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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Cermin Dunia Kedokteran
Hartanto, Felix
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Health Professions Immunology & microbiology Public Health

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Concordance Test Between Dermoscopic and Histopathological Parameteres in Basal Cell Carcinoma Hartanto, Felix; Kusumaputra, Bagus Haryo; Sari, Maylita; Citrashanty, Irmadita; Mappamasing, Hasnikmah; Astari, Linda; Sandhika, Willy; Hidayati, Afif Nurul; Prakoeswa, Cita Rosita Sigit; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.6-11

Abstract

Background: Basal cell carcinoma (BCC) is the most common skin cancer and can cause local tissue damage. BCC can occur in all populations, regardless of skin color. Dermoscopy has compatibility with histopathology in determining the benign or malignant nature of a lesion. Dermoscopy can improve the diagnostic accuracy of BCC by >90%, with 7 parameters that can be found: arborizing vessels, blue-gray ovoid nests, blue-gray dots/globules, maple leaf-like areas, spoke-wheel areas, ulceration, and hiny white areas. Purpose: To assess the compatibility of each dermoscopy parameter with its corresponding histopathological parameters. Methods: Observational analytic study with a cross-sectional approach was performed. Dermoscopy parameters were obtained by reassessing all photographs, while histopathological parameters were obtained from pre-existing slide reviews. Cohen's Kappa test was performed to analyze both variables. Result: A Total of 26 samples met the inclusion criteria. Most BCCs were found in female sex (65.4%), age >50 years (80.8%), and facial location (88.5%). Cohen's Kappa test was significant in 2 out of 7 dermoscopy parameters: "blue-gray ovoid nests" (p = 0.0019; r = 0.458) and "spoke wheel areas" (p = 0.037; r = 0.371). The "shiny white areas” parameter could not be analyzed because there was no negative variation in the examination. The possibility of false positives and negatives could not be ruled out.  Conclusion: Significance between the two variables is found in 28.6% of the 7 parameters analyzed...
Pengerasan Telinga Ganda Kronis: Laporan Kasus Dermatitis Kontak Iritan yang Menyerupai Lepra : Laporan Kasus Alika, Maria Ulfa Noor; Hartanto, Felix
Cermin Dunia Kedokteran Vol 52 No 11 (2025): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1642

Abstract

Introduction: Irritant contact dermatitis (ICD) is an inflammatory cutaneous disorder induced by the breakdown of the barrier and activation of innate immune responses. In the chronic stage, plaques thicken and cause scaling, hyperkeratosis, fissures, rhagades,and/or lichenification. Case: A 34-year-old male presented with both earlobe thickening and minor numbness, particularly whilesweating or being exposed to direct sunlight. Physical examination revealed erythematous patches, as well as edema and thickness of both earlobes. Patch test and slit skin smears yielded negative findings, ruling out allergic contact dermatitis (ACD) and leprosy. The diagnosis of irritant contact dermatitis was caused by sweat and sun exposure. The treatment consisted of twice daily ofdesoximethasone and mupirocin cream, and 10 mg loratadine once daily. Discussion: ICD is an inflammatory cutaneous disorder induced by the breakdown of the skin barrier and the activation of the innate immune response. Thickening and numbness of both earlobes are caused by repetitive irritation from sweat and sunlight exposure over time. Conclusion: Irritant contact dermatitis in both earlobes should be differentiated from other skin diseases, particularly leprosy.
Co-Authors Afif Nurul Hidayati, Afif Nurul Alika, Maria Ulfa Noor Bagus Haryo Kusumaputra, Bagus Haryo Cita Rosita Sigit Prakoeswa Irmadita Citrashanty, Irmadita Linda Astari, Linda M. Yulianto Listiawan Mappamasing, Hasnikmah Maylita Sari, Maylita Willy Sandhika