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All Journal e-GIGI Jurnal MIPA PHARMACON CHEMISTRY PROGRESS Chemistry Indonesian Journal of Chemical Research
Jemmy Abidjulu
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Engineering Environmental Science Mathematics Medicine & Pharmacology Physics

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Journal : PHARMACON

 1 
AKTIVITAS ANTIOKSIDAN DARI EKSTRAK KULIT NANAS (ANANAS COMOSUS (L) MERR) Hatam, Sri Febriani; Suryanto, Edi; Abidjulu, Jemmy
PHARMACON Vol 2, No 1 (2013): pharmacon
Publisher : PHARMACON

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Abstract

ABSTRACT The objectives of this research were to determine antioxidant n activity from pineapple peal extract. Pineapple peel extracted by maceration, soxhlet and reflux using ethanol 80% as a solvent. Phenolics and flavonoids content of Crude extract were analyzed.Evaluation of antioxidant activity using DPPH free radicals method, The results shows that maceration, soxhlet and reflux extract possess phenolics content 16,53; 28,78; 16,02 g/mL respectively, and  flavonoid total content 3,514; 5,115; 4,414 g/mL respectively. Maceration extract with concentration 3000 g/mL possess low free radical scavenging activity, and soxhlet extract possess the highest.Inhibition concentration 50% (IC50) of soxhlet extract were 602,56 g/mL, it?s indicate that soxhlet extract possess high scavenging of 50% free radicals. This result shows that pineapple peel extract possess phytochemical phenolics and flavonoids that potential to be antioxidant and as active compound of sun screen. Keywords: antioxidant, pineapple peel extract.
PENGARUH SUHU TERHADAP STABILITAS SERTA PENETAPAN KADAR TABLET FUROSEMIDA MENGGUNAKAN SPEKTROFOTOMETER UV-VIS Waney, Rekanita; citraningtyas, Gayatri; Abidjulu, Jemmy
PHARMACON Vol 1, No 2 (2012)
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.1.2012.504

Abstract

Stability is the ability of product to maintain its nature and characteristics similar to itsorigin during storage and use period. Furosemide is one of drugs product that works as diuretic.The aim of this research was to study the effect of temperature on furosemide stability. Themethod using in this research is factorial Complete Random design. There are two factors in thisresearch,factor A is temperature (40oC, 50 oC, and 60 oC) and factor B are period (60, 120 and180 minutes). There are three samples in this research. Analysis of furosemide content usingSpectrophotometer UV-Vis at λ = 271 nm. Obtained data were analyzed using spss ver. 20. Thedifferences between variable were statistical analyzed. The result shows that the decreasing offurosemide in tablet starts at temperature 50°Cafter60minutes heating for sample A and C.Sample B decrease at temperature 50°C after 120 minutes heating.Keywords: stability, furosemide, spectrophotometry UV-Vis
Co-Authors Audy Denny Wuntu Dinar A. Wicaksono Edi Suryanto Erling Pasaraeng Erpi Bangol Gayatri Citraningtyas Ghazaly R. Umaternate Harry S. J. Koleangan Harry S. Koleangan Hendra Mukuan Herling D. Tangkuman Jhon Smith Wongkar, Jhon Smith Koleangan, Harry Krista V. Siagian Lidya I. Momuat Mariska M. Pitoi Martin Aprilino Tambunan, Martin Aprilino Maureen Kumaunang Max R. J. Runtuwene Melin T. Kitong Mercy Ngajow Olivianti, Asriani Pricillia T. Kaawoan, Pricillia T. Rekanita Waney Simatupang, Olivia C. Sitti N. Sultan, Sitti N. Sri Febriani Hatam Stero H. Roring Theo Mukuan Triyono Mojo, Triyono Tumbel, Elsa D. Vanda S Kamu Vanda S. Kamu