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All Journal International Journal of Integrated Health Sciences Majalah Kedokteran Bandung
Ikhsani, Rizkania
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Health Professions Medicine & Pharmacology

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Smoking Parameters in Coronary Heart Disease Patients Treated at Dr. Hasan Sadikin General Hospital Bandung, Indonesia Prabhaswara, Agastya; Ikhsani, Rizkania; Bijaksana, Transiska Liesmadona; Wahjoepramono, Nicolaus Novian Dwiya; Tarsidin, Najmi Fauzan; Tiksnadi, Badai Bhatara
Majalah Kedokteran Bandung Vol 56, No 2 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3367

Abstract

The association between smoking and coronary heart disease (CHD) has been studied extensively, though smoking parameters that contribute to the development of CHD may still need to be studied further. This cross-sectional study aimed to describe the characteristics of smoking parameters, including the number of cigarettes smoked, age when started smoking, duration of smoking, and cessation of smoking, in CHD patients treated at Dr. Hasan Sadikin General Hospital, Indonesia. CHD patients aged ≥18 years were included from the cardiology outpatient clinic and hospital wards. Smokers (current smokers/quit smoking <6 months) and ex-smokers (quit smoking ≥6 months) were considered patients who had a history of smoking. The Brinkman index, i.e., duration of smoking x number of cigarettes/day, was used to measure the degree of smoking that were categorized into mild, moderate, and severe smokers. Eighty-seven subjects diagnosed with CHD were recruited in this study. Seventy-seven percent of the subjects were male, and the mean age of subjects studied was 58.5±10.4 years. Among all subjects, a history of smoking was found in 66.7% (37.9% smokers and 28.7% ex-smokers), with all composed of male subjects. The age of subjects who had a history of smoking was 20 (15-35) years. Most were moderate smokers (74.1%) from Brinkman Index measurement. Smoking history has a significant association with male sex, lower total cholesterol, and lower LDL levels (p-value <0.05).
Predictors of In-Hospital Mortality in Patients with Infective Endocarditis: A Single-Center Study Hanim, Haifany Fauziyah; Ikhsani, Rizkania; Yudharaputri, Digita Natarina; Cool, Charlotte Johanna; Hasan, Melawati
International Journal of Integrated Health Sciences Vol 13, No 1 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v13n1.3753

Abstract

Background: Infective endocarditis remains a life-threatening condition with high in-hospital mortality, necessitating identification of predictive clinical factors.Objective: To identify predictors of in-hospital mortality in infective endocarditis (IE) patients.Methods: This single-center retrospective study included 88 patients with IE aged ≥ 18 years treated at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia, between September 2019 and May 2023. During hospitalization, data regarding clinical characteristics, blood cultures, and clinical outcomes were assessed to identify the predictors of in-hospital mortality. Data were analyzed using chi-square and binary logistic regression.Results: Among 88 patients with IE, the majority were male (56.8%) and aged < 60 years old (78%). More than two-thirds of patients had valvular heart disease. During treatment, 22 patients (25%) underwent cardiac surgery, and the total in-hospital mortality rate was 35.2%. Although not statistically significant, in-hospital mortality rate was lower in operated patients (22.7% vs 39.4%). In multivariate analysis, septic shock was the only significant predictor of in-hospital mortality (OR 40, 95% CI: 4.7–339, p 0.001)Conclusion: Septic shock is a strong predictor of in-hospital mortality among patients with infective endocarditis. Invasive management by cardiac surgery does not significantly decrease the mortality risk.
Co-Authors Badai Bhatara Tiksnadi Bijaksana, Transiska Liesmadona Cool, Charlotte Johanna Hanim, Haifany Fauziyah Hasan, Melawati Prabhaswara, Agastya Tarsidin, Najmi Fauzan Wahjoepramono, Nicolaus Novian Dwiya Yudharaputri, Digita Natarina