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All Journal Sumatera Medical Journal Folia Medica Indonesiana
Feriyawati, Lita
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

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High BMI leads to increased breast cancer risk in postmenopausal women Tantoso, Tifanny; Sitorus, Mega Sari; Feriyawati, Lita; Wahyuni, Dian Dwi
Sumatera Medical Journal Vol. 4 No. 1 (2021): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v4i1.3735

Abstract

Obesity is a worldwide problem that has been steadily increasing even in developing countries. Obesity has been linked to various types of cancer, one of which is breast cancer. Breast cancer has been classified into various types based on gene and hormone receptor expressions, which offered new insights to therapies and prognoses. We conducted a case-control study using 42 breast cancer patients and 43 healthy women, all of which are older than 55 years of age and have experienced menopause, and for case subjects, additional immunohistochemistry profiles have been provided. Data were collected by interviews and medical records. For data analysis, we used Pearson’s Chi-Square test and Fisher’s Exact test. Results showed that high BMI is significantly associated with breast cancer, and risk is elevated (p < 0.05, OR = 1.263, 95% CI = 1.007-1.583). No significant association with molecular subtypes was observed.
Ferning and Schirmer Test 1 for the Detection of Grading Severity of Dry Eye Syndrome in Post Phacoemulsification Patients Zubaidah, Tengku Siti Harilza; Lubis, Rodiah Rahmawaty; Feriyawati, Lita
Folia Medica Indonesiana Vol. 58, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Highlights: 1. Females were the most gender who suffer from dry eye syndrome than males. 2. Undergone phacoemulsification patients had frequent dry eye syndrome. 3. Post-phacoemulsification patients were not statistically significant between the Ferning and the Schirmer test. Abstract: Dry eye syndrome is a multifactorial disease on the surface of the eyeball characterized by loss of tear film homeostasis, which is associated with eye symptoms, where there is tear instability and hyperosmolarity, inflammation, and damage to the surface of the eye, as well as neurosensory disorders that act as the cause of this syndrome. The aim of this study was to identify relationship between the Ferning pattern and the Schirmer test 1 in post-phacoemulsification patients. The design of this study was an analytical observational study with a cross-sectional data collection method where the Ferning and Schirmer test 1 were examined to determine the severity of dry eye syndrome in post-phacoemulsification patients. The Ferning test was assessed according to Rolando's classification. In this study, it was found that the gender who suffer from dry eye syndrome are women. The most considerable age is age ≥ 60 years (56,7%). The results showed that the majority of patients experienced dry eyes measured with the Ferning test, and these results were following the previous Schirmer Test 1 examination. The Ferning and Schirmer tests were found to be abnormal in most of the subjects. It was found that there was a significant relationship between the Ferning pattern and the Schirmer test with the calculation of the t-value of 7.345 with a p-value of 0.001. There was a statistically significant difference between the results of Ferning and the Schirmer test in post-phacoemulsification patients.
Co-Authors Harahap, Feby Yanti Lubis, Heny Syahrini Lubis, Rodiah Rahmawaty Sitorus, Mega Sari Tantoso, Tifanny Tuelah, Giselle Iona Rachel Wahyuni, Dian Dwi Zubaidah, Tengku Siti Harilza