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Anensefali Diduga Akibat Defisiensi Asam Folat Erdiana, Grace
Cermin Dunia Kedokteran Vol 48, No 7 (2021): Infeksi - [Covid - 19]
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (112.248 KB) | DOI: 10.55175/cdk.v48i7.1455

Abstract

Anensefali merupakan bagian dari Neural Tube Defect (NTD) yang disebabkan kegagalan penutupan tabung saraf. Salah satu faktor yang paling berpengaruh terhadap anensefali adalah kurangnya asam folat saat masa prekonsepsi dan awal kehamilan. Dilaporkan seorang wanita G3P1A1 umur 25 tahun dengan usia kehamilan 40 minggu, cukup bulan dan janin anensefali. Riwayat persalinan sebelumnya tidak pernah mengalami hal serupa. Selama hamil pasien tidak pernah mengonsumsi asam folat. Pasien melahirkan pervaginam, bayi anensefali meninggal 4 jam setelah dilahirkan. Kondisi pasien stabil dan diperbolehkan pulang.Anencephaly is part of Neural Tube Deffect (NTD) caused by failure of neural tube closure. One of the most influential factor is folic acid deficiency during preconception and early pregnancy. Case : G3P1A1 woman aged 25 years with 40 weeks of gestation, presented in emergency unit with aterm pregnancy with anencephaly. Previous childbirth history is negative. During pregnancy, patient never consumes folic acid. The baby was vaginally delivered, died 4 hours after birth. Patient was discharged with stable condition.
Resistensi Antibiotik pada Infeksi Saluran Kemih Anak: Tinjauan Pustaka Erdiana, Grace; Teng, Hendratno Halim
Cermin Dunia Kedokteran Vol 52 No 9 (2025): Pediatri
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i9.1608

Abstract

Urinary tract infection (UTI) is one of the most common infections in children. This infection occurs when bacteria from the urethra ascend into the urinary tract, causing an infection that extends from the urethra to the renal parenchyma. The etiology could be bacteria, virus, or fungi, mostly caused by Escherichia coli (E. coli). Urine culture is the gold standard for UTI diagnosis and to determine appropriate therapy, especially antibiotics. Antibiotic resistance is a global issue, as 80% of healthcare facilities prescribe antibiotics for treatment. The incidence of resistance is higher in developed countries than in non-developed countries, with the highest incidence occurring in children aged 0-5 years. Antibiotic resistance increases mortality and morbidity and is also associated with higher costs. In the case of ISK, E. coli is also the pathogen with the highest incidence of antibiotic resistance, which may be associated with inappropriate use of antibiotics. The ease of obtaining antibiotics without a doctor’s prescription and a history of previous antibiotic use are factors that contribute to antibiotic resistance.
Hubungan Tekanan Darah dan Indeks Massa Tubuh terhadap Kapasitas Vital Paru pada Remaja Sekolah Menengah Atas Adjie, Eko Kristanto Kunta; Ernawati, Ernawati; Erdiana, Grace; Firmansyah, Yohanes; Santoso, Alexander Halim; Nathaniel, Fernandho; Wijaya, Dean Ascha
MAHESA : Malahayati Health Student Journal Vol 4, No 1 (2024): Volume 4 Nomor 1 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i1.11997

Abstract

ABSTRACT Respiratory health can be determined based on the quality of lung function. Decreased lung capacity can affect lung function. The mechanism of this reduction depends on the underlying cause. This study aims to see the effect of body mass index (BMI) and blood pressure on lung vital capacity in adolescents. This research is a cross-sectional study conducted at the Kalam Kudus High School in June 2023, and involved teenage students in grades 10 and 11 aged 15-17 years. Analytical analysis uses the Linear Regression method, with the enter method, which aims to identify the factors that most influence the dependent variable. The results of the regression test stated that only BMI had a statistically significant effect on lung vital capacity (p-value: <0.001). From the analysis results, it was found that BMI significantly affects lung vital capacity. Further research is needed to assess other factors that affect lung vital capacity. Keywords: Lung Vital Capacity, Blood Pressure, BMI  ABSTRAK Kesehatan saluran pernafasan dapat ditentukan berdasarkan kualitas fungsi paru-paru. Penurunan kapasitas paru dapat memengaruhi fungsi paru-paru. Mekanisme dari penurunan tersebut bergantung pada penyebab yang mendasari. Penlitian ini bertujuan untuk melihat pengaruh dari indeks masa tubuh (IMT) dan tekanan darah terhadap kapasitas vital paru pada remaja. Penelitian ini merupakan penelitian potong lintang yang dilakukan di Sekolah Menengah Atas (SMA) Kalam Kudus pada bulan Juni 2023, dan melibatkan siswa-siswi remaja yang berada di kelas X dan XI berusia 15-17 tahun. Analisis deskriptif berupa data untuk variabel kuantitatif dan proporsi (%) untuk variabel kualitatif. Analisis analitik menggunakan metode Regresi Linear, dengan enter method, yang bertujuan untuk mengidentifikasi faktor-faktor yang paling berpengaruh terhadap variabel tergantung. Hasil uji regresi menyatakan bahwa hanya IMT yang berpengaruh signifikan secara statistik dengan kapasitas vital paru (p-value: < 0,001). Dari hasil analisis didapatkan IMT memengaruhi kapasitas vital paru secara signifikan. Penelitian lebih lanjut diperlukan untuk menilai faktor lain yang memengaruhi kapasitas vital paru. Kata Kunci: Kapasitas Vital Paru, Tekanan Darah, IMT