 11.7%, respectively. Based on bivariate analysis with the Spearman test, there was a significant correlation between HbA1c levels and MPV values (p-value < 0.05; r = 0.561) and PDW values (p-value < 0.05; r = 0.433). A strong positive correlation was observed between HbA1c levels and MPV values and a moderate positive correlation between HbA1c levels and PDW values, indicating that an increase in HbA1c levels tends to be accompanied by an increase in MPV and PDW values.
Co-Authors Angki Purwanti, Angki Anhar, Citra Amaniah Azzahra, Andi Dinda Harahap, Elga Citra Lylyanti