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All Journal INDONESIAN JOURNAL OF PHARMACY
Mariani, Ria
Pharmacy, Faculty of Maths and Science (FMIPA), Universitas Garut, Garut, Indonesia
Medicine & Pharmacology

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Anti-inflammatory activity of dominant compound of mahkota dewa fruit Phaleria macrocarpa Scheff. Boerl Mariani, Ria; Wirasutisna, Komar Ruslan; Nawawi, As’ari; Adnyana, I Ketut
Indonesian Journal of Pharmacy Vol 21 No 2, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.241 KB) | DOI: 10.14499/indonesianjpharm0iss0pp129-133

Abstract

The anti-inflammatory effectof dominant compound of mahkota dewa fruit (Phaleria macrocarpaScheff. Boerl), a hydroxyl benzophenon glucoside,to Wistar  female  rats  (using  λ-karagenan  as  inflammatory  inducer)  has  been investigated.   The inflammation was measured by pletismometer.  The test has been used physiology NaCl solution as a control andNaproxen at a dose of 22.5 mg/kg body weight as a standard. Anti-inflammatorytest was showed that the decreased  inflammation  of  the  isolate  at  a  dose  of  22.5  mg/kg  body  has  twice lower than the standard.Key words:  Phaleria  macrocarpa,  anti-inflammatory  activity,  hydroxyl  benzophenon glucoside
Co-Authors I Ketut Adnyana Nawawi, As’ari Wirasutisna, Komar Ruslan