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Octoviani Kristianto, Michelle
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Health Professions Medicine & Pharmacology Public Health

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Diagnosis dan Tatalaksana Non Cirrhotic Portal Hypertension Daniella, Dian; Octoviani Kristianto, Michelle
Cermin Dunia Kedokteran Vol 45, No 12 (2018): Farmakologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (105.884 KB) | DOI: 10.55175/cdk.v45i12.548

Abstract

Non-cirrhotic portal hypertension (NCPH) merupakan hipertensi portal tanpa sirosis, terjadi pada 10% pasien hipertensi portal. Komplikasi paling sering NCPH adalah varises esofagus yang jug amerupakan penyebab kematian erbanyak.Penyakit ini sulit didiagnosis karena prevalensi rendah dan manifestasi klinis beragam, umumnya varises esofagus, splenomegali dan anemia. Pemerikaan ultrasonografi dan biopsi hepar hasilnya normal. Terapi NCPH adalah beta-blocker untuk mengurangi tekanan portal, terapi endoskopik untuk mengatasi varises esophagus dan operasi.Non-cirrhotic portal hypertension (NCPH) is a portal hypertension that occurs in the absence of cirrhosis, which occurs only in 10% portal hypertensive patients. The most frequent complication of NCPH is esophageal varices that is also the leading cause of death. Diagnosis is difficult because of low prevalence and multiple clinical manifestations, usually as esophageal varices, splenomegaly and anemia, while ultrasonographic and liver biopsy are normal. Treatment is beta-blockers to reduce portal pressure, endoscopic therapy to overcome esophageal varices and surgery.
Co-Authors Daniella, Dian