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All Journal Journal of Pharmaceutical and Sciences. Jurnal manajemen informasi kesehatan
Rahmadini, Mutia
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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The Relationship Between Physical Activity and Diet and the Incidence of Diabetes Mellitus in the Elderly in Kampung Baru Village Rahmadini, Mutia; Aziza, Nurul; Noviani
Jurnal Manajemen Informasi Kesehatan (Health Information Management) Vol. 10 No. 1 (2025): Health Information and Management
Publisher : Sekolah Tinggi Ilmu Kesehatan Sapta Bakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51851/jmis.v10i1.575

Abstract

Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia and glucose intolerance caused by the pancreas' inability to produce insulin accurately or the body's inability to effectively use the insulin it produces. According to the International Diabetes Federation (IDF), the global incidence of diabetes reached 424.9 million in 2017, and this number is predicted to reach 628.6 million by 2045. This study aims to determine the relationship between physical activity and diet and the incidence of diabetes in the elderly. This study used a quantitative approach with a cross-sectional design. The sample was determined using purposive sampling, resulting in 57 samples. The data collection tool used was a questionnaire, which was then analyzed using the chi-square test. The statistical test results showed a significant relationship between physical activity and the incidence of diabetes in the elderly in Kampung Baru Village with a p-value of 0.009 (p-value <0.05). And there is a significant relationship between diet and the incidence of diabetes in the elderly in Kampung Baru village with a p-value = 0.011 (p-value = 0.05).
Eksplorasi Aktivitas Antimikroba Bakteri Endofit Daun Betadine (Jatropha multifida L.) terhadap Patogen Staphylococcus aureus Arfiandi, Arfiandi; Fadjria , Neri; Nofita, Dewi; Rahmadini, Mutia
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.899

Abstract

Background: Antibiotic resistance has spurred the exploration of novel antibacterial agents, including endophytic bacteria from medicinal plants like Jatropha multifida L. (Betadine leaves), traditionally used as antiseptics. Objective: To assess the antibacterial activity of endophytic bacterial isolates from Betadine leaves against Staphylococcus aureus. Methods: A laboratory-based experimental study employing the paper disc diffusion method. Endophytic isolates were cultured in Nutrient Broth, and centrifuged supernatants were tested for inhibition zones compared to positive (chloramphenicol) and negative (Na.CMC) controls. Results: The endophytic isolate produced a 16.11 mm inhibition zone (moderate activity), while chloramphenicol showed 27.63 mm (strong activity). No inhibition was observed in the negative control. Conclusion: Endophytic bacteria from Betadine leaves exhibit potential as natural antibacterial agents, though their efficacy is lower than standard antibiotics. Further development requires active compound characterization and toxicity studies.
Co-Authors Arfiandi, Arfiandi Fadjria, Neri Nofita, Dewi Noviani Nurul Aziza, Nurul