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Maghfirah, Andi Itha
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Analysis of procalcitonin and urine nitrite to predictor sepsis patients Maghfirah, Andi Itha; Muhiddin, Rachmawati; Handayani, Irda; Kadir, Nursin Abdul
MEDISAINS Vol 19, No 2 (2021)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v19i2.11075

Abstract

Background: Sepsis is a significant health problem worldwide. Various sepsis biomarkers have been studied before, but few data link PCT and urinary nitrite levels to culture result in septic patients.Purposes: This study compares PCT, Urine Nitrite on culture results against their sensitivity to determine variables that can be used to predict sepsis patients.Methods: This is a cross-sectional study by taking data on patients with sepsis aged ≥18 years in 207. Diagnostic tests were performed to determine sensitivity and specificity of PCT, Urine Nitrite, and Blood Culture of septic patients. A Chi-square test was carried out to see the relationship between two parameters and the outcome of sepsis.Results: PCT sensitivity was higher than Urine Nitrite: 74.5%. Specificity of Urine Nitrite was higher than PCT: 88.2%. Procalcitonin has a significant relationship with sepsis patient outcomes (p<0.005).Conclusion: PCT can predict septic patients because it has a higher sensitivity than urine nitrite