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All Journal Majalah Kedokteran Bandung Bali Dermatology and Venereology Journal Cermin Dunia Kedokteran
Aviana, Felicia
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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Steroid-induced diabetes mellitus in pemphigus vulgaris patient at Bali Mandara Hospital: a case report Aviana, Felicia; Birawan, I Made
Bali Dermatology and Venereology Journal Vol 4, No 2 (2021)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v4i2.43

Abstract

Background: Pemphigus vulgaris (PV) is a blistering autoimmune disease of the skin and mucous membranes defined histologically by intraepidermal blister due to acantholysis. Systemic corticosteroids and immunosuppressive agents had greatly improved the prognosis of pemphigus. However, steroid use often leads to metabolic complications, such as diabetes mellitus. This case report describes steroid-induced diabetes mellitus in PV, where the side effect of long-term high dosages steroid used and the method to manage it can be used as a study case.Case report: A 31-year-old man complained of new blisters from almost the entire body. He had a history of PV 1 year ago and no history of diabetes mellitus in the patient or family. He had a medication history of methylprednisolone 8 mg every 8 hours. Dermatological status showed erythema macules, extensive erosion almost on the entire body, the Nikolsky sign (+), and the Asboe-Hansen sign (+). Blood laboratory result: random blood glucose 451 mg/dl, HbA1c 12.3%.  Histopathological examination: suprabasal blister, in which the basal cells still attached to the basement membrane show a “tombstone” appearance. The diagnosis was steroid-induced diabetes in pemphigus vulgaris. He was treated with steroids and insulin.Conclusion: Steroid use in PV treatment can lead to metabolic complications, such as diabetes mellitus. Regularly monitoring is needed to prevent complications due to steroid use.
Profil Penderita Morbus Hansen di Poliklinik Kulit dan Kelamin RSUD Bali Mandara Januari 2018-Desember 2020 Aviana, Felicia; Birawan, I Made; Sutrini, Ni Nyoman Ayu
Cermin Dunia Kedokteran Vol 49, No 2 (2022): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (91.316 KB) | DOI: 10.55175/cdk.v49i2.1725

Abstract

Morbus Hansen (MH) merupakan salah satu penyakit terabaikan dan masih sering dijumpai di negara tropis dan subtropis, termasuk di Indonesia yang menduduki peringkat ketiga di dunia. Penelitian deskriptif retrospektif dilakukan untuk mengetahui profil penderita MH di PoliklinikKulit dan Kelamin RSUD Bali Mandara periode Januari 2018-Desember 2020. Didapatkan 55 penderita MH dengan 492 (1,6%) kunjungan dari 30587 total kunjungan; terdiri dari 39 (71%) laki-laki dan 16 (29%) perempuan, terbanyak dari kelompok usia 25-44 tahun (45,5%). Berdasarkan tipe MH, didapatkan tipe multibasiler (MB) sebesar 92,7%. Berdasarkan reaksi MH, didapatkan 14,5% pasien dengan reaksi erythema nodosum leprosum (ENL), tidak didapatkan pasien reaksi reversal. Mayoritas penderita MH di Poliklinik Kulit dan Kelamin RSUD Bali Mandara periode Januari 2018-Desember 2020 adalah laki-laki, kelompok usia 25-44 tahun, tipe multibasiler dengan reaksi erythema nodosum leprosum (ENL).
Efek Samping Steroid Sistemik pada Terapi Pemgus Vulgaris Aviana, Felicia; Birawan, I Made
Cermin Dunia Kedokteran Vol 48, No 9 (2021): Nyeri Neuropatik
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (93.257 KB) | DOI: 10.55175/cdk.v48i9.1488

Abstract

Pemfigus vulgaris (PV) adalah penyakit autoimun vesikobulosa pada kulit dan membran mukosa yang secara histologi ditandai bula intraepidermal yang disebabkan oleh akantolisis. Steroid sistemik merupakan terapi utama PV. Artikel ini membahas efek samping terapi steroid parenteral pada pemfigus vulgaris.Pemphigus Vulgaris (PV) is an autoimmune blistering disease of skin and mucous membranes, histologically defined by intraepidermal blister due to acantholysis. Systemic steroid is the first-line treatment in PV. This article briefly discussedthe adverse effect of parenteral steroid in the treatment of pemphigus vulgaris.
Microbial Diversity and Antimicrobial Susceptibility from Wound Dehiscence Isolates in an Indonesian Tertiary Referral Hospital Aviana, Felicia; Fatmawati, Ni Nengah Dwi
Majalah Kedokteran Bandung Vol 56, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v56.3422

Abstract

Healthcare-associated infections (HAIs) remain a critical issue for public health in Indonesia, with wound dehiscence associated with surgical site infections (SSIs) being one of them. Globally, SSIs are known as the most common postoperative complications with a heightened prevalence, particularly in low to middle-income countries. With its retrospective and descriptive design, this study aimed to illustrate the microbial patterns identified in Prof. Dr. I.G.N.G. Ngoerah General Hospital from 12 January 2020 to 12 December 2022. The study includes all patients who underwent surgery and were subsequently diagnosed with wound dehiscence and SSIs. Specimens were collected from patients and submitted to the Microbiology Laboratory at the hospital above. Bacterial identification and susceptibility testing to antimicrobials were performed using the Vitek 2 Compact System (bioMerieux, Marcy l'Etoile, France). Patient information was sourced from medical records. Out of 172 samples, 151 (87.8%) yielded positive cultures. Among these, 151 (87.8%) were found to be positive. Gram-negative bacteria were found to be most prevalent, with Escherichia coli (20.2%) and Pseudomonas aeruginosa (19.6%) being the most frequently isolated bacteria. The bacteria isolated were mostly susceptible to amikacin (72.1%), followed closely by meropenem (71.4%). This information could contribute to the development of an empirical antibiotic therapy protocol for wound dehiscence or SSI cases in this local context.
Co-Authors Birawan, I Made Ni Nengah Dwi Fatmawati Sutrini, Ni Nyoman Ayu