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All Journal International Journal of Social Service and Research
Hiyana TD, Christin
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Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Social Sciences

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Utilization of 7% Piper Betle Linn Nanospray Extract on Second-Degree Perineal Wounds in Postpartum Mothers (A Study of Inflammatory Process (Il-6) and Healing Process Based on the Reeda Scale) Fitriyaningsih, Erna Indah; Kumorowulan, Suryati; Suwondo, Ari; Rahayu, Sri; Hiyana TD, Christin
International Journal of Social Service and Research Vol. 5 No. 6 (2025): International Journal of Social Service and Research
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v5i6.1271

Abstract

Postpartum second-degree perineal lesions are common and trigger an inflammatory response with an increase in IL-6. Suboptimal treatment risks prolonging the inflammatory process and inhibiting wound healing. Piper betle Linn is recognized as an herbal ingredient with anti-inflammatory potential; its nanospray formulation is believed to penetrate deeper layers of the skin, thereby accelerating wound healing. This study evaluated the effectiveness of a 7% betel leaf extract nanospray on the healing of perineal wounds in postpartum care. The study employed a true experimental design with a pretest-posttest control group, involving 40 respondents selected through stratified random sampling. The variables examined were the use of 7% betel leaf extract nanospray and the healing of grade II perineal wounds. Data analysis was conducted using the Kruskal-Wallis test and the independent t-test, followed by the Wilcoxon test. The findings demonstrated that administration of Piper betle Linn 7% nanospray extract significantly accelerated perineal wound healing, as measured by the REEDA scale (p < 0.05), with the majority of the intervention group (65%) exhibiting good healing. However, there was no significant difference in IL-6 levels between the intervention and control groups (p > 0.05). Piper betle Linn 7% nanospray extract is effective in accelerating the healing of grade II perineal wounds in postpartum mothers, as indicated by a decrease in REEDA scores, but does not significantly affect the reduction of IL-6 levels.
Co-Authors Ari Suwondo Fitriyaningsih, Erna Indah SRI RAHAYU Suryati Kumorowulan