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Lukito, Johan Indra
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Health Professions Medicine & Pharmacology Public Health

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Tinjauan Antivirus untuk Terapi COVID-19 Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 47, No 7 (2020): Bedah
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (571.901 KB) | DOI: 10.55175/cdk.v47i7.595

Abstract

COVID-19 merupakan penyakit yang disebabkan oleh coronavirus baru yang disebut SARS-CoV-2. Pada 11 Maret 2020, WHO mendeklarasikan COVID-19 sebagai pandemi global. Beberapa jenis antivirus diteliti potensinya sebagai terapi untuk COVID-19, di antaranya yaitu: oseltamivir, favipiravir, remdesivir, lopinavir+ritonavir, atazanavir, nelfinavir, saquinavir, tipranavir, darunavir, umifenovir, dan baloxavir.COVID-19 is a disease caused by a new coronavirus called SARS-CoV-2. On March 11, 2020, WHO declared COVID-19 as a global pandemic. Several types of antivirals have been investigated for their potential as therapies for COVID-19, including: oseltamivir, favipiravir, remdesivir, lopinavir+ritonavir, atazanavir, nelfinavir, saquinavir, tipranavir, darunavir, umifenovir, dan baloxavir.
Antibiotik Profilaksis pada Tindakan Bedah Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 46, No 12 (2019): Kardiovaskular
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (202.259 KB) | DOI: 10.55175/cdk.v46i12.401

Abstract

Antibiotik profilaksis pra-operasi didefinisikan sebagai pemberian antibiotik sebelum operasi untuk mengurangi risiko infeksi pasca operasi. Antibiotik profilaksis optimal untuk pembedahan idealnya sesuai pedoman penggunaan antibiotik profilaksis atau pedoman lokal. Kriteria antibiotik profilaksis dalam pembedahan yang tepat meliputi tepat indikasi, tepat jenis antibiotik, tepat dosis, tepat rute, tepat waktu dan durasi pemberian.Preoperative antibiotic prophylaxis is defined as administration of antibiotics prior to surgical procedure to decrease postoperative infection risk. The optimal antibiotic prophylaxis for surgery is ideally in accordance with the guidelines. The key elements of appropriate surgical antimicrobial prophylaxis prescribing include correct indication, antimicrobial, drug dose, route, timing of administration and duration.
Gunakan Insulin dengan CERMAT Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 47, No 10 (2020): Optalmologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.313 KB) | DOI: 10.55175/cdk.v47i10.1093

Abstract

Insulin digunakan sebagai salah satu terapi diabetes melitus (DM). Penderita DM dan keluarganya perlu mendapat edukasi tentang penggunaan insulin. Penulis menyusun sebuah mnemonik untuk membantu pasien dan keluarganya mengingat hal-hal penting terkait penggunaan insulin. Mnemonik ini berupa slogan “Gunakan Insulin dengan CERMAT”.Insulin is used for diabetes mellitus (DM) therapy. DM sufferers and their families need to be educated on using insulin to control their blood glucose levels. The author suggested a mnemonic to help patients and their families remember essential points related to insulin use. This mnemonic is "Use Insulin with CERMAT". 
Antidiabetik Oral Kombinasi Penghambat DPP-4 dan Penghambat SGLT-2 Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 48, No 12 (2021): General Medicine
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (96.001 KB) | DOI: 10.55175/cdk.v48i12.1572

Abstract

Dalam tatalaksana diabetes melitus tipe 2, terapi kombinasi dua obat antidiabetik disarankan jika dengan monoterapi gagal mencapai target kontrol glikemik. Pemilihan jenis obat antidiabetik tergantung kondisi pasien dan profil obat. Kombinasi obat antidiabetik oral golongan penghambat DPP-4 (dipeptidyl peptidase-4) dan penghambat SGLT-2 (sodium-glucose cotransporter type 2) dapat menjadi salah satu pilihan.Combination of two antidiabetic drugs is recommended in the management of type 2 diabetes mellitus if monotherapy fails to achieve glycemic control targets. Choice of antidiabetic drugs depends on the patient's condition and drugs’ profile. Combination of oral antidiabetic drugs DPP-4 (dipeptidyl peptidase-4) class and SGLT-2 (sodium-glucose cotransporter type 2) inhibitors can be an option.
Tatalaksana Monkeypox Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 46, No 8 (2019): Kesehatan Anak
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (293.515 KB) | DOI: 10.55175/cdk.v46i8.447

Abstract

Monkeypox merupakan penyakit zoonosis akibat virus yang terjadi terutama di daerah hutan hujan tropis Afrika tengah dan barat. Virus monkeypox mirip cacar. Meskipun monkeypox jauh lebih ringan daripada cacar, namun dapat fatal. Virus monkeypox sebagian besar ditularkan ke manusia dari berbagai binatang liar seperti tikus dan primata, juga dapat ditularkan dari manusia ke manusia. Tingkat kematian saat wabah monkeypox antara 1% - 10%, sebagian besar pada kelompok usia lebih muda. Tidak ada pengobatan atau vaksin khusus namun vaksinasi cacar sangat efektif mencegah monkeypox.Monkeypox is a viral zoonotic disease that occurs primarily in remote tropical rainforests of central and west Africa. The monkeypox virus is similar to human smallpox virus. Although monkeypox is much milder than smallpox, it can also be fatal. Monkeypox virus is mostly transmitted to people from various wild animals such as rodents and primates, it can also spread through human-to-human transmission. Case fatality in monkeypox outbreaks is between 1% - 10%, most deaths occurred in younger age groups. No specific treatment or vaccine available, although smallpox vaccination was also highly effective in preventing monkeypox.
Pengembangan Aplikasi Seluler Kesehatan terkait Diabetes Melitus Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 48, No 10 (2021): CME - Continuing Medical Education
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.752 KB) | DOI: 10.55175/cdk.v48i10.1516

Abstract

Peningkatan kualitas hidup pasien diabetes melitus (DM) membutuhkan pengelolaan komprehensif. Beberapa tantangan dihadapi baik oleh pasien maupun profesional kesehatan dalam tatalaksana DM. Penggunaan dan pengembangan aplikasi seluler kesehatan berbasis telemedicine dan teknologi informasi kesehatan diharapkan dapat membantu mengatasi tantangan ini.Improving the quality of life of patients with diabetes mellitus (DM) requires comprehensive management. Several challenges are faced by both patients and health professionals in the management of DM. It is hoped that the use and development of mobile health applications based on telemedicine and health information technology can help overcome this challenge.
Tinjauan atas Terapi Insulin Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 47, No 9 (2020): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (482.438 KB) | DOI: 10.55175/cdk.v47i9.917

Abstract

Tujuan terapi insulin adalah meniru pola sekresi insulin endogen individu normal. Berbagai jenis insulin dapat dibagi menjadi 3 kelompok utama : insulin kerja cepat/pendek, insulin kerja menengah dan insulin kerja panjang. Pemilihan regimen insulin disesuaikan dengan berbagai kondisi dan kebutuhan.The goal of insulin therapy is to mimic the pattern of normal endogenous insulin secretion. Various types of insulin can be divided into 3 main groups: fast/short-acting insulin, intermediate-acting insulin, and long-acting insulin. The choice of insulin regimen is adapted to various conditions and needs.
Diagnosis dan Farmakoterapi Penyakit Paru Obstruktif Kronis: Tinjauan Pustaka Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 52 No 10 (2025): Kedokteran Umum
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i10.1682

Abstract

Chronic obstructive pulmonary disease (COPD) is a lung disease with chronic respiratory symptoms and exacerbations that can be prevented and treated. COPD is characterized by airfow obstruction that is not fully reversible, generally due to long-term exposure to cigarette smoke, pollution, or other environmental risk factors. Multiaspect COPD assessment after confrmation of COPD diagnosis is needed to guide treatment. The diagnosis is established by spirometry and clinical evaluation, including assessment of symptoms, history of exacerbations, blood eosinophil levels, and the presence of comorbidities. COPD pharmacotherapy aims to reduce symptoms, reduce the risk of exacerbations, and improve the patient’s quality of life. Pharmacotherapy is administered during stable conditions or during exacerbations using bronchodilators alone or in combination, corticosteroids, and other supportive medications according to the patient’s needs, abilities, and condition. Personalized therapy based on symptom severity, history of exacerbations, and patient response. Regular monitoring, proper inhaler technique, and treatment adherence are essential for achieving optimal clinical outcomes.
Tren Penggunaan Antibiotik Lukito, Johan Indra
Cermin Dunia Kedokteran Vol 50 No 12 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i12.1049

Abstract

Resistensi antibiotik mengancam pencegahan dan pengobatan efektif berbagai infeksi bakteri yang kejadiannya terus meningkat. Berbagai langkah untuk mencegah dan mengendalikan resistensi antibiotik, di antaranya dengan mengoptimalkan penggunaan antibiotik yang sudah ada, serta melakukan penelitian dan pengembangan antibiotik baru.
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