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All Journal Bali Dermatology and Venereology Journal Bali Dermatology Venereology and Aesthetic Journal
Priyadarshini, Ida Ayu Uttari
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Case report: a child with type 1 neurofibromatosis and intellectual disability Wijaya, Elice; Karna, Ni Luh Putu Ratih Vibriyanti; Priyadarshini, Ida Ayu Uttari
Bali Dermatology and Venereology Journal Vol 4, No 2 (2021)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v4i2.55

Abstract

Background: Neurofibromatosis is a genetic disorder which manifests as a tumor that surrounds the nerves and several other pathologic presentations.Case: Female, 11 years old, according to history, physical examination and supporting investigation was consistent with the diagnostic criteria of type 1 neurofibromatosis (NF-1). Patient also has intellectual disability. On the patient, a tumor on the foot region that was functionally disabling was found and a surgical treatment was performed.Discussion: Cognitive disorder is the most common neurological complication in individuals with NF-1 and usually present with low intelligence quotient (IQ). There is no specific treatment to prevent the development of NF-1. However, early treatment can minimize and prevent further complication. Treatment for the patient involve multiple clinical discipline.Conclusion: A neurofibromatosis case can be diagnosed clinically alone, however, since there are many other systemic involvements that require multi-disciplinary approach.
A case report of an elderly with herpes zoster and atrial fibrillation taking warfarin Putra, Gilang; Devina, Wilona; Priyadarshini, Ida Ayu Uttari
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.101

Abstract

Background: Herpes zoster (HZ) presents with unilateral dermatomal pain and rash resulting from the reactivation and proliferation of latent varicella zoster virus (VZV) that dwells in neurons following varicella. It mostly occurs in the elderly and in immunocompromised . Warfarin consumption can lead to dysregulation of cytokines that cause immune dysregulation, which can be a factor in the reactivation of herpes zoster. There is limited research or study exploring the correlation between herpes zoster reactivation and the use of warfarin in patients with atrial fibrillation This case report aim to investigate potential role of anticoagulant therapy, specifically warfarin, in the reactivation of HZ in elderly patients, and to explore the implications of polypharmacy and immune dysregulation in the management and prevention of HZ. Case Description: A 55-year-old male with a history of atrial fibrillation, currently on warfarin, was admitted with complaints of pain blister lession that developed 7 days post-discharge from the Cardiology department. His initial symptoms included pruritus and pain localized to the chest and right thoracic area. Dermatological examination revealed herpetiform vesicles on an erythematous base, accompanied by crusts and scabs, distributed along thoracic dermatomes T6-T8. Conclusion: Elderly patients often experience polypharmacy due to degenerative diseases. Cardiovascular treatment often includes anticoagulants such as warfarin. Following 1 week after the administration of topical antibiotic and steroid ointments, the patient demonstrated a positive clinical outcome with a few complications after HZ infection.    
Co-Authors Devina, Wilona Elice Wijaya Ni Luh Putu Ratih Vibriyanti Karna Putra, Gilang