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All Journal e-CliniC Cermin Dunia Kedokteran Ophthalmologica Indonesiana
Rusli, Richardo
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Health Professions Medicine & Pharmacology Public Health

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Retinitis Pigmentosa Rusli, Richardo
Cermin Dunia Kedokteran Vol 47, No 7 (2020): Bedah
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (555.23 KB) | DOI: 10.55175/cdk.v47i7.597

Abstract

Retinitis pigmentosa merupakan sekelompok penyakit degenerasi retina herediter yang ditandai oleh disfungsi progresif fotoreseptor disertai hilangnya sel secara progresif dan akhirnya menyebabkan atrofi beberapa lapisan retina. Beberapa kasus retinitis pigmentosa merupakan penyakit genetik yang diturunkan secara Mendel. Pada funduskopi, dapat ditemukan perubahan pigmen retina seperti bone spicules. ERG menunjukkan dominasi penurunan amplitudo gelombang-b dalam kondisi skotopik. Farmakoterapi vitamin A, Docosahexaenoic acid (DHA), lutein/zeaxanthin bertujuan untuk mengurangi morbiditas dan mencegah komplikasi.Retinitis pigmentosa is a group of hereditary retinal degeneration characterized by progressive photoreceptor dysfunction and is accompanied by progressive cell loss and eventually causes atrophy in several layers of the retina. Almost all types of retinitis pigmentosa are inherited, caused by errors in genetic information. In funduscopy, changes in retinal pigment can be found in the form of bone spicules. ERG shows a decrease in the b-wave amplitude that dominates in scotopic conditions. Pharmacotherapy such as vitamin A, docosahexaenoic acid (DHA), lutein / zeaxanthin aims to reduce morbidity and prevent complications.
Long-Term Outcomes of Cataract Surgery: Analysis of Visual Acuity and Intraocular Pressure in a Tertiary Care Center Nursalim, Ade J.; Sumual, Vera; Chietra, Andrew; Emily, Ardelia; Rusli, Richardo
e-CliniC Vol. 12 No. 3 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i3.58044

Abstract

Abstract: Posterior capsule opacity (PCO) is a common complication following cataract surgery, caused by the proliferation of residual lens epithelial cells. This study aimed to evaluate the long-term effects of Nd:YAG laser capsulotomy on intraocular pressure (IOP) and visual acuity in PCO patients. This was a retrospective descriptive study. Samples were 24 patients diagnosed with PCO who underwent Nd:YAG laser capsulotomy at Prof. Dr. R. D. Kandou Hospital, Manado, from January 1, 2022, to January 1, 2024. The study recorded pre- and post-procedure IOP and best-corrected visual acuity (BCVA) data. Descriptive analysis, including paired t-tests, was used to assess changes in IOP and BCVA over an average follow-up period of 19.2 months. The results showed a statistically significant improvement in BCVA (p=0.000), with mean values improving from 0.72 to 0.27 LogMAR. A significant reduction in IOP was also observed (p=0.015), with long-term IOP remaining stable. A weak correlation was found between follow-up duration and IOP variation (p=0.02). In conclusion, Nd:YAG laser capsulotomy significantly improves visual acuity and stabilizes intraocular pressure in the long term for PCO patients, suggesting its effectiveness in managing post-cataract surgery complications. Keywords: posterior capsule opacity; Nd:YAG laser capsulotomy; intraocular pressure; visual acuity; cataract surgery    
The Effects of Bevacizumab in Augmenting Trabeculectomy for Glaucoma : Systematic Review and Meta-Analysis: Poster Presentation - Observational Study - Resident Rusli, Richardo; Kasih, Franky Richard
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/byaet056

Abstract

Introduction & Objectives : Anti-vascular endothelial growth factor (VEGF) agents have been used to slow the healing response and postoperative scar tissue formation. To determine the effectiveness of adding Anti VEGF bevacizumab to the results of trabeculectomy in glaucoma. Methods : Searches were conducted in a structured way using keywords across several data sources, including Pubmed, Proquest and Cochrane library. The keywords used for searching were “Bevacizumab”, “Trabeculectomy” and “Glaucoma”. The reviewed articles are Randomized Control Trial in english, conducted on humans in the last 15 years. The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Results : From a total of 353 articles, there were 6 studies with 362 eyes of 352 patients been evaluated for the effectiveness of bevacizumab addition to trabeculectomy. The primary outcome of all articles was the assessment of Intra Ocular Pressure (IOP). No significant difference in IOP was found between the subconjunctival bevacizumab + Mytomycin-c group and mytomycin-c alone group (MD 0.11 ; 95% CI -0.10 to 0.33), as well as subconjunctival comparison with mytomycin-c (MD 0.11 ; 95% CI -0.29 to 0.50). Similar results were also found in the intracameral and placebo groups (MD 0.08 ; -0.22 to 0.38). However, 3 articles reported significant differences in peripheral vascularity of the bleb both by the Moorfields Bleb Grading System and by the Indiana Bleb Appearance System. Conclusion : The addition of bevacizumab to trabeculectomy did not show any benefit in reducing IOP when compared with MMC. But it gives better peripheral vascularity of the bleb.
Challanges Prepupillary Iris Claw Implantation In Irregular-Shaped Pupil: Poster Presentation - Case Report - Resident Rusli, Richardo; Umboh, Roy
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/96cm5173

Abstract

Introduction : For decades secondary implants carry a greater risk of high complications. The iris claw technique is popular because of the safe and fast IOL implantation. But, in this case there is a difficulty where the pupil shape is irregular so that it is a challenge for enclavation the haptic on the prepupillary iris. Case Illustration : A man, 39 YO, came with complaints of blurred right eye after surgery on the right eye 6 months ago. Vision 1/60 with pinhole reaching 20/70, , deep anterior chamber with VH 4, positive iris tremulans, with irregular shape in temporal regio where is the main port where the first operation was performed, not centrally located pupil. There was no intraocular lens found in the lens. The patient was planned for the installation of a Secondary IOL in the right eye with a prepupillary iris claw and endodiathermal pupilloplasty to returns the pupil to the central position. One day after surgery, visual acuity was 1/300, IOP was 30 mmHg and the descment fold. The anterior chamber is difficult to evaluate. 4 weeks after surgery, Vision was 20/70, cornea was clear and IOP was 17mmHg without the need for return surgery. Discussion : Until now, there is still no consensus regarding the best management options to correct aphakia without adequate lens capsule support. Endothermal diathermy pupilloplasty itself aims to create and maintain an appropriate pupil size. Conclusion : Even though there are complications, the installation of the iris claw on the prepupillary is still a safe technique for aphakic correction.
Co-Authors Chietra, Andrew Emily, Ardelia Kasih, Franky Richard Nursalim, Ade J. Umboh, Roy Vera Sumual