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The comparison of the Sensitivity Value of Gold Nanoparticles (AuNPs) between ANTAM and Commercial Gold Sources in the Detection of SARS-CoV-2: A Preliminary Study Istianah, Istianah; Vidiawati, Agustina; Alfiyan, Akhmad Irfan; Andreani, Agustina Sus
Molekul Vol 19 No 3 (2024)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2024.19.3.11037

Abstract

Gold nanoparticles (AuNPs) have been developed as a colorimetric sensor to detect SARS-CoV-2 with surface modification using N-ethyl-N′-(3-(dimethylamino)propyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS) and angiotensin-converting enzyme II (ACE-2). The gold sources used in the synthesis are produced by PT Aneka Tambang Indonesia (ANTAM) and commercial gold nanoparticles (AuNPs). This study compares the sensitivity values of ANTAM gold sources and commercial AuNPs in detecting SARS-CoV-2. The AuNPs-ANTAM detection test against the SARS-CoV-2 resulted in LoD and LoQ values of 5.38 ng/mL and 17.92 ng/mL, in the linearity curve range of 10 – 50 ng/mL, respectively. LoD and LoQ values of commercial AuNPs for detecting SARS-CoV-2, respectively, are 6.69 ng/mL and 22.31 ng/mL in the linearity curve range of 10 – 50 ng/mL. Based on the LoD and LoQ values, AuNPs-ANTAM is more sensitive than commercial AuNPs in detecting SARS-CoV-2 over the same range of linearity curves. Keywords: ACE-2, colorimetry sensor, EDC/NHS, gold nanoparticles, SARS-CoV-2, surface Modifications
The Impact of Waste Marble Powder as A Partial Alternative Material for Cement Andreani, Agustina Sus; Taopan , Henda V. R.; Banunaek , Frengky Seki; Nurkhaliza , Farrah
Jurnal Sains Materi Indonesia Vol. 26 No. 1 (2024): Jurnal Sains dan Materi Indonesia
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jsmi.2024.4569

Abstract

Waste marble powder generated from the sawing and the mining activity of marble stone caused environmental problems that harmed human health. This current research aimed to investigate the influence of waste marble powder to substitute cement partially in mortar production. The mortar preparation with the mixture compositions of 0-50% marble powder was investigated for their resistance of compression and their porosity. The characterization was assessed with X-ray Fluorescence (XRF), Scanning Electron Microscopy-Energy Dispersive X-ray (SEM-EDX), Fourier Transform Infra-Red (FTIR), and X-ray Diffraction (XRD). The finding of this research revealed that a replacement by up to 10% marble powder obtained an increase in compressive strength after 28 days. A low level of marble powder to replace cement led to a less porous microstructure of the mortars. These confirmed that waste marble powder could be applied to manufacture mortars. In addition, the utilization of waste marble powder as an alternative building material would reduce the damage to the environment.