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All Journal Cermin Dunia Kedokteran Magna Neurologica

Mahendrakrisna, Daniel

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Author-ID : 2225273

Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Articles

Keracunan Tanaman Kecubung Mahendrakrisna, Daniel; Al Firdausi, Khadijah Nur
Cermin Dunia Kedokteran Vol 47, No 11 (2020): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Keracunan tanaman Datura stramonium atau yang dikenal sebagai tanaman kecubung perlu mendapatkan perhatian. Tanaman ini mudah ditemukan; dapat disalahgunakan sebagai zat psikotropika. Gejala klinis kasus ini adalah gejala peningkatan saraf parasimpatis berupa midriasis, kulit kering, takikardia. Tatalaksana keracunan tanaman Kecubung suportif, umumnya akan membaik sendiri; jika berat dapat diberi reversible cholinesterase inhibitor seperti physostigmine.Datura stramonium, known as Kecubung flower in Indonesia, is a plant often used as a medicine; this plant is also often abused as psychotropics. The clinical symptoms in this case are increased parasympathetic activities such as mydriasis, dry skin, and tachycardia. Datura intoxication treatment is supportive. In severe cases, reversible cholinesterase inhibitor such as physostigmine should be used.

Tatalaksana Epilepsi Refrakter Mahendrakrisna, Daniel; Taslim Pinzon, Rizaldy
Cermin Dunia Kedokteran Vol 47, No 9 (2020): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Epilepsi refrakter atau resisten obat didefinisikan sebagai kegagalan respon terhadap dua obat anti epilepsi sesuai jadual, dosis, dan rute pemberian, baik monoterapi maupun kombinasi, untuk tercapainya bebas serangan. Serangan epilepsi yang tidak terkontrol atau resisten obat umumnya berkaitan dengan prognosis buruk, dan mengganggu kualitas hidup. Beberapa pilihan terapi kasus epilepsi refrakter yaitu Diet Ketogenik, Deep Brain Stimulator (DBS), Vagal Nerve Stimulator (VNS), Transcranial Magnetic Stimulation (TMS), Responsive Cortical Neuro-Stimulator (RNS), dan Pembedahan. Terapi lini pertama adalah pembedahan reseksi,Refractory epilepsy is defined as an epilepsy unresponsive to two or more anti epileptic drugs with proper schedule and doses, on monotherapy and combined therapy, to achieve seizures freedom. Refractory epilepsy was associated with poor prognostic and decreased quality of life. Several alternatives for refractory epilepsy are ketogenic diet, Deep Brain Stimulator (DBS), Vagal Nerve Stimulator (VNS), Transcranial Magnetic Stimulation (TMS), Responsive Cortical Neuro-Stimulator (RNS), and surgery. The first line therapy for refractory epilepsy is resection surgery.

Karakteristik Pasien Stroke Usia Muda di RSUD Kota Surakarta Mahendrakrisna, Daniel; Windriya, Drestha Pratita; Chandra GTS, Aria
Cermin Dunia Kedokteran Vol 46, No 3 (2019): Nutrisi
Publisher : PT. Kalbe Farma Tbk.

Latar Belakang. Kejadian stroke pada usia muda kurang dari 5% dari seluruh kejadian stroke. Beberapa penelitian melaporkan peningkatan angka kejadian stroke pada usia kurang dari 45 tahun. Penelitian ini untuk mengetahui angka kejadian dan karakteristik pasien stroke usia muda di RSUD Kota Surakarta. Metode. Penelitian deskriptif observatif pada populasi semua penderita stroke usia muda (18-45 tahun) di RSUD Kota Surakarta dari bulan Januari 2017 hingga Juni 2018. Data diambil dari rekam medis berupa usia, jenis kelamin, jenis stroke, hasil CT scan, serta faktor risiko. Hasil. Dari 420 pasien stroke pada rentang waktu Januari 2017-Juni 2018, didapatkan 28 penderita stroke usia muda, rerata usia 39.6 tahun dengan rentang usia 29 sampai 45 tahun, 53.6 % laki-laki, 78.6% menderita stroke non hemoragik, 39.3% menderita kelemahan sisi kanan. Didapatkan riwayat hipertensi pada 85.7%, diabetes mellitus pada 14.3%, hiperkolesterolemia 17.9%, hiperurisemia 21.4%, gagal jantung 7.1%, epilepsi 7.1%, dan riwayat stroke 3.6%. Tidak ada yang mempunyai riwayat penyakit jantung koroner dan aritmia jantung. Simpulan. Stroke usia muda jarang, sebagian besar non hemoragik. Hipertensi dan dislipidemia juga merupakan faktor risiko utama stroke di usia muda.Introduction. Stroke in young adults is less than 5% of all incidence of stroke; but it is increasing among less than 45 years old. The purpose of this study was to determine the incidence and characteristics of young stroke patients in RSUD Kota Surakarta. Method. A descriptive analytic study on all stroke patients aged between 18-45 years in RSUD Kota Surakarta during January 2017 to June 2018. Data was collected from medical record consist of age, gender, type of stroke, CT scan data and risk factors. Result. From 420 stroke patients in the period of January 2017-June 2018, there were 28 young stroke patients in the range of 29 to 45 years old, the average was 39.6 years old; 53.6% were male and 78.6% suffered a non-hemorrhagic stroke, 39.3% had right hemiparesis. Hypertension was found in 85.7%, diabetes mellitus in 14.3%, dyslipidemia in 17.9%, high uric acid in 21.4%, heart failure in 7.1%, epilepsy in 7.1%, and previous stroke history in 3.6% patients. No patients has a history of coronary heart disease and cardiac arrhythmias. Conclusion.The young adults stroke incidence is low. Ischemic stroke is the most common type. Hypertension and dyslipidemia are the most common found stroke risk factors.

Diagnosis Sindrom Piriformis Mahendrakrisna, Daniel
Cermin Dunia Kedokteran Vol 46, No 7 (2019): CME - Continuing Medical Education
Publisher : PT. Kalbe Farma Tbk.

Sindrom piriformis adalah neuropati perifer kompresi muskulus piriformis pada nervus iskiadikus. Kelainan ini banyak ditemukan pada wanita dan cenderung luput dari diagnosis karena banyaknya penyakit dengan gejala sama. Aktivitas berlebihan dan duduk lama merupakan pencetus. Gejala dan pemeriksaan fisik sederhana seperti Pace sign, Freiberg sign, pyriformis sign, dan Beatty sign dapat membantu diagnosis. Tatalaksana mencakup farmakologi obat anti inflamasi non steroid, fisioterapi, psikoterapi, serta pembedahan.Piriformis syndrome (PS) is a neuropathy due to compression to sciatic nerve lying on piriformis muscle. PS are more commonly found in women. Excessive activities and sitting could be precipitating factors. PS is often misdiagnosed because of many diseases with similar symptoms. Physical signs, such as Pace sign, Freiberg sign, piriformis sign, and Beatty sign, could aid to diagnosis. Non-steroidal anti inflammatory agent, physioterapy, psychotherapy, and surgery could reduce the symptoms.Â

Gambaran Kasus Leptospirosis di RSUD Kota Surakarta, 2015-2018 Suprapto, Ivan Aristo; Mahendrakrisna, Daniel; Indianto, Wahyu; Hudiyanti, Vivin
Cermin Dunia Kedokteran Vol 47, No 2 (2020): Penyakit Infeksi
Publisher : PT. Kalbe Farma Tbk.

Latar Belakang. Indonesia memiliki angka kejadian leptospirosis masih cukup tinggi, terutama di beberapa kota besar di Indonesia. Metode. Penelitian deskriptif analitik di Rumah Sakit Umum Daerah Kota Surakarta. Populasi penelitian ini adalah penderita leptospirosis di RSUD Kota Surakarta pada periode Januari 2015 hingga April 2018. Data demografik merupakan data sekunder dari rekam medis berupa usia, jenis kelamin, alamat, daerah tinggal, riwayat paparan atau pekerjaan, bulan dan tahun rawat, kondisi saat pulang, diagnosis, gejala klinis pendukung kasus suspek dan kasus probable, dan hasil serokonversi. Analisis uji univariat dengan data nominal dipresentasikan menggunakan frekuensi dan persentase. Hasil. Total ada 100 penderita pada penelitian ini terutama pada usia produktif yaitu kelompok usia 46-60 tahun (42.6%) dan laki-laki (81%). Rerata usia 49.98 tahun. Kota Solo merupakan daerah asal pasien terbanyak sebesar 51%, dan 39% bertempat tinggal di kecamatan Banjarsari di kota Solo. Kasus leptospirosis lebih sering pada musim penghujan puncaknya bulan Maret (24%). Insidensi leptospirosis terbanyak di tahun 2017 yaitu 39 kasus (39%). Simpulan. Insiden leptospirosis di kota Surakarta dan sekitarnya masih tergolong tinggi.Background. Indonesia has a high reported leptospirosis incidence, especially in several major cities in Indonesia. Method. This study is a descriptive analytic study conducted at the Surakarta City General Hospital. The population was leptospirosis patients in Surakarta City Hospital in the period January 2015 to April 2018. Secondary demographic data was taken from medical records; consist of age, sex, address, area of residence, exposure history or occupation, month and year of admission, clinical symptoms, diagnosis, conditions at discharge, and seroconversion results. Statistical univariate analysis with nominal data presented using frequency and percentage. Results. From 100 leptospirosis patients in this study, the average age of subjects was 49.98 years; mostly male (81%) in productive age group 46-60 years (42.6%). Most patients came from the city of Solo (51%), and 39% live in the sub-district Banjarsari. Leptospirosis cases are more common in the peak rainy season in March (24%). The highest incidence with 39 cases (39%) was in 2017. Conclusion. The incidence of leptospirosis in Surakarta and surrounding cities is still relatively high.

A Rare Case of Anomic Aphasia and Gerstmann Syndrome Induced by Hemorrhagic Stroke Mahendrakrisna, Daniel; Bagus Ngurah Mahasena Putera Awatara; Gede Suputra; Ni Wayan Nurlina Ekasari; Dian Kusumastuti Anggraeni Putri; Anak Agung Ayu Putri Laksmidewi
Magna Neurologica Vol. 3 No. 2 (2025): July
Publisher : Department of Neurology Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/magnaneurologica.v3i2.2262

Background: Aphasia is a language disorder caused by brain damage, such as a stroke. Anomic aphasia, a rare subtype, impairs the ability to name objects or people while preserving fluency and comprehension. It is often associated with Gerstmann syndrome, which is characterized by acalculia, finger agnosia, left-right disorientation, and semantic aphasia. This report presents a case of a 61-year-old male with anomic aphasia and Gerstmann syndrome following a hemorrhagic stroke. Case: A 61-year-old male patient presented with sudden difficulty recalling the names of family members and objects. Imaging revealed an intracerebral hemorrhage in the left parietotemporooccipital lobe. The patient also exhibited left-right disorientation and finger agnosia, indicative of Gerstmann syndrome. The Aphasia Test for Rehabilitation Information Diagnosis (TADIR) confirmed the diagnosis of anomic aphasia. Although conservative treatment led to partial improvement, naming difficulties and associated deficits persisted. Discussion: Anomic aphasia primarily involves difficulties with naming, typically resulting from lesions in the dominant hemisphere, particularly the temporal and parietal lobes. Its coexistence with Gerstmann syndrome underscores the complexity of overlapping neurological deficits. The TADIR test was crucial in diagnosing and managing the patient's condition. Conclusion: This case highlights the importance of a thorough evaluation in aphasia cases, especially when rare syndromes like Gerstmann syndrome are involved. Early and accurate diagnosis enables targeted interventions that can improve patient outcomes.

Co-Authors Al Firdausi, Khadijah Nur Anak Agung Ayu Putri Laksmidewi Bagus Ngurah Mahasena Putera Awatara Chandra GTS, Aria Dian Kusumastuti Anggraeni Putri Gede Suputra Ni Wayan Nurlina Ekasari Suprapto, Ivan Aristo Taslim Pinzon, Rizaldy Vivin Hudiyanti Wahyu Indianto, Wahyu Windriya, Drestha Pratita

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