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All Journal Indonesian Journal of Midwifery Today Folia Medica Indonesiana
Sitaresmi, Sandra Dewi
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Nursing Public Health

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Pengaruh Umur Terhadap Keaktifan Lansia Pada Posyandu Lansia Sitaresmi, Sandra Dewi; Safriana, Rizka Esty
IJMT : Indonesian Journal of Midwifery Today Vol. 2 No. 1 (2022): IJMT
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/ijmt.v2i1.4828

Abstract

ABSTRACT Elderly is a condition characterized by a person's failure to maintain a balance against physiological stress conditions. Often the elderly and those around them cannot accept the changes and setbacks that occur so that it will cause problems for the elderly such as neglect. The purpose of this study was to determine the effect of age on the activity of the elderly at Integrated Healthcare Centerfor the elderly in Waung Village, Boyolangu District, Tulungagung Regency. This study uses an analytic study, the type of observational research with a case control design. The sample of this study was the elderly of Waung village, Boyolangu district, Tulungagung district in 2022 as many as 23 people. The research sample was taken using a non-probability sampling technique with total sampling type. The data obtained were then analyzed using the chi square test and the results obtained that the value of p = 0.078 means that it is not significant because it is more than 0.05. The conclusion of the research shows that there is no influence of the age of the elderly on the activity of participating in the Integrated Healthcare Center for the elderly in Waung Village.
Effects of lycopene on spermatozoa morphology in balb/c mice exposed to 2-methoxyethanol (2-me) Sitaresmi, Sandra Dewi; I'tishom, Reny; Mustika, Arifa
Folia Medica Indonesiana Vol. 53, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

The compound of 2-methoxyethanol (2-ME) is one of toxic materials that potentially damage male reproductive organs. This compound can enter the body by various means of direct contact through the skin, respiratory and digestive tract. This compound can cause oxidative stress in spermatozoa which is the main cause of spermatozoa dysfunction. Lycopene, also known as red pigment, is an antioxidant class of carotene. Lycopene has antioxidant activity twice stronger than beta carotene and ten times stronger than vitamin E. Thus, the lycopene reaction as an antioxidant in the body is better than vitamin A, C, E, and other minerals. This study was conducted to determine the effects of lycopene on spermatozoa morphology in mice exposed to 2-ME. The study was conducted on 30 mice, divided into 5 groups. The K-group was the control group without 2-methoxyethanol and lycopene, the K + group was the group with 200 mg/kg BW 2-methoxyethanol on days 1-5, and the P1, P2 and P3 groups were the ones with 200 mg/kg BW 2-methoxyethanol on days 1-5 and lycopene doses of 5, 10 and 20 mg/kg BW on days 6-35. 2-ME was given intraperito-neally and lycopene was given per sonde. On day 36, the mice were sacrificed and the epididymis and vas deferens were removed for morphological examination of spermatozoa. The observations were performed using a microscope with 1000x magnification. The results showed that there was significant difference. In the morphology of spermatozoa, the administration of lycopene increases normal morphological percentage of spermatozoa in mice exposed to 2-ME.
Co-Authors Arifa Mustika I'tishom, Reny Rizka Esty Safriana